Abstract: Aspects of this disclosure relate to a combination of techniques and/or materials that can be used to form a synthetic scaffold for solid and/or hollow organs or tissue. In some embodiments, methods are provided that involve assembling a synthetic scaffold using a first material for a first structural component and a second material for a second structural component, in which the first or second structural component in a perfusion pathway. In some embodiments, materials (e.g. synthetic materials) for the scaffold are printed, molded, cast, polymerized or electrospun. In some embodiments, a scaffold may mimic a natural scaffold or several features of a natural scaffold.

Abstract: Aspects of this disclosure relate to a combination of techniques and/or materials that can be used to form a synthetic scaffold for solid and/or hollow organs or tissue. In some embodiments, methods are provided that involve assembling a synthetic scaffold using a first material for a first structural component and a second material for a second structural component, in which the first or second structural component in a perfusion pathway. In some embodiments, materials (e.g. synthetic materials) for the scaffold are printed, molded, cast, polymerized or electrospun. In some embodiments, a scaffold may mimic a natural scaffold or several features of a natural scaffold.

Abstract: Aspects of the invention relate to a combination of techniques and/or materials that can be used to form a synthetic scaffold for solid and/or hollow organs or tissue. In some embodiments, methods are provided that involve assembling a synthetic scaffold using a first material for a first structural component and a second material for a second structural component, in which the first or second structural component is a perfusion pathway. In some embodiments, materials (e.g., synthetic materials) for the scaffold are printed, molded, cast, polymerized, or electrospun. In some embodiments, a scaffold may mimic a natural scaffold or several features of a natural scaffold.

Abstract: Aspects of the disclosure relate to synthetic tissue or organ scaffolds and methods and compositions for promoting or maintaining their structural integrity. Aspects of the disclosure are useful to prevent scaffold damage (e.g., delamination) during or after implantation into a host. Aspects of the disclosure are useful to stabilize tissue or organ scaffolds that include electrospun fibers.

Abstract: Aspects of the disclosure relate to synthetic tissue or organ scaffolds and methods and compositions for promoting or maintaining their structural integrity. Aspects of the disclosure are useful to prevent scaffold damage (e.g., delamination) during or after implantation into a host. Aspects of the disclosure are useful to stabilize tissue or organ scaffolds that include electrospun fibers.

Abstract: Aspects of the disclosure relate to synthetic tissue or organ scaffolds and methods and compositions for promoting or maintaining their structural integrity. Aspects of the disclosure are useful to prevent scaffold damage (e.g., delamination) during or after implantation into a host. Aspects of the disclosure are useful to stabilize tissue or organ scaffolds that include electrospun fibers.

Abstract: A method of manufacturing a product at or on-route to a point of delivery in order to eliminate shipments of pre-made products from remote manufacturing sites are implemented through a manned or unmanned transportation vehicle, a multi-axis printer (with the necessary servo mechanisms or services to complete the product), and a central computing device. The transportation vehicle provides the mean of transportation to the multi-axis printer from one location to another as the multi-axis printer is able to output a final product in accordance to consumer requirements. The central computing device is communicably coupled with the multi-axis printer and the transportation vehicle to execute a manufacture request that provides the specifications of the final product. Once the final product is constructed, the multi-axis printer performs at least one reliability test for the final product to insure the proper functionality and the structural integrity of the final product.

Abstract: Aspects of the invention relate to a combination of techniques and/or materials that can be used to form a synthetic scaffold for solid and/or hollow organs or tissue. In some embodiments, methods are provided that involve assembling a synthetic scaffold using a first material for a first structural component and a second material for a second structural component, in which the first or second structural component is a perfusion pathway. In some embodiments, materials (e.g., synthetic materials) for the scaffold are printed, molded, cast, polymerized, or electrospun. In some embodiments, a scaffold may mimic a natural scaffold or several features of a natural scaffold.

Abstract: Aspects of the disclosure provide techniques for detecting differences and/or changes in biological and non-biological material using infrared imaging. Aspects of the disclosure are useful for monitoring and evaluating synthetic scaffolds and engineered tissue and organs for tissue engineering and transplantation.

Abstract: According to some aspects, tissue scaffolds are provided that comprise one or more types of nanofibers. In some embodiments, one or more design features are incorporated into a tissue scaffold (e.g.

Abstract: Aspects of the invention relate to methods and devices for evaluating tissue injuries. In some embodiments, the invention provides methods and devices for evaluating tissue injuries based on infrared emission spectra and/or emission levels from injured tissue. In some embodiments, the invention provides methods and devices for evaluating skin injuries (e.g., skin burns) and for targeting treatment delivery to injuries including skin injuries.

Abstract: Aspects of the disclosure relate to synthetic tissue or organ scaffolds and methods and compositions for promoting or maintaining their structural integrity. Aspects of the disclosure are useful to prevent scaffold damage (e.g., delamination) during or after implantation into a host. Aspects of the disclosure are useful to stabilize tissue or organ scaffolds that include electrospun fibers.

Abstract: Aspects of the disclosure provide techniques for detecting differences and/or changes in biological and non-biological material using infrared imaging. Aspects of the disclosure are useful for monitoring and evaluating synthetic scaffolds and engineered tissue and organs for tissue engineering and transplantation.

Abstract: Articles and methods for growing or analyzing tissues and organs using bioreactors or other devices and components are provided. In some embodiments, a bioreactor is configured to provide a growth chamber having one or more inlets, outlets, sensors, organ attachment sites, and/or organ identifiers.

Abstract: The present invention relates to methods and devices for maintaining cellular viability and function for therapeutic purposes. The invention provides methods and devices for maintaining the proliferative and developmental potential of cellular preparations by protecting the from physical and physiological damage during storage, preparation, and delivery to a site (e.g., a tissue site). The invention also provides methods and devices for evaluating tissues and organs, and selecting appropriate sites for cellular delivery.

Abstract: This invention relates to equilibrium dialysis systems and methods. More particularly, the invention relates to pre-assembled or ready-to-use single-well or multi-well dialysis systems that are disposable in their entirety, comprising a molded block for performing equilibrium dialysis of one or more samples. Such equilibrium dialysis systems can be used for protein binding assays, molecule-molecule interaction studies, tissue cultures and many other biological and chemical applications. Such equilibrium dialysis systems are suitable for use in manual or high throughput formats.