Patents by Inventor Romain Remark

Romain Remark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOHISTOCHEMISTRY METHODS AND KIR3DL2-SPECIFIC REAGENTS
    Publication number: 20240117042
    Abstract: The present invention relates to antibodies and methods for detecting KIR3DL2 expression in paraffin-embedded tissue samples. Also provide are methods of making antibodies, antibody fragments, and derivatives thereof that specifically bind to their target antigen in paraffin-embedded tissue samples.
    Type: Application
    Filed: April 4, 2022
    Publication date: April 11, 2024
    Inventors: BENJAMIN ROSSI, STÉPHANIE CHANTEUX, ROMAIN REMARK, CÉCILE BONNAFOUS, CLARENCE DEFFAUD, THIBAUT PELAT
  • COMPOSITIONS AND METHODS FOR PREVENTING, DETECTING, AND TREATING INFLAMMATORY BOWEL DISEASE
    Publication number: 20230405086
    Abstract: The present disclosure relates to a composition comprising a post-translationally modified Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) protein. The disclosure further relates to methods of preventing or treating Crohn's Disease and/or a condition resulting from Crohn's Disease in a subject. The disclosure further relates to methods for diagnosing and/or predicting severity of and/or treating Crohn's Disease in a subject. Also disclosed are methods for diagnosing inflammatory bowel disease in a subject and methods for diagnosing a pre-disease state of Crohn's Disease in a subject.
    Type: Application
    Filed: April 30, 2021
    Publication date: December 21, 2023
    Applicants: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Sacha GNJATIC, Arthur MORTHA, Jean-Frederic COLOMBEL, Romain REMARK, Miriam MERAD
  • CELL SURFACE MICA AND MICB DETECTION USING ANTIBODIES
    Publication number: 20230296611
    Abstract: The present disclosure relates to research and diagnostic tools to specifically detect MICA and MICB polypeptides in paraffin embedded tissue samples. The disclosure also relates to methods of using the tools to detect MICA and MICB polypeptides, notably in tumor tissue.
    Type: Application
    Filed: August 6, 2021
    Publication date: September 21, 2023
    Inventors: MARION BENEZECH, ROMAIN REMARK
  • METHOD FOR THE PROGNOSIS OF SURVIVAL TIME OF A PATIENT SUFFERING FROM A SOLID CANCER
    Publication number: 20200041519
    Abstract: The present invention relates to an in vitro method for the prognosis of the survival time of a patient suffering from a solid cancer, comprising the quantification of the cell density of follicular B cells present in tumor-induced lymphoid structures from said patient, wherein a high density of follicular B cells indicates that the patient has a favorable prognosis and a low density of follicular B cells indicates that the patient has a poor prognosis.
    Type: Application
    Filed: September 17, 2019
    Publication date: February 6, 2020
    Inventors: Marie-Caroline Dieu-Nosjean, Wolf Herve Fridman, Romain Remark, Catherine Sautes-Fridman
  • TISSUE PROFILING USING MULTIPLEXED IMMUNOHISTOCHEMICAL CONSECUTIVE STAINING
    Publication number: 20190120845
    Abstract: The present invention relates to methods and compositions for sequential multidimensional immunohistochemical analyses of tissues.
    Type: Application
    Filed: April 17, 2017
    Publication date: April 25, 2019
    Inventors: Romain Remark, Miriam Merad, Sacha Gnjatic
  • METHOD FOR THE PROGNOSIS OF SURVIVAL TIME OF A PATIENT SUFFERING FROM A SOLID CANCER
    Publication number: 20150004253
    Abstract: The present invention relates to an in vitro method for the prognosis of the survival time of a patient suffering from a solid cancer, comprising the quantification of the cell density of follicular B cells present in tumor-induced lymphoid structures from said patient, wherein a high density of follicular B cells indicates that the patient has a favorable prognosis and a low density of follicular B cells indicates that the patient has a poor prognosis.
    Type: Application
    Filed: January 21, 2013
    Publication date: January 1, 2015
    Inventors: Marie-Caroline Dieu-Nosjean, Wolf Herve Fridman, Romain Remark, Catherine Sautes-Fridman