Patents by Inventor Ronald Chatelier
Ronald Chatelier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190360019Abstract: Disclosed herein are methods and products for the incorporation of an enzyme mediated reaction step and/or cascading amplification methods that are activated via a molecule cleavage event and methods and products for cleavage detection in assays where a binding event can be used to selectively detect the analyte of interest.Type: ApplicationFiled: November 16, 2017Publication date: November 28, 2019Inventors: Alastair M. HODGES, Ronald CHATELIER
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Publication number: 20190265185Abstract: The instant invention relates to solutions and methods that can be used to present the user of an analyser with a test result without resorting to human blood or plasma and thereby overcoming the disadvantages of using blood or plasma each time an analyser is to be used. In some embodiments, a solution for use with one or more blood coagulation sensor substrates to generate a signal relating to the clot time is provided, wherein the solution is non-biohazardous.Type: ApplicationFiled: October 20, 2017Publication date: August 29, 2019Inventors: Ronald CHATELIER, Peter Michael RONALD
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Patent number: 9863942Abstract: Disclosed herein are methods and devices for detecting the presence of an analyte of interest. A biosensor device can include a reaction chamber and an electrochemical detection chamber. The reaction chamber can include at least one immobilized binding site and a probe conjugate adapted to bind to at least one of the target analyte and the immobilized binding site while the detection chamber can include electrodes for detecting an electrochemical reaction. If present, the target analyte in the fluid sample results in a change in the amount of probe conjugate bound in the reaction chamber, which can be detected electrochemically in the detection chamber.Type: GrantFiled: September 18, 2009Date of Patent: January 9, 2018Assignee: Universal Biosensors Pty LtdInventors: Alastair McIndoe Hodges, Ronald Chatelier, Dennis Rylatt
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Patent number: 7749371Abstract: Methods and apparatus for electrochemically determining an analyte concentration value in a physiological sample are disclosed. The methods include using a test strip in which two time-current transients are measured by a meter electrically connected to an electrochemical test strip. Integrative current values are derived from the time-current transients and used in the calculation of analyte concentration.Type: GrantFiled: September 30, 2005Date of Patent: July 6, 2010Assignee: LifeScan, Inc.Inventors: Sherry Guo, Alastair Hodges, Ronald Chatelier, Bin Zhang
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Publication number: 20100006452Abstract: Disclosed herein are methods and devices for detecting the presence of an analyte of interest. A biosensor device can include a reaction chamber and an electrochemical detection chamber. The reaction chamber can include at least one immobilized binding site and a probe conjugate adapted to bind to at least one of the target analyte and the immobilized binding site while the detection chamber can include electrodes for detecting an electrochemical reaction. If present, the target analyte in the fluid sample results in a change in the amount of probe conjugate bound in the reaction chamber, which can be detected electrochemically in the detection chamber.Type: ApplicationFiled: September 18, 2009Publication date: January 14, 2010Applicant: UNIVERSAL BIOSENSORS PTY LTD.Inventors: Alastair McIndoe Hodges, Ronald Chatelier, Dennis Rylatt
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Publication number: 20080121533Abstract: The present invention provides a metal electrode stabilised by a coating, the coating comprising a sulfur containing moiety in its molecular structure. The coating may also include a hydrophilic group and a spacer between the sulfur containing moiety and the hydrophilic group. Preferably, the sulfur containing moiety is selected from the group comprising thiol, disulfide and SOx, and the hydrophilic group is selected from the group comprising hydroxyl, amine, carboxyl, carbonyl, oligo (ethylene oxide) chain, and zwitterionic species. Compounds useful in the present invention include 2-mercaptoethanol, 2-mercaptoethylamine, 3-mercaptopropionic acid, thiophene, 4-carboxythiophene, cysteine, homocysteine, and cystine.Type: ApplicationFiled: October 29, 2007Publication date: May 29, 2008Applicant: LifeScan, Inc.Inventors: Alastair Hodges, Ronald Chatelier
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Publication number: 20080081976Abstract: The invention disclosed in this application is a method and device for combining the sampling and analyzing of sub-dermal fluid samples, e.g., interstitial fluid or whole blood, in a device suitable for hospital bedside and home use. It is applicable to any analyte that exists in a usefully representative concentration in the fluid, and is especially suited to the monitoring of glucose.Type: ApplicationFiled: October 29, 2007Publication date: April 3, 2008Applicant: LifeScan, Inc.Inventors: Alastair Hodges, Ronald Chatelier, Garry Chambers
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Publication number: 20080073207Abstract: Mediator stabilized reagent compositions and methods for their use in electrochemical analyte determination assays are provided. The subject reagent compositions include an enzyme, a redox mediator and a mediator-stabilizing buffer. Optionally, the reagent compositions may further include one or more of a wetting agent, detergent, enzyme cofactor and combinations thereof. Also provided are electrochemical test strips that include the subject reagent compositions, systems and kits that include the same as well as methods for using the same in analyte detection assays. The subject invention finds use in a variety of different applications, including glucose concentration determination applications.Type: ApplicationFiled: October 31, 2007Publication date: March 27, 2008Inventors: Maria Teodorczyk, Ronald Chatelier, Alastair Hodges, Timothy Ohara, Remy Dato
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Patent number: 7335292Abstract: The present invention provides a metal electrode stabilized by a coating, the coating comprising a sulfur containing moiety in its molecular structure. The coating may also include a hydrophilic group and a spacer between the sulfur containing moiety and the hydrophilic group. Preferably, the sulphur-containing moiety is selected from the group comprising thiol, disulphide and SOx, and the hydrophilic group is selected from the group comprising hydroxyl, amine, carboxyl, carbonyl, oligo (ethylene oxide) chain, and zwitterionic species. Compounds useful in the present invention include 2-mercaptoethanol, 2-mercaptoethylamine, 3-mercaptopropionic acid, thiophene, 4-carboxythiophene, cysteine, homocysteine, and cystine.Type: GrantFiled: July 29, 2003Date of Patent: February 26, 2008Assignee: LifeScan, Inc.Inventors: Alastair McIndoe Hodges, Ronald Chatelier
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Publication number: 20070227912Abstract: Disclosed herein are methods and apparatus for determining analyte concentration in a rapid and accurate manner. The methods include depositing a physiological sample in an electrochemical cell and finding a first and second current transient. Peak current values are obtained from the first and second peak current values and used to reduce the influence of interferents in a current value. Based on this “corrected” current value, an accurate analyte concentration can be determined.Type: ApplicationFiled: March 31, 2006Publication date: October 4, 2007Applicant: LifeScan, Inc.Inventors: Ronald Chatelier, Alastair Hodges, Bruce Verity
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Publication number: 20070074977Abstract: Methods and apparatus for electrochemically determining an analyte concentration value in a physiological sample are disclosed. The methods include using a test strip in which two time-current transients are measured by a meter electrically connected to an electrochemical test strip. Integrative current values are derived from the time-current transients and used in the calculation of analyte concentration.Type: ApplicationFiled: September 30, 2005Publication date: April 5, 2007Applicant: LifeScan, Inc.Inventors: Sherry Guo, Alastair Hodges, Ronald Chatelier, Bin Zhang
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Publication number: 20070017805Abstract: The invention disclosed in this application is a method and device for combining the sampling and analyzing of sub-dermal fluid samples, e.g., interstitial fluid or whole blood, in a device suitable for hospital bedside and home use. It is applicable to any analyte that exists in a usefully representative concentration in the fluid, and is especially suited to the monitoring of glucose.Type: ApplicationFiled: June 30, 2006Publication date: January 25, 2007Applicant: LifeScan, Inc.Inventors: Alastair Hodges, Ronald Chatelier, Garry Chambers
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Publication number: 20060237332Abstract: There is disclosed a method of measuring formation of a barrier to restrict or reduce movement of an electroactive species. The method comprises providing an electrochemical cell (1, 2, 3) having a working electrode (23, 24) and a counter electrode (23, 24) spaced from the working electrode, providing a subject component, a testing component and at least one electroactive species within the cell, the subject and testing components being intended to cause the formation of a barrier to restrict or reduce movement of an electroactive species, applying a potential between the working electrode and the counter electrode sufficient to produce a current proportional to the concentration of the electroactive species being measured, and measuring the current at the working electrode to obtain a measure of the formation of the barrier to restrict or reduce movement of the electroactive species.Type: ApplicationFiled: January 16, 2004Publication date: October 26, 2006Applicant: Universal Biosensors PYT LimitedInventors: Alastair Hodges, Ronald Chatelier
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Publication number: 20060134713Abstract: Disclosed herein are methods and devices for detecting the presence of an analyte of interest. A biosensor device can include a reaction chamber and an electrochemical detection chamber. The reaction chamber can include at least one immobilized binding site and a probe conjugate adapted to bind to at least one of the target analyte and the immobilized binding site, while the detection chamber can include electrodes for detecting an electrochemical reaction. If present, the target analyte in the fluid sample results in a change in the amount of probe conjugate bound in the reaction chamber, which can be detected electrochemically in the detection chamber.Type: ApplicationFiled: November 21, 2005Publication date: June 22, 2006Applicant: LifeScan, Inc.Inventors: Dennis Rylatt, Alastair Hodges, Ronald Chatelier
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Publication number: 20040069657Abstract: The present invention provides a metal electrode stabilised by a coating, the coating comprising a sulfur containing moiety in its molecular structure. The coating may also include a hydrophilic group and a spacer between the sulfur containing moiety and the hydrophilic group. Preferably, the sulphur-containing moiety is selected from the group comprising thiol, disulphide and SOx, and the hydrophilic group is selected from the group comprising hydroxyl, amine, carboxyl, carbonyl, oligo (ethylene oxide) chain, and zwitterionic species. Compounds useful in the present invention include 2-mercaptoethanol, 2-mercaptoethylamine, 3-mercaptopropionic acid, thiophene, 4-carboxythiophene, cysteine, homocysteine, and cystine.Type: ApplicationFiled: July 29, 2003Publication date: April 15, 2004Applicant: LifeScan, Inc.Inventors: Alastair Hodges, Ronald Chatelier
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Patent number: 6652734Abstract: The present invention provides a metal electrode stabilised by a coating, the coating comprising a sulfur containing moiety in its molecular structure. The coating may also include a hydrophilic group and a spacer between the sulfur containing moiety and the hydrophilic group. Preferably, the sulfur containing moiety is selected from the group comprising thiol, disulfide and SOx, and the hydrophilic group is selected from the group comprising hydroxyl, amine, carboxyl, carbonyl, oligo (ethylene oxide) chain, and zwitterionic species. Compounds useful in the present invention include 2-mercaptoethanol, 2-mercaptoethylamine, 3-mercaptopropionic acid, thiophene, 4-carboxythiophene, cysteine, homocysteine, and cystine.Type: GrantFiled: September 19, 2000Date of Patent: November 25, 2003Assignee: LifeScan, Inc.Inventors: Alastair Hodges, Ronald Chatelier
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Publication number: 20030180814Abstract: This invention describes a quantitative, inexpensive, disposable immunosensor that requires no wash steps and thus generates no liquid waste. Moreover, in preferred embodiments of the sensor no timing steps are required of the user, and the sensor can be readily adapted to antigen-antibody interactions over a wide kinetic range.Type: ApplicationFiled: March 21, 2002Publication date: September 25, 2003Inventors: Alastair Hodges, Ronald Chatelier