Patents by Inventor Ronald T. Wester

Ronald T. Wester has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines
    Patent number: 6147090
    Abstract: Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: November 14, 2000
    Assignee: Pfizer Inc.
    Inventors: Michael P. DeNinno, Christian J. Mularski, Roger B. Ruggeri, Ronald T. Wester
  • Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines
    Patent number: 6147089
    Abstract: Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: November 14, 2000
    Assignee: Pfizer Inc.
    Inventors: Michael P. DeNinno, Roger B. Ruggeri, Ronald T. Wester
  • Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines
    Patent number: 6140342
    Abstract: Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: October 31, 2000
    Assignee: Pfizer Inc.
    Inventors: Steven W. Goldstein, Michael R. Makowski, Roger B. Ruggeri, Ronald T. Wester
  • 4-amino substituted-2-substituted-1,2,3,4-tetrahydroquinolines
    Patent number: 6140343
    Abstract: Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: October 31, 2000
    Assignee: Pfizer
    Inventors: Michael P. DeNinno, George T. Magnus-Aryitey, Roger B. Ruggeri, Ronald T. Wester
  • Phosphorus containing renin inhibitors
    Patent number: 5468732
    Abstract: Phosphorus containing polypeptides as renin inhibitors, useful as antihypertensive agents.
    Type: Grant
    Filed: August 2, 1991
    Date of Patent: November 21, 1995
    Assignee: Pfizer Inc.
    Inventor: Ronald T. Wester
  • Angiotensin II receptor antagonists
    Patent number: 5338740
    Abstract: The present invention relates to novel heterocyclic derivatives of the formulaAr--W--Hetwherein Ar, W and Het are as defined below, and related compounds, pharmaceutical compositions comprising such compounds, and the use of such compounds as regulators of the action of angiotensin II in mammals. The compounds of this invention are useful in the treatment and prevention of hypertension, glaucoma, renal disease, congestive heart failure, cognitive dysfunction, and other conditions in which the action of angiotensin II is implicated. This invention also relates to pharmaceutical compositions containing these compounds and to methods of inhibiting angiotensin II in mammals by administration of such compounds.
    Type: Grant
    Filed: July 13, 1993
    Date of Patent: August 16, 1994
    Assignee: Pfizer Inc.
    Inventors: Philip C. Carpino, Ronald T. Wester, Paul A. Da Silva Jardine
  • Nor-statine and nor-cyclostatine polypeptides
    Patent number: 5034376
    Abstract: Polypeptides and derivatives thereof containing nor-statine and nor-cyclostatine are useful for inhibiting the angiotensinogen-cleaving action of the enzyme renin.
    Type: Grant
    Filed: March 21, 1990
    Date of Patent: July 23, 1991
    Assignee: Pfizer Inc.
    Inventors: Dennis J. Hoover, Robert L. Rosati, Ronald T. Wester
  • Nor-statine and nor-cyclostatine polypeptides
    Patent number: 4935405
    Abstract: Polypeptides and derivatives thereof containing nor-statine and nor-cyclostatine are useful for inhibiting the angiotensinogen-cleaving action of the enzyme renin.
    Type: Grant
    Filed: November 29, 1988
    Date of Patent: June 19, 1990
    Assignee: Pfizer Inc.
    Inventors: Dennis J. Hoover, Robert L. Rosati, Ronald T. Wester
  • Nor-statine and nor-cyclostatine polypeptides
    Patent number: 4814342
    Abstract: Polypeptides and derivatives thereof containing nor-statine and nor-cyclostatine are useful for inhibiting the angiotensinogen-cleaving action of the enzyme renin.
    Type: Grant
    Filed: October 23, 1987
    Date of Patent: March 21, 1989
    Assignee: Pfizer Inc.
    Inventors: Dennis J. Hoover, Robert L. Rosati, Ronald T. Wester