Patents by Inventor Ronald T. Riley

Ronald T. Riley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination
    Patent number: 6720184
    Abstract: This invention provides a method of altering the metabolism of sphingolipids in a cell comprising contacting the cell with a fumonisin, or an analog thereof. The invention also provides a method of detecting the consumption of a fumonisin or a fumonisin analog in a subject comprising (A) detecting, in a sample from the subject, the state of the metabolic pathway of sphingolipids and (B) comparing the state of the metabolic pathway to that of a normal subject, the presence of a change in the state of the metabolic pathway indicating the consumption of a fumonisin or a fumonisin analog. Also provided is a method of detecting the presence of a fumonisin or fumonisin analog contamination in a sample from a food or feed comprising detecting a reaction of the metabolic pathway of sphingolipids, the presence of the reaction indicating the presence of a fumonisin or fumonisin analog contamination. Furthermore, novel fumonisin analogs and compositions comprising fumonisins and fumonisin analogs are provided.
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: April 13, 2004
    Assignee: Emory University
    Inventors: Alfred H. Merrill, Jr., Elaine W. Wang, Dennis C. Liotta, Ronald T. Riley
  • Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination
    Patent number: 6127578
    Abstract: This invention provides a method of altering the metabolism of sphingolipids in a cell comprising contacting the cell with a fumonisin, or an analog thereof. The invention also provides a method of detecting the consumption of a fumonisin or a fumonisin analog in a subject comprising (A) detecting, in a sample from the subject, the state of the metabolic pathway of sphingolipids and (B) comparing the state of the metabolic pathway to that of a normal subject, the presence of a change in the state of the metabolic pathway indicating the consumption of a fumonisin or a fumonisin analog. Also provided is a method of detecting the presence of a fumonisin or fumonisin analog contamination in a sample from a food or feed comprising detecting a reaction of the metabolic pathway of sphingolipids, the presence of the reaction indicating the presence of a fumonisin or fumonisin analog contamination. Furthermore, novel fumonisin analogs and compositions comprising fumonisins and fumonisin analogs are provided.
    Type: Grant
    Filed: April 4, 1996
    Date of Patent: October 3, 2000
    Assignees: Emory University, The United States of America as represented by the Secretary of Agriculture
    Inventors: Alfred H. Merrill, Jr., Elaine W. Wang, Dennis C. Liotta, Ronald T. Riley
  • Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination
    Patent number: 5518879
    Abstract: This invention provides a method of altering the metabolism of sphingolipids in a cell comprising contacting the cell with a fumonisin, or an analog thereof. The invention also provides a method of detecting the consumption of a fumonisin or a fumonisin analog in a subject comprising (A) detecting, in a sample from the subject, the state of the metabolic pathway of sphingolipids and (B) comparing the state of the metabolic pathway to that of a normal subject, the presence of a change in the state of the metabolic pathway indicating the consumption of a fumonisin or a fumonisin analog. Also provided is a method of detecting the presence of a fumonisin or fumonisin analog contamination in a sample from a food or feed comprising detecting a reaction of the metabolic pathway of sphingolipids, the presence of the reaction indicating the presence of a fumonisin or fumonisin analog contamination. Furthermore, novel fumonisin analogs and compositions comprising fumonisins and fumonisin analogs are provided.
    Type: Grant
    Filed: April 2, 1993
    Date of Patent: May 21, 1996
    Assignees: Emory University, The United States of America as represented by the Secretary of Agriculture
    Inventors: Alfred H. Merrill, Jr., Elaine W. Wang, Ronald T. Riley
  • Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination
    Patent number: 5232837
    Abstract: This invention provides a method of altering the metabolism of sphingolipids in a cell comprising contacting the cell with a fumonisin, or an analog thereof. The invention also provides a method of detecting the consumption of a fumonisin or a fumonisin analog in a subject comprising (A) detecting, in a sample from the subject, the state of the metabolic pathway of sphingolipids and (B) comparing the state of the metabolic pathway to that of a normal subject, the presence of a change in the state of the metabolic pathway indicating the consumption of a fumonisin or a fumonisin analog. Also provided is a method of detecting the presence of a fumonisin or fumonisin analog contamination in a sample from a food or feed comprising detecting a reaction of the metabolic pathway of sphingolipids, the presence of the reaction indicating the presence of a fumonisin or fumonisin analog contamination. Furthermore, novel fumonisin analogs and compositions comprising fumonisins and fumonisin analogs are provided.
    Type: Grant
    Filed: August 5, 1991
    Date of Patent: August 3, 1993
    Assignees: Emory University, The United States of America as represented by the Secretary of Agriculture
    Inventors: Alfred H. Merrill, Jr., Elaine W. Wang, Dennis C. Liotta, Ronald T. Riley