Patents by Inventor Ronen Shemesh

Ronen Shemesh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220048972
    Abstract: This invention relates to LY6G6F, VSIG10, TMEM25 and LSR proteins, which are suitable targets for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders, and drug development. This invention further relates to soluble LY6G6F, VSIG10, TMEM25 and LSR molecules, extracellular domains of LY6G6F, VSIG10, TMEM25 and LSR and conjugates, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders. This invention further relates to antibodies and antigen binding fragments and conjugates containing same, and/or alternative scaffolds, specific for LY6G6F, VSIG10, TMEM25 or LSR molecules, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders.
    Type: Application
    Filed: May 18, 2021
    Publication date: February 17, 2022
    Inventors: Amir TOPORIK, Amit NOVIK, Ronen SHEMESH
  • Publication number: 20180194829
    Abstract: This invention relates to LY6G6F, VSIG10, TMEM25 and LSR proteins, which are suitable targets for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders, and drug development. This invention further relates to soluble LY6G6F, VSIG10, TMEM25 and LSR molecules, extracellular domains of LY6G6F, VSIG10, TMEM25 and LSR and conjugates, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders. This invention further relates to antibodies and antigen binding fragments and conjugates containing same, and/or alternative scaffolds, specific for LY6G6F, VSIG10, TMEM25 or LSR molecules, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders.
    Type: Application
    Filed: November 13, 2017
    Publication date: July 12, 2018
    Inventors: Amir TOPORIK, Amit NOVIK, Ronen SHEMESH
  • Publication number: 20160347816
    Abstract: This invention relates to LY6G6F, VSIG10, TMEM25 and LSR proteins, which are suitable targets for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders, and drug development. This invention further relates to soluble LY6G6F, VSIG10, TMEM25 and LSR molecules, extracellular domains of LY6G6F, VSIG10, TMEM25 and LSR and conjugates, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders. This invention further relates to antibodies and antigen binding fragments and conjugates containing same, and/or alternative scaffolds, specific for LY6G6F, VSIG10, TMEM25 or LSR molecules, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders.
    Type: Application
    Filed: February 29, 2016
    Publication date: December 1, 2016
    Inventors: Amir TOPORIK, Amit NOVIK, Ronen SHEMESH
  • Patent number: 9428586
    Abstract: The present invention, in at least some aspects, is of splice variants of heparanase, as well as diagnostic kits and methods of use, and therapeutic agents and methods of use based thereon, and antibodies specifically binding thereof.
    Type: Grant
    Filed: November 30, 2010
    Date of Patent: August 30, 2016
    Assignee: COMPUGEN LTD
    Inventors: Ronen Shemesh, Michal Ayalon-Soffer, Zurit Levine, Sergey Nemzer, Tomer Zekharya, Gad S. Cojocaru, Uri Barash, Neta Ilan, Israel Vlodavsky, Iris Hecht
  • Patent number: 9409987
    Abstract: This invention relates to LY6G6F, VSIG10, TMEM25 and LSR proteins, which are suitable targets for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders, and drug development. This invention further relates to soluble LY6G6F, VSIG10, TMEM25 and LSR molecules, extracellular domains of LY6G6F, VSIG10, TMEM25 and LSR and conjugates, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders. This invention further relates to antibodies and antigen binding fragments and conjugates containing same, and/or alternative scaffolds, specific for LY6G6F, VSIG10, TMEM25 or LSR molecules, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: August 9, 2016
    Assignee: COMPUGEN LTD
    Inventors: Amir Toporik, Amit Novik, Ronen Shemesh
  • Publication number: 20150307572
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Application
    Filed: February 23, 2015
    Publication date: October 29, 2015
    Inventors: Ronen Shemesh, Zurit Levine, Amir Toporik, Chen Hermesh, Yossef Kliger, Eyal Gofer, Assaf Wool, Dvir Dahary, Yossi Cohen
  • Patent number: 8987191
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: March 24, 2015
    Assignee: Compugen Ltd.
    Inventors: Ronen Shemesh, Zurit Levine, Amir Toporik, Chen Hermesh, Yossef Kliger, Eyal Gofer, Assaf Wool, Dvir Dahary, Yossi Cohen
  • Patent number: 8934592
    Abstract: A method is provided for synchronizing binary data transmitted in parallel via N channels. The method comprises performing at the receiver side, a data-clock-alignment for the data in the N channels by selecting an optimal reference channel to which no delay will be added, and adding an appropriate delay to each of the remaining channels, until their respective centers of valid data portions are aligned to each other, and associating clock edges with the centers of the valid data portions. The method is characterized in that the alignment is performed regardless to whether binary word alignment is simultaneously achieved or not, and wherein the optimal reference channel allows aligning the centers of valid data of all the channels while adding a minimal delay to a worst channel from among the remaining channels, wherein the worst channel carries valid data portions which are maximally shifted from those of the reference channel.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: January 13, 2015
    Assignee: ECI Telecom Ltd.
    Inventor: Ronen Shemesh
  • Publication number: 20150005227
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Application
    Filed: September 7, 2014
    Publication date: January 1, 2015
    Inventors: YOSSI COHEN, RONEN SHEMESH, AMIR TOPORIK, ZURIT LEVINE, ASSAF WOOL, DVIR DAHARY, IRIS HECHT, GALIT ROTMAN, MICHAL AYALON-SOFFER
  • Patent number: 8828940
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: September 9, 2014
    Assignee: Compugen Ltd.
    Inventors: Yossi Cohen, Ronen Shemesh, Amir Toporik, Zurit Levine, Assaf Wool, Dvir Dahary, Iris Hecht, Galit Rotman, Michal Ayalon-Soffer
  • Publication number: 20140056811
    Abstract: The present invention is related to peptides, which are suitable for use as cell-penetrating peptides (CPPs), variants thereof and/or complexes, fusion molecules and/or conjugates comprising same, use thereof for manufacture of compositions for diagnosing, treating and/or preventing of medical conditions.
    Type: Application
    Filed: December 26, 2011
    Publication date: February 27, 2014
    Applicant: COMPUGEN LTD.
    Inventors: Etai Jacob, Amir Toporik, Ronen Shemesh, Ofer Levy
  • Publication number: 20140044641
    Abstract: This invention relates to LY6G6F, VSIG10, TMEM25 and LSR proteins, which are suitable targets for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders, and drug development. This invention further relates to soluble LY6G6F, VSIG10, TMEM25 and LSR molecules, extracellular domains of LY6G6F, VSIG10, TMEM25 and LSR and conjugates, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders. This invention further relates to antibodies and antigen binding fragments and conjugates containing same, and/or alternative scaffolds, specific for LY6G6F, VSIG10, TMEM25 or LSR molecules, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders.
    Type: Application
    Filed: April 16, 2012
    Publication date: February 13, 2014
    Applicant: COMPUGEN LTD.
    Inventors: Amir Toporik, Amit Novik, Ronen Shemesh
  • Publication number: 20140005097
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Application
    Filed: June 21, 2013
    Publication date: January 2, 2014
    Applicant: Compugen Ltd.
    Inventors: Ronen Shemesh, Zurit Levine, Amir Toporik, Chen Hermesh, Yossef Kliger, Eyal Gofer, Assaf Wool, Dvir Dahary, Yossi Cohen
  • Patent number: 8492329
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Grant
    Filed: July 11, 2008
    Date of Patent: July 23, 2013
    Assignee: Compugen Ltd.
    Inventors: Ronen Shemesh, Zurit Levine, Amir Toporik, Chen Hermesh, Yossef Klinger, Eyal Gofer, Assaf Wool, Dvir Dahary, Yossi Cohen
  • Patent number: 8349801
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating myocardial and ischemic disorders associated with G-protein coupled receptor activation.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: January 8, 2013
    Assignee: Compugen Ltd.
    Inventors: Yossi Cohen, Ronen Shemesh, Amir Toporik, Zurit Levine, Assaf Wool, Dvir Dahary, Iris Hecht, Merav Beiman, Galit Rotman, Michal Ayalon-Soffer
  • Publication number: 20120301475
    Abstract: The present invention, in at least some aspects, is of splice variants of heparanase, as well as diagnostic kits and methods of use, and therapeutic agents and methods of use based thereon, and antibodies specifically binding thereof.
    Type: Application
    Filed: November 30, 2010
    Publication date: November 29, 2012
    Inventors: Ronen Shemesh, Michal Ayalon-Soffer, Zurit Levine, Sergey Nemzer, Tomer Zekharya, Gad S. Cojocaru, Uri Barash, Neta Ilan, Israel Vlodavsky, Iris Hecht
  • Publication number: 20120129776
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Application
    Filed: September 18, 2007
    Publication date: May 24, 2012
    Inventors: Yossi Cohen, Ronen Shemesh, Amir Toporik, Zurit Levine, Assaf Wool, Dvir Dahary, Iris Hecht, Merav Beiman, Galit Rotman, Michal Ayalon-Soffer
  • Publication number: 20110212051
    Abstract: Novel polypeptides and polynucleotides encoding same are provided. Also provided methods and pharmaceutical compositions which can be used to treat various disorders such as cancer, immunological-related, blood-related and skin-related disorders using the polypeptides and polynucleotides of the present invention. Also provided are methods and kits for diagnosing, determining predisposition and/or prognosis of various disorders using as diagnostic markers the novel polypeptides and polynucleotides of the present invention.
    Type: Application
    Filed: February 28, 2011
    Publication date: September 1, 2011
    Inventors: Michal Ayalon-Soffer, Zurit Levine, Osnat Sella-Tavor, Alex Diber, Ronen Shemesh, Amir Toporik, Galit Rotman, Sergey Nemzer, Avi Rosenberg, Dvir Dahary, Assaf Wool, Gad S. Cojocaru, Pinchas Akiva, Sarah Pollock, Kinneret Savitsky, Jeanne Bernstein
  • Publication number: 20110177998
    Abstract: Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
    Type: Application
    Filed: July 11, 2008
    Publication date: July 21, 2011
    Inventors: Ronen Shemesh, Zurit Levine, Amir Toporik, Chen Hermesh, Yossef Kliger, Eyal Gofer, Assaf Wool, Dvir Dahary, Yossi Cohen
  • Patent number: 7939634
    Abstract: Novel polypeptides and polynucleotides encoding same are provided. Also provided methods and pharmaceutical compositions which can be used to treat various disorders such as cancer, immunological-related, blood-related and skin-related disorders using the polypeptides and polynucleotides of the present invention. Also provided are methods and kits for diagnosing, determining predisposition and/or prognosis of various disorders using as diagnostic markers the novel polypeptides and polynucleotides of the present invention.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: May 10, 2011
    Assignee: Compugen Ltd.
    Inventors: Michal Ayalon-Soffer, Zurit Levine, Osnat Sella-Tavor, Alex Diber, Ronen Shemesh, Amir Toporik, Galit Rotman, Sergey Nemzer, Avi Rosenberg, Dvir Dahary, Assaf Wool, Gad S. Cojocaru, Pinchas Akiva, Sarah Pollock, Kinneret Savitsky, Jeanne Bernstein