Abstract: A method of identifying a compound capable of reducing or preventing prolonged sensory neuron hyper-excitability comprising the steps of: (a) administering the compound to an experimental non-human animal having prolonged sensory neuron hyper-excitability; (b) generating an expression profile of the genes modulated in the Nodose Ganglia (NG) of the animal of step (a); (c) comparing the expression profile obtained in (b) with the expression profile of a corresponding panel of genes expressed in the NG of an experimental non-human animal having no prolonged sensory neuron hyper-excitability; wherein a positive correlation of the expression profiles is indicative that the compound is capable of reducing or preventing prolonged sensory neuron hyper-excitability in NG.

Abstract: A sample, or slide, retaining tray includes a reagent reservoir, or recess, and a reaction chamber. A slide, or other sample container, can be positioned on the sample retaining tray as desired, with a tissue specimen face down, between a platen on the tray and the slide. A reagent from the reservoir is rendered flowable, such as by heating, and flows from the reservoir into the reaction chamber. Optionally, reagents or other fluids can be provided from above, by dripping onto a drip surface of the sample retaining tray, or below via an inlet port in the platen.

Abstract: An air filtration and aromatizer apparatus which includes a housing, a motor in the housing with a fan for drawing air through an inlet toward an outlet through a pollution-collecting chamber, and an elongated hollow tubular perforated member having an upper end connected to the motor output shaft and a lower end disposed in a bath of water. The hollow tubular member is formed in such a manner that as it is rotated by the motor, it draws water from the container under the influence of centrifugal force, and then forces the water through the perforations to form a mist or rain-like atmosphere in the path of motion of the air passing from the housing inlet toward the housing outlet.

Abstract: A boiler comprises a shell for fluid to be treated and divided into first and second heat exhange zones by at least one baffle, the zones being in communication with one another beneath a lower end of the baffle. Exhaust gases from a combustion source are supplied to a plurality of heat exchange tubes extending through each zone in heat exchange relationship with the fluid in the shell and being arranged in passes sequentially connected to one another whereby the exhaust gases pass sequentially through the first and second zones. The fluid to be heated is fed to an upper region of the second zone such that the temperature of gases passing through at least some of the tubes in the second zone falls to below the dew points of combustion products therein, the tubes in which condensation occurs being orientated such that condensates flow therefrom for disposal.