Patents by Inventor Ronald A. Mickaels

Ronald A. Mickaels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gravitational attractor engine for adaptively autoclustering n-dimensional datastreams
    Patent number: 5795727
    Abstract: This invention relates to a method for autoclustering N-dimensional datastreams. The invention has particular utility in analyzing multi-parameter data from a flow cytometer, and more particularly has utility in analyzing data from whole blood cells tagged with fluorescently labelled CD3, CD4 and CD8 monoclonal antibodies to which a known number of fluorescent microbeads has been added.
    Type: Grant
    Filed: May 6, 1996
    Date of Patent: August 18, 1998
    Assignee: Becton Dickinson and Company
    Inventors: Pierre Bierre, Ronald A. Mickaels
  • Flow cytometric method for autoclustering cells
    Patent number: 5627040
    Abstract: This invention relates to a method for autoclustering N-dimensional datastreams. The invention has particular utility in analyzing multi-parameter data from a flow cytometer, and more particularly has utility in analyzing data from whole blood cells tagged with fluorescently labelled CD3, CD4 and CD8 monoclonal antibodies to which a known number of fluorescent microbeads has been added.
    Type: Grant
    Filed: April 26, 1993
    Date of Patent: May 6, 1997
    Assignee: Becton Dickinson and Company
    Inventors: Pierre Bierre, Ronald A. Mickaels
  • Method for data transformation
    Patent number: 5224058
    Abstract: A method for the non-linear, non-logrithmic transformation of one or more parameters of data gathered by means of flow cytometry is disclosed wherein the method seeks to maximize the resolution between populations of interest for each parameter while maintaining the dynamic range of the data recorded.
    Type: Grant
    Filed: May 1, 1990
    Date of Patent: June 29, 1993
    Assignee: Becton, Dickinson and Company
    Inventors: Ronald A. Mickaels, Richard K. Dost, Leon W. M. M. Terstappen, Michael R. Loken