Abstract: A ball valve for a ball valve assembly having a housing with a housing sealing surface configured to selectively seal against the ball valve. The ball valve includes an outer sealing surface configured to selectively seal against the housing sealing surface, and a recessed surface set inward of the outer sealing surface and defining a reservoir within the outer sealing surface. As the ball valve rotates between open and closed positions, the reservoir establishes a gap between the recessed surface and the housing sealing surface that enables debris to pass therethrough and facilitate preventing debris accumulation between the ball valve and the housing sealing surface.

Abstract: The present invention relates to novel antitumor depsipeptides produced by Micromonospora strain 39500, ATCC 55011, and having the structural formula ##STR1## wherein R.sub.1 is 2-methylpropanoyl, and R.sub.2 is 2-methylppropanoyl, propanoyl or acetyl; or R.sub.1 is 3-methylbutanoyl, and R.sub.2 is 2-methylpropanoyl or 3-methylbutanoyl; or R.sub.1 is propanoyl, and R.sub.2 is acetyl or propanoyl.

Abstract: An antibiotic designated BMY-42448 is produced by fermentation of Micromonospora narashinoensis strain C39217-R109-7 (ATCC-53791). BMY-42448 exhibits both in vitro and in vivo antitumor activity.

Abstract: A new antibiotic designated BMY-42448 is produced by fermentation of Micromonospora narashinoensis strain C39217-R109-7 (ATCC-53791). BMY-42448 exhibits both in vitro and in vivo antitumor activity.

Abstract: A pet litter box, including a device for locking the box after it has been used and re-closed, is formed from a single foldable blank. When the box is closed or re-closed it has inter-laying first and second halves, each having bottom and sidewall portions. The halves are connected to one another by a joining portion, and joining sidewalls. Each of the sidewalls of the first half carries a tab. The sidewall portions of the second half each define a diagonal crease, and the pair of joining side-wall portions each define a diagonal crease and a pair of vertical creases. When the box is fully open its first, second and joining portions define an open tray. After the system has been used the box can be re-closed and locked. During re-closing the joining sidewall portions and the two sidewalls of the second half all fold inwardly at their creases, thereby forming a pair of slots between the pairs of creases on each side.