Abstract: The present application relates to a cold plasma device (1) for treating skin (5). The cold plasma device (1) comprises a cold plasma generator (3) adapted to generate cold plasma that produces reactive species for treating said skin (5), and a manipulator (10) adapted to manipulate said skin (5) to increase exposure of bacteria on said skin to said reactive species during use of the device.

Abstract: The present invention relates to image analysis of pathology images. In order to improve reliability in image analysis of pathology images, a method is provided for providing support in identifying at least one feature of a tissue sample in a microscopic image.

Abstract: A method and system for processing a 3D tissue sample is provided, comprising the steps of receiving a tube with an inner space and two open ends, wherein the tube is configured to retain the 3D tissue sample in the inner space, arranging the tube so that one of the two open ends of the tube is located at a fluid channel, and forcing or actively pressing a tissue processing agent through the fluid channel and into the tube so that the tissue processing agent passes through the tissue.

Abstract: The present application relates to a cold plasma device (13) for treating a surface (6) with cold plasma. The device (13) has a cold plasma generator (14) adapted to generate cold plasma that produces reactive species for treating the surface (6). The device (13) also includes a treatment head (5) that is positionable relative to the surface (6) such that the reactive species are imparted toward the surface (6) during treatment. The device (13) is also provided with an air flow generator (8) to generate an air flow over the surface (6) and a controller (9) configured to control operation of the air flow generator (8) to generate an air flow over the surface (6) after the treatment has been completed such that remaining by-products of the cold plasma are dissipated.

Abstract: A method and a micro fluidic device comprising at least one micro fluidic structure for differential extraction of nuclear and extra-nuclear constituents of a single cell, said micro fluidic structure comprising a feeding channel for receiving a volume of a sample containing at least one cell, at least one trapping structure for capturing a single cell, and at least one output channel in fluid connection with the at least one trapping structure, wherein the at least one trapping structure extends from one side of the feeding channel substantially perpendicular to longitudinal axis of the feeding channel, the at least one trapping structure possessing an aperture at its end opposite to the fluid channel and in fluid communication with an output channel, said aperture being configured to provide a narrow section such that the nucleus of a cell captured in the trapping structure cannot pass through said narrow section into the output channel.

Abstract: The present invention relates to a microfluidic device suitable for accommodating, isolating, treating and/or processing cells. The device comprises an inlet chamber in fluid communication with at least one feeding channel being arranged in an essentially horizontal direction. The inlet chamber is suitable for receiving a volume of a liquid sample comprising at least one cell, and has an opening at its upward facing end which has a circular, ellipsoidal or polygonal cross-section. Further, the microfluidic device has a chute structure which defines a flow path for guiding the cells from the inlet chamber into the at least one feeding channel.

Abstract: The present application relates to a device for the electroporation of bacterial cells in or on a surface of the Stratum corneum layer of a person's skin. It comprises electrodes positionable in the vicinity of said surface; a generator to supply a voltage to the electrodes to generate an electrical field having a strength in the order of 25 to 35 KV/cm at said surface of the Stratum corneum layer to inactivate bacterial cells in or on said surface. The electrodes are configured so that the strength of the electrical field reduces as a function of the depth of penetration into the skin from 25 to 35 KV/cm at said surface to 3 KV/cm or less at a depth of penetration that does not exceed 15 microns.

Abstract: The present application relates to a cold plasma device (1) for treating skin (5). The cold plasma device (1) comprises a cold plasma generator (3) adapted to generate cold plasma that produces reactive species for treating said skin (5), and a manipulator (10) adapted to manipulate said skin (5) to increase exposure of bacteria on said skin to said reactive species during use of the device.

Abstract: The present application relates to a cold plasma device (13) for treating a surface (6) with cold plasma. The device (13) has a cold plasma generator (14) adapted to generate cold plasma that produces reactive species for treating the surface (6). The device (13) also includes a treatment head (5) that is positionable relative to the surface (6) such that the reactive species are imparted toward the surface (6) during treatment. The device (13) is also provided with an air flow generator (8) to generate an air flow over the surface (6) and a controller (9) configured to control operation of the air flow generator (8) to generate an air flow over the surface (6) after the treatment has been completed such that remaining by-products of the cold plasma are dissipated.

Abstract: The invention provides a microdermabrasion device (1) comprising a microdermabrasion zone (300) for abrading a part of a skin of a subject, wherein the microdermabrasion zone (300) comprises a support material (310) and abrasive structures (320) at least partially associated with the support material (310), wherein the microdermabrasion zone (300) comprises a releasable material (330), releasable comprised by the microdermabrasion zone (300), wherein the releasable material (330) is a solid in air at 20° C. and at 1 bar, and wherein the releasable material (330) comprises a functional material (1330).

Abstract: The present application relates to a device for the electroporation of bacterial cells in or on a surface of the Stratum corneum layer of a person's skin. It comprises electrodes positionable in the vicinity of said surface; a generator to supply a voltage to the electrodes to generate an electrical field having a strength in the order of 25 to 35 KV/cm at said surface of the Stratum corneum layer to inactivate bacterial cells in or on said surface. The electrodes are configured so that the strength of the electrical field reduces as a function of the depth of penetration into the skin from 25 to 35 KV/cm at said surface to 3 KV/cm or less at a depth of penetration that does not exceed 15 microns.