Patents by Inventor Roland Schaefer
Roland Schaefer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240174683Abstract: The present invention relates to Map4K1 inhibitors of formula (I) (I), wherein A, E, G, Q, R1, R2 and R4 have the same meaning as defined in the description, to pharmaceutical compositions and combinations comprising the compounds according to the invention, and to the prophylactic and therapeutic use of the inventive compounds, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for neoplastic disorders, respectively cancer or conditions with dysregulated immune responses or other disorders associated with aberrant MAP4K1 signaling, as a sole agent or in combination with other active ingredients.Type: ApplicationFiled: February 4, 2022Publication date: May 30, 2024Applicants: Bayer Aktiengesellschaft, Deutsches KrebsforschungszentrumInventors: Ulrich LÜCKING, Jeffrey Stuart MOWAT, Ludwig ZORN, Lars WORTMANN, Steffen MÜLLER, Gabriele LEDER, Sandra BERNDT, Judith GÜNTHER, Lara KUHNKE, Antje Margret WENGNER, Rafael CARRETERO, Gerd WOHLFAHRT, Anders FRIBERG, Ulf BÖMER, Roland NEUHAUS, Maren OSMERS, Hideki Miyatake ONDOZABAL, Martina SCHÄFER, Louise EAGLING, Julien LEFRANC, Katrin NOWAK-REPPEL, Rienk OFFRINGA, Peng CHEN, Xuewei WANG, Yuanyuan YAN, Kai THEDE, Nikolay SITNIKOV, Berndt BUCHMANN, Dirk KOSEMUND, Detlef STOECKIGT
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Publication number: 20240108032Abstract: The present invention is directed to a feed additive comprising at least a fat-soluble vitamin and a process for its manufacture. Further objects of the present invention are feed comprising such feed additive, as well as methods for supplementation and corresponding uses of such feed additives and feed.Type: ApplicationFiled: October 12, 2020Publication date: April 4, 2024Inventors: Christian SCHAEFER, Roland SCHEX, Christos TSEKOU, Thomas ZWICK
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Publication number: 20240108044Abstract: The present invention relates to a powderous composition comprising at least one carotenoid and/or one carotenoid derivative, which can be produced easily and which can be used in many fields of application.Type: ApplicationFiled: February 8, 2022Publication date: April 4, 2024Inventors: Stefanie KIRCHEN, Thomas LINDEMANN, Christian SCHAEFER, Roland SCHEX, Thomas ZWICK
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Patent number: 11913945Abstract: Herein is reported a method for determining the concentration of a therapeutic antibody in a tissue of an experimental animal to whom the therapeutic antibody had been administered, wherein the interference from residual blood in a tissue sample of the experimental animal, which is used for determining the concentration of the therapeutic antibody in said tissue, is reduced by applying an inert reference antibody that does not penetrate into said tissue, whereby the inert reference antibody is administered 2 to 10 minutes prior to obtaining the tissue and blood sample.Type: GrantFiled: December 29, 2020Date of Patent: February 27, 2024Assignee: Hoffmann-La Roche Inc.Inventors: Martin Schaefer, Sylvia Rottach, Gregor Jordan, Kay-Gunnar Stubenrauch, Roland Staack, Kevin Brady
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Publication number: 20230091191Abstract: In a method for parameterising at least one device (30), at least one environmental value (31) of the device is determined via at least one sensor and/or an automation component. It is checked whether parameters are allocated to the at least one environmental value in a parameter database (32). If parameters are allocated to the at least one environmental value (31) in the parameter database (32), the device (30) is parameterised with parameters from the parameter database (32). If no parameters are allocated to the at least one environmental value (31) in the parameter database (32), the device (30) is parameterised with new parameters. The new parameters are then allocated (54) to the at least one environmental value (31) in the parameter database (32).Type: ApplicationFiled: September 20, 2022Publication date: March 23, 2023Inventors: Andrea Hiller-Brod, Albert Dorneich, Roland Schaefer, Stephan Langer, Heiko Mahr, Jochen Streib, Joerg Maier
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Publication number: 20220349793Abstract: Example networked material testing systems include: a database system storing a shared database, the shared database storing a material test procedure and material test result data; a first material test system communicatively coupled to the database system and configured to perform a first type of material test; and a second material test system communicatively coupled to the database system and configured to perform the first type of material test; wherein the database system comprises a computing device configured to execute machine readable instructions which cause the computing device to: transmit a first test program to the first material test system for performance of the first type of material test on a first specimen according to the first test program; store, in the shared database, first test result data received from the first material test system based on execution of the first test program; transmit a second test program to the second material test system for performance of the first type of matType: ApplicationFiled: April 29, 2022Publication date: November 3, 2022Inventors: Roland Schaefer, Sandra Straub, Matthias Pascher
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Patent number: 11435270Abstract: Hardness testers having a pivoting body and capable of providing power to accessories on the pivoting body are disclosed. An example hardness testing device includes: a rotating carriage configured to: hold at least one of an indenter or an objective and at least one accessory; and rotate to selectively place the at least one indenter or objective or the at least one accessory in an operative position to operate the at least one indenter or objective or the at least one accessory; a carriage mount configured to support the rotating carriage; and an electrical contact block mounted stationary with respect to the carriage mount, the electrical contact block comprising a plurality of electrical contacts configured to make electrical contact with a counterpart electrical contact block of the at least one accessory coupled to the rotating carriage when the at least one accessory is positioned in the operative position.Type: GrantFiled: April 23, 2019Date of Patent: September 6, 2022Assignee: ILLINOIS TOOL WORKS INC.Inventors: Rudolf Mathias Mayer, Markus Mueller, Roland Schaefer
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Publication number: 20220126418Abstract: An example grinder/polisher system includes: a specimen holder configured to secure a specimen; a platen; an actuator configured to move at least one of the specimen holder and the platen; a sensor configured to detect objects within a field of view of the sensor; and a controller configured to control movement of the actuator and to stop the actuator in response to detection of an object by the sensor while the actuator is moving.Type: ApplicationFiled: October 18, 2021Publication date: April 28, 2022Inventors: Roland Schaefer, Andrew Nocom
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Publication number: 20200278943Abstract: An interface (10) for an IO-Link master (20) has an IO-Link port transceiver, at least one wireless transceiver and a signal processing apparatus which is configured to provide a network between the IO-Link port transceiver and the at least one wireless transceiver. In a method for controlling an IO-Link system, a communication partner (30) communicates with at least one IO-Link device (40) via an interface (10). In a method for monitoring the IO-Link system, a communication flow between IO-Link ports (21, 22) of the IO-Link master (20) is stored in a storage element by means of the interface which is connected to the IO-Link master (20). The IO-Link master (20) has at least one IO-Link port (21) which is configured to be connected with an IO-Link port transceiver of the interfaces (10).Type: ApplicationFiled: February 10, 2020Publication date: September 3, 2020Inventors: Roland Schäfer, Pascal Gaggero, Stephan Langer, Roman Vracko
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Patent number: 10707920Abstract: Sensor apparatus (14) is provided, comprising a receiving device (20) by way of which the sensor apparatus (14) is wirelessly suppliable with electrical energy, a transmission device (44) by way of which data are wirelessly transmittable, a sensitive device (26), at least one data processing device (30) which is signal-operatively coupled to the sensitive device (26) and the transmission device (44) and which processes data of the sensitive device (26) and provides edited data as transmission data to the transmission device (44), and a device (52) for an interruption-tolerant operation of the sensor apparatus (14) with respect to the electrical energy supply, wherein the device (52) for an interruption-tolerant operation is realized by hardware and/or software of the sensor apparatus (14).Type: GrantFiled: October 2, 2018Date of Patent: July 7, 2020Assignee: BALLUFF GmbHInventors: Albert Dorneich, Roland Schaefer
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Publication number: 20200047299Abstract: Apparatus, systems, and/or methods for filtering, recapture, and/or recirculation of coolant are disclosed. In some examples, coolant (e.g., coolant fluid) is used to cool and/or clean a machine, such as a material removal machine, for example. In some examples, a recirculation tank may be in fluid communication with an inlet and/or outlet of a cabinet (and/or housing) of the machine. The recirculation tank may include a recapture reservoir having a filtering surface configured to prevent particulates, debris, and/or swarf from being recirculated with the coolant. A vibration device (e.g., a vibration motor and/or vibrating actuator), may be in contact with and/or configured to vibrate (and/or shake, rattle, oscillate, etc.) the filtering surface, recapture reservoir, and/or recirculation tank so as to keep the filter free from obstruction and/or help settle and/or compact filtered particulates in a bottom of the recapture reservoir and/or recirculation tank.Type: ApplicationFiled: July 3, 2019Publication date: February 13, 2020Inventors: Tony Emil Strombach, Roland Schaefer, Bryan John Kordus, Timothy Patrick Weber
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Patent number: 10469284Abstract: In an arrangement of an electrically communicative voltage supply for controlled operation of at least one electrically operable IO-Link device using an electrical DC voltage provided by a voltage supply unit as well as an IO-Link communication interface which is provided for the controlled operation of the at least one IO-Link device and formed with at least one channel, the IO-Link communication interface which is formed with at least one channel and the voltage supply unit form a structural unit and the IO-Link communication interface includes an IO-link master providing a gateway function.Type: GrantFiled: September 5, 2018Date of Patent: November 5, 2019Assignee: Balluff GmbHInventors: Albert Feinaeugle, Roland Schaefer
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Publication number: 20190323931Abstract: Hardness testers having a pivoting body and capable of providing power to accessories on the pivoting body are disclosed. An example hardness testing device includes: a rotating carriage configured to: hold at least one of an indenter or an objective and at least one accessory; and rotate to selectively place the at least one indenter or objective or the at least one accessory in an operative position to operate the at least one indenter or objective or the at least one accessory; a carriage mount configured to support the rotating carriage; and an electrical contact block mounted stationary with respect to the carriage mount, the electrical contact block comprising a plurality of electrical contacts configured to make electrical contact with a counterpart electrical contact block of the at least one accessory coupled to the rotating carriage when the at least one accessory is positioned in the operative position.Type: ApplicationFiled: April 23, 2019Publication date: October 24, 2019Inventors: Rudolf Mathias Mayer, Markus Mueller, Roland Schaefer
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Publication number: 20190140700Abstract: Sensor apparatus (14) is provided, comprising a receiving device (20) by way of which the sensor apparatus (14) is wirelessly suppliable with electrical energy, a transmission device (44) by way of which data are wirelessly transmittable, a sensitive device (26), at least one data processing device (30) which is signal-operatively coupled to the sensitive device (26) and the transmission device (44) and which processes data of the sensitive device (26) and provides edited data as transmission data to the transmission device (44), and a device (52) for an interruption-tolerant operation of the sensor apparatus (14) with respect to the electrical energy supply, wherein the device (52) for an interruption-tolerant operation is realized by hardware and/or software of the sensor apparatus (14).Type: ApplicationFiled: October 2, 2018Publication date: May 9, 2019Inventors: Albert Dorneich, Roland Schaefer
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Publication number: 20190074993Abstract: In an arrangement of an electrically communicative voltage supply for controlled operation of at least one electrically operable IO-Link device using an electrical DC voltage provided by a voltage supply unit as well as an IO-Link communication interface which is provided for the controlled operation of the at least one IO-Link device and formed with at least one channel, the IO-Link communication interface which is formed with at least one channel and the voltage supply unit form a structural unit and the IO-Link communication interface includes an IO-link master providing a gateway function.Type: ApplicationFiled: September 5, 2018Publication date: March 7, 2019Applicant: Balluff GmbHInventors: Albert FEINAEUGLE, Roland SCHAEFER
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Patent number: 10030213Abstract: The invention relates to a thickening concentrate for continuously producing a liquid cationic formulation of domestic cleaners or fabric softeners and to a method for continuously producing a liquid cationic formulation of domestic cleaners or fabric softeners, in which method a thickening concentrate according to the invention is used. The invention further relates to a formulation that can be obtained in accordance with the method according to the invention.Type: GrantFiled: August 25, 2016Date of Patent: July 24, 2018Assignee: Henkel AG & Co. KGaAInventors: Thomas Holderbaum, Roland Schaefer, Rainer Diedrich
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Patent number: 9604607Abstract: A method of controlling a vehicle includes providing a vehicle having a brake system configured to operate according to a nominal mode in which applied braking pressure is based on a driver braking request, a first active braking mode in which applied braking pressure is based on maximum ABS braking pressure and decreased in response to a driver brake pedal release, and a second active braking mode in which applied braking pressure is based on maximum braking pressure. In response to a detected collision, the system is controlled according to the first active braking mode. In response to the first active braking mode being active and no driver braking request being anticipated, the system is controlled according to the second active braking mode. In response to the first or second active braking modes being active and a termination criterion being satisfied, the system is controlled according to the nominal mode.Type: GrantFiled: October 30, 2015Date of Patent: March 28, 2017Assignee: FORD GLOBAL TECHNOLOGIES, LLCInventors: Hassen Hammoud, Jianbo Lu, Gilberto Burgio, Todd N. Clark, Otto Hofmann, Mohsen Lakehal-Ayat, Shweta M. Farmer, Jason Shomsky, Roland Schaefer
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Publication number: 20160362635Abstract: The invention relates to a thickening concentrate for continuously producing a liquid cationic formulation of domestic cleaners or fabric softeners and to a method for continuously producing a liquid cationic formulation of domestic cleaners or fabric softeners, in which method a thickening concentrate according to the invention is used. The invention further relates to a formulation that can be obtained in accordance with the method according to the invention.Type: ApplicationFiled: August 25, 2016Publication date: December 15, 2016Applicant: Henkel AG & Co. KGaAInventors: Thomas Holderbaum, Roland Schaefer, Rainer Diedrich
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Publication number: 20160046266Abstract: A method of controlling a vehicle includes providing a vehicle having a brake system configured to operate according to a nominal mode in which applied braking pressure is based on a driver braking request, a first active braking mode in which applied braking pressure is based on maximum ABS braking pressure and decreased in response to a driver brake pedal release, and a second active braking mode in which applied braking pressure is based on maximum braking pressure. In response to a detected collision, the system is controlled according to the first active braking mode. In response to the first active braking mode being active and no driver braking request being anticipated, the system is controlled according to the second active braking mode. In response to the first or second active braking modes being active and a termination criterion being satisfied, the system is controlled according to the nominal mode.Type: ApplicationFiled: October 30, 2015Publication date: February 18, 2016Inventors: Hassen HAMMOUD, Jianbo LU, Gilberto BURGIO, Todd N. CLARK, Otto HOFMANN, Mohsen LAKEHAL-AYAT, Shweta M. FARMER, Jason SHOMSKY, Roland SCHAEFER
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Patent number: 9205815Abstract: A method for controlling a vehicle braking system includes commanding vehicle brakes to provide braking torque based on a driver braking request in response to a detected collision and an anticipated application of a driver-actuated brake pedal after the collision. The method additionally includes activating the vehicle brakes in the absence of application of the brake pedal in response to a subsequent application and release of the brake pedal while a motion sensor reading exceeds a predefined threshold.Type: GrantFiled: September 18, 2014Date of Patent: December 8, 2015Assignee: Ford Global Technologies, LLCInventors: Hassen Hammoud, Jianbo Lu, Gilberto Burgio, Todd N. Clark, Otto Hofmann, Mohsen Lakehal-Ayat, Shweta M. Farmer, Jason Shomsky, Roland Schaefer