Abstract: A method for treatment of a brain and/or spinal cord includes inserting a flexible catheter into a cerebrospinal fluid space, the flexible catheter including two lumens adapted to allow a fluid to circulate therein in a closed loop within the flexible catheter and the flexible catheter being adapted to be connected to a device for cooling and circulating the fluid. The cerebrospinal fluid in the cerebrospinal fluid space is cooled with the flexible catheter to enable selective central nervous system cooling. The functional status of the brain and/or spinal cord is monitored, and the treatment of the brain and/or spinal cord is modified to adjust for any change in the functional status of the brain and/or spinal cord.

Abstract: An apparatus and method use a catheter for specific and discriminate treatment of central nervous system disease. With the catheter, selective hypothermia to the brain and/or the spinal cord for injury protection can be achieved without the need for systemic cooling. The catheter is also capable of draining excess cerebrospinal fluid.

Abstract: A fixation device includes a first anchor portion configured to join to a first bone portion, a second anchor portion configured to join to a second bone portion, and an intermediate component that extends between the first anchor portion and the second anchor portion. The intermediate component is configured to expand, contract, and angulate enabling constrained movement of the second bone portion with respect to the first bone portion. The second anchor portion has a larger configuration relative to the first anchor portion, thereby preventing the second bone portion from depressing below the first bone portion.

Abstract: A central nervous system drain drains the subdural space intracranially or the postoperative epidural space in the spine. The drain includes one or more lumens that communicate with the outside environment through openings in the distal portion of the drain. The drain also includes a flat bottom wall without any openings which is placed on the brain surface in the subdural space intracranially or the epidural surface in the spinal canal after a laminectomy. The openings in the top wall and/or side surface walls allow for drainage of fluid and/or blood in the subdural space or postoperative wound in the spine.

Abstract: A method for treatment of a brain and/or spinal cord includes inserting a flexible catheter into a cerebrospinal fluid space, the flexible catheter including two lumens adapted to allow a fluid to circulate therein in a closed loop within the flexible catheter and the flexible catheter being adapted to be connected to a device for cooling and circulating the fluid. The cerebrospinal fluid in the cerebrospinal fluid space is cooled with the flexible catheter to enable selective central nervous system cooling. The functional status of the brain and/or spinal cord is monitored, and the treatment of the brain and/or spinal cord is modified to adjust for any change in the functional status of the brain and/or spinal cord.

Abstract: A method for treatment of a brain and/or spinal cord includes inserting a flexible catheter into a cerebrospinal fluid space, the flexible catheter including two lumens adapted to allow a fluid to circulate therein in a closed loop within the flexible catheter and the flexible catheter being adapted to be connected to a device for cooling and circulating the fluid. The cerebrospinal fluid in the cerebrospinal fluid space is cooled with the flexible catheter to enable selective central nervous system cooling. The functional status of the brain and/or spinal cord is monitored, and the treatment of the brain and/or spinal cord is modified to adjust for any change in the functional status of the brain and/or spinal cord.

Abstract: The invention relates to a method of central nervous system pathology treatment through selective hypothermia. Brain and spinal cord cooling is achieved through a closed loop catheter system inserted directly into the cerebrospinal fluid space. The catheter comprises of a portion that dilates in a pulsatile or peristaltic fashion and facilitates circulation of the cooled cerebrospinal fluid.

Abstract: A fixation device includes a first anchor portion configured to join to a first bone portion, a second anchor portion configured to join to a second bone portion, and an intermediate component that extends between the first anchor portion and the second anchor portion. The intermediate component is configured to expand, contract, and angulate enabling constrained movement of the second bone portion with respect to the first bone portion. The second anchor portion has a larger configuration relative to the first anchor portion, thereby preventing the second bone portion from depressing below the first bone portion.

Abstract: The invention relates to a method of central nervous system pathology treatment through selective hypothermia. Brain and spinal cord cooling is achieved through a closed loop catheter system inserted directly into the cerebrospinal fluid space. The catheter comprises of a portion that dilates in a pulsatile or peristaltic fashion and facilitates circulation of the cooled cerebrospinal fluid.

Abstract: An apparatus and method use a catheter for specific and discriminate treatment of central nervous system disease. With the catheter, selective hypothermia to the brain and/or the spinal cord for injury protection can be achieved without the need for systemic cooling. The catheter is also capable of draining excess cerebrospinal fluid.

Abstract: A method for treatment of a brain and/or spinal cord includes inserting a flexible catheter into a cerebrospinal fluid space, the flexible catheter including two lumens adapted to allow a fluid to circulate therein in a closed loop within the flexible catheter and the flexible catheter being adapted to be connected to a device for cooling and circulating the fluid. The cerebrospinal fluid in the cerebrospinal fluid space is cooled with the flexible catheter to enable selective central nervous system cooling. The functional status of the brain and/or spinal cord is monitored, and the treatment of the brain and/or spinal cord is modified to adjust for any change in the functional status of the brain and/or spinal cord.

Abstract: A fixation device comprises a first anchor portion being configured to join to a first bone portion. A second anchor portion is configured to join to a second bone portion. An intermediate component extends between the first anchor portion and the second anchor portion. The intermediate component is configured to expand and contract enabling constrained movement of the second bone portion.

Abstract: Fixation devices and methods for stabilization of the lamina after laminoplasty are described. The device comprises of a plate with several holes that receive bone fasteners. The plate is curved at the ends to contour to the vertebral structure and has appendages to engage the displaced lamina in a fixed position. Alternatively, the plate has a bone fusion spacer in the middle to engage and fuse the lamina in the displaced position. Several methods of dynamically stabilizing the lamina after either the open door, double door or expansive laminoplasty technique are provided.

Abstract: The invention relates to a method of central nervous system pathology treatment through selective hypothermia. Brain and spinal cord cooling is achieved through a closed loop catheter system inserted directly into the cerebrospinal fluid space. The catheter comprises of a portion that dilates in a pulsatile or peristaltic fashion and facilitates circulation of the cooled cerebrospinal fluid.

Abstract: The present invention relates to a craniotomy fixation device and method for fixing a bone flap to the skull following craniotomy. The device may comprise two portions, one portion may be associated with the skull and the other portion may be associated with the bone flap. The two portions are connected in a way to accommodate changes in intracranial pressure.

Abstract: The invention provides a method and apparatus for cranial fixation following a craniotomy and treatment for increased intracranial pressure. The cranial fixation device comprises of plates attached to the skull with a telescopic screw. The telescopic screw provides constrained movement of the bone flap relative to the skull to accommodate an increase in the intracranial pressure.

Abstract: The present invention relates various embodiments of a laminoplasty implant comprising a telescopic spacer configured to attach to the vertebra and adjust the space between two cut portions of a vertebra.

Abstract: Certain embodiments of the present invention include a cranial fixation device for fixing a bone flap to the skull following a craniotomy. The device may accommodate variations in intracranial pressure without allowing the bone flap to move inward beyond the skull surface. Other embodiments include a method for cranial fixation. The method may include joining the bone flap to one portion of the fixation device and joining the skull to another portion of the fixation device. The method may also include responding to changes in intracranial pressure. The method may also include upward and downward movement of the fixation device and constraining the movement of the bone flap.

Abstract: Fixation devices and methods for stabilization of the lamina after laminoplasty are described. The device comprises of a plate with several holes that receive bone fasteners. The plate is curved at the ends to contour to the vertebral structure and has appendages to engage the displaced lamina in a fixed position. Alternatively, the plate has a bone fusion spacer in the middle to engage and fuse the lamina in the displaced position. Several methods of dynamically stabilizing the lamina after either the open door, double door or expansive laminoplasty technique are provided.

Abstract: The present invention relates to a craniotomy fixation device and method for fixing a bone flap to the skull following craniotomoy. The device may comprise two portions, one portion may be associated with the skull and the other portion may be associated with the bone flap. The two portions are connected in a way to accommodate changes in intracranial pressure.