Patents by Inventor Rolf Pfirrmann

Rolf Pfirrmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100081649
    Abstract: A method of inhibiting growth of a tumor cell in a mammal may include steps of administering to the mammal a first solution including a tumor-inhibiting methylol-containing compound, the first solution further including a first combination having a plurality of physiologically acceptable electrolytes or a second combination having at least one amino acid in combination with at least one physiologically acceptable electrolyte. Alternatively, another solution may be administered to the mammal containing a tumor-inhibiting methylol-containing compound, while concurrently administering to the mammal a further solution including the first combination with the plurality of physiologically acceptable electrolytes or the second combination with at least one said amino acid in combination with at least one physiologically acceptable electrolyte.
    Type: Application
    Filed: December 22, 2005
    Publication date: April 1, 2010
    Applicant: Ed. Geistlich Soehne AG fuer chemische Industrie
    Inventor: Rolf Pfirrmann
  • Publication number: 20080114011
    Abstract: Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.
    Type: Application
    Filed: January 18, 2008
    Publication date: May 15, 2008
    Applicant: ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE
    Inventors: H. Redmond, Rolf Pfirrmann
  • Publication number: 20070275955
    Abstract: A method of treatment for preventing or reducing tumor growth in a patient includes administering to the patient an effective about of taurolidine, taurultam or a mixture thereof, so as to prevent or reduce the tumor growth in the patient.
    Type: Application
    Filed: February 2, 2007
    Publication date: November 29, 2007
    Applicant: Ed. Geistlich Soehne AG
    Inventor: Rolf PFIRRMANN
  • Publication number: 20070065400
    Abstract: Tumor metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of Interleukin-2 and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.
    Type: Application
    Filed: September 25, 2006
    Publication date: March 22, 2007
    Inventors: H. Redmond, Rolf Pfirrmann
  • Publication number: 20060199811
    Abstract: A method of treatment for preventing or reducing tumor growth in liver of a patient includes administering to the patient an effective about of taurolidine, taurultam or a mixture thereof, so as to prevent or reduce the tumor growth in the patient.
    Type: Application
    Filed: February 10, 2006
    Publication date: September 7, 2006
    Inventor: Rolf Pfirrmann
  • Publication number: 20060194796
    Abstract: A method of treatment for preventing or reducing tumor growth in liver of a patient includes administering to the patient an effective about of taurolidine, taurultam or a mixture thereof, so as to prevent or reduce the tumor growth in the patient.
    Type: Application
    Filed: February 9, 2006
    Publication date: August 31, 2006
    Inventor: Rolf Pfirrmann
  • Publication number: 20060160792
    Abstract: A method of inhibiting growth of a tumor cell in a mammal may include steps of administering to the mammal a first solution including a tumor-inhibiting methylol-containing compound, the first solution further including a first combination having a plurality of physiologically acceptable electrolytes or a second combination having at least one amino acid in combination with at least one physiologically acceptable electrolyte. Alternatively, another solution may be administered to the mammal containing a tumor-inhibiting methylol-containing compound, while concurrently administering to the mammal a further solution including the first combination with the plurality of physiologically acceptable electrolytes or the second combination with at least one said amino acid in combination with at least one physiologically acceptable electrolyte.
    Type: Application
    Filed: December 22, 2005
    Publication date: July 20, 2006
    Applicant: Ed. Geistlich Soehne AG fuer chemische Industrie
    Inventor: Rolf Pfirrmann
  • Publication number: 20050124609
    Abstract: Patients suffering from inflammatory bowel disease such as Crohn's disease or ulcerative colitis are treated either orally or intravenously with methylol transfer agents, such as taurolidine and/or taurultam. These agents can be used in combination with other drugs thereby allowing the use of smaller amounts of the other drugs and limiting unwanted side effects.
    Type: Application
    Filed: January 24, 2005
    Publication date: June 9, 2005
    Applicant: Ed. Geistlich Soehne AG
    Inventors: H. Redmond, Rolf Pfirrmann
  • Publication number: 20050124608
    Abstract: A method of inducing apoptotic death of a neoplastic cell, whereby the neoplastic cell is contacted with an apoptosis-inducing amount of a methylol-containing compound. This method is useful for treating both primary and metastatic cancers. A preferred embodiment includes administering a methylol transfer agent to the mammal, at a total daily dose of from about 2 g to about 60 g, the administration including at least two dosing cycles, each dosing cycle including an infusion phase of about 1 to 8 days, and a non-administration phase of about 1 to 14 days. Another embodiment includes treating liver cancer by administration of a solution of a methylol transfer agent directly to the liver via a hepatic vessel.
    Type: Application
    Filed: September 7, 2004
    Publication date: June 9, 2005
    Inventors: H. Redmond, Hanns Moehler, Ruediger Stendel, Rolf Pfirrmann
  • Publication number: 20050119254
    Abstract: A method of treating mesothelioma in a mammal, whereby a methylol-containing compound is administered to the mammal intrapleurally.
    Type: Application
    Filed: September 28, 2004
    Publication date: June 2, 2005
    Applicant: Ed. Geistlich Soehne AG
    Inventor: Rolf Pfirrmann
  • Publication number: 20050096314
    Abstract: A method of inhibiting growth of a tumor cell in a mammal may include steps of administering to the mammal a first solution including a tumor-inhibiting methylol-containing compound, the first solution further including a first combination having a plurality of physiologically acceptable electrolytes or a second combination having at least one amino acid in combination with at least one physiologically acceptable electrolyte. Alternatively, another solution may be administered to the mammal containing a tumor-inhibiting methylol-containing compound, while concurrently administering to the mammal a further solution including the first combination with the plurality of physiologically acceptable electrolytes or the second combination with at least one said amino acid in combination with at least one physiologically acceptable electrolyte.
    Type: Application
    Filed: September 28, 2004
    Publication date: May 5, 2005
    Applicant: Ed. Geistlich Soehne AG fuer chemische Industrie
    Inventor: Rolf Pfirrmann
  • Patent number: 4096241
    Abstract: This invention relates to novel preparations for the treatment and for prophylaxis of tooth and gum infections, and in particular parodontosis, comprising derivatives of thiadiazine as active ingredient. Pharmaceutical compositions according to the invention are described and exemplified.
    Type: Grant
    Filed: June 24, 1976
    Date of Patent: June 20, 1978
    Assignee: Ed. Geistlich Sohne A.G. fur Chemische Industrie
    Inventors: Peter Geistlich, Rolf Pfirrmann