Patents by Inventor Roland Fabis

Roland Fabis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Porous ferro- or ferrimagnetic glass particles for isolating molecules
    Patent number: 7183002
    Abstract: Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules, under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use of identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
    Type: Grant
    Filed: March 22, 2001
    Date of Patent: February 27, 2007
    Assignee: Qiagen, GmbH
    Inventors: Philippe Sauer, Bernd Springer, Thomas Manz, Christoph Ritt, Roland Fabis
  • Methods for separating particulate substrates from solution while minimizing particle loss
    Publication number: 20040171077
    Abstract: The present invention provides a method for separation of a particulate matrix from a solution while reducing loss of particles during separation steps. Methods are also disclosed for isolation of molecules of interest using affinity particles or beads, wherein at least one step of the isolation is conducted in the presence of a detergent. The presence of detergent reduces the loss of matrix particles and enhances reproducibility and yield of the molecule of interest. The invention makes possible the manual and automated processing of affinity beads, especially magnetic beads, in multi-well as well as single-well vessels with significantly reduced bead loss, as compared with similar processes conducted in the absence of detergent.
    Type: Application
    Filed: February 27, 2004
    Publication date: September 2, 2004
    Inventors: Helge Lubenow, Kerstin Steinert, Roland Fabis, Joachim Ribbe, Melanie Emmerlich
  • Methods for separating particulate substrates from solution while minimizing particle loss
    Patent number: 6723510
    Abstract: The present invention provides a method for separation of a particulate matrix from a solution while reducing loss of particles during separation steps. Methods are also disclosed for isolation of molecules of interest using affinity particles or beads, wherein at least one step of the isolation is conducted in the presence of a detergent. The presence of detergent reduces the loss of matrix particles and enhances reproducibility and yield of the molecule of interest. The invention makes possible the manual and automated processing of affinity beads, especially magnetic beads, in multi-well as well as single-well vessels with significantly reduced bead loss, as compared with similar processes conducted in the absence of detergent.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: April 20, 2004
    Assignee: Qiagen GmbH
    Inventors: Helge Lubenow, Kerstin Steinert, Roland Fabis, Joachim Ribbe, Melanie Emmerlich
  • Use of alkanes for contamination-free purification or separation of biopolymers
    Patent number: 6706858
    Abstract: The present invention relates to the use of alkanes for the contamination-free purification or separation of biopolymers.
    Type: Grant
    Filed: October 22, 2002
    Date of Patent: March 16, 2004
    Assignee: Qiagen GmbH
    Inventors: Thomas Rothmann, Roland Fabis, Andreas Schäfer, Sabine Dorit Menzel, Thi My Chi Nguyen
  • Porous ferro-or ferrimagnetic glass particles for isolating molecules
    Publication number: 20030148101
    Abstract: Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules, under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use of identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
    Type: Application
    Filed: January 25, 2003
    Publication date: August 7, 2003
    Inventors: Philippe Sauer, Bernd Springer, Thomas Manz, Christoph Ritt, Roland Fabis
  • Use of alkanes for contamination-free purification or separation of biopolymers
    Publication number: 20030100705
    Abstract: The present invention relates to the use of alkanes for the contamination-free purification or separation of biopolymers.
    Type: Application
    Filed: October 22, 2002
    Publication date: May 29, 2003
    Inventors: Thomas Rothmann, Roland Fabis, Andreas Schafer, Sabine Dorit Menzel, Thi My Chi Nguyen
  • Use of alkanes for contamination-free purification or separation of biopolymers
    Publication number: 20030065152
    Abstract: The present invention relates to the use of alkanes for the contamination-free purification or separation of biopolymers.
    Type: Application
    Filed: May 10, 2002
    Publication date: April 3, 2003
    Inventors: Thomas Rothmann, Roland Fabis, Andreas Schafer, Sabine Dorit Menzel, Thi My Chi Nguyen
  • Methods for separating particulate substrates from solution while minimizing particle loss
    Publication number: 20010014466
    Abstract: The present invention provides a method for separation of a particulate matrix from a solution while reducing loss of particles during separation steps. Methods are also disclosed for isolation of molecules of interest using affinity particles or beads, wherein at least one step of the isolation is conducted in the presence of a detergent. The presence of detergent reduces the loss of matrix particles and enhances reproducibility and yield of the molecule of interest. The invention makes possible the manual and automated processing of affinity beads, especially magnetic beads, in multi-well as well as single-well vessels with significantly reduced bead loss, as compared with similar processes conducted in the absence of detergent.
    Type: Application
    Filed: March 20, 2001
    Publication date: August 16, 2001
    Inventors: Helge Lubenow, Kerstin Steinert, Roland Fabis, Joachim Ribbe, Melanie Emmerlich