Abstract: The present application provides a fractional domain noise reduction method for a power signal, including: S1: estimating an optimal fractional Fourier transform angle {circumflex over (?)}0 of an original signal x(t); S2: calculating fractional Fourier transform of the original signal under the optimal fractional Fourier transform angle to obtain X{circumflex over (?)}0 (u); S3: performing band-pass filtering in an optimal fractional Fourier transform domain to obtain X{circumflex over (?)}0 (u)H(u); S4: calculating fractional Fourier transform of X{circumflex over (?)}0 (u)H(u) at an angle of ?X{circumflex over (?)}0 and S5: judging whether {circumflex over (?)}0 is equal to ?/2, if yes, ending the noise reduction, and if no, eliminating a recovered signal component x(t)=x(t)?X{circumflex over (?)}0(u)H(u), and then repeating the steps S1 to S5 again until the estimated optimal FRFT rotation angle is equal to ?/2.

Abstract: Pharmaceutical compositions of the invention comprise functionalized N,N-dialkylamino phenyl ethers derivatives having a disease-modifying action in the treatment of diseases associated with lysosomal storage dysfunction that include Gaucher's disease, and any disease or condition involving lysosomal storage dysfunction.

Abstract: Provided herein, in some embodiments, are devices, systems and methods for high-throughput single-cell polyomics (e.g., genomic, epigenomic, proteomic and/or phenotypic profile) analyses.

Abstract: This disclosure demonstrates an approach that translates synthetic DNA codes to spatial codes registered in nanoliter microchambers for multiplexed measurement of nearly any type of molecular targets (e.g., miRNAs, mRNAs, intracellular and surface proteins) in single cells.

Abstract: The present invention provides systems and methods for single-cell RNA sequencing. Embodiments of the methods of the present invention include the steps of: aligning a microwell array on top of a dielectrophoresis (DEP) single-cell-trapping nanowell array; loading a plurality of cells into the nanowell; applying electricity to the nanowell array to trap a quanta of cells equal to a quanta of electrode pairs in at least one nanowell of the nanowell array; discontinuing electricity to the nanowell array in order to transfer the loaded cells from the nanowells to the microwells; loading a plurality of barcoded beads into the microwells so that a single bead occupies each cell-loaded microwell; capturing RNA from the cells and retrieving the RNA-loaded beads; and, sequencing the captured RNA.

Abstract: The present invention discloses a determination method for a preferred habitat of fish and a terminal device, wherein the method comprises: acquiring parameter information of a water environment in which target fish is located, and establishing a 3D water environment model by utilizing the parameter information of the water environment; determining an ecological function of the target fish and constructing a bio-simulation model on the 3D water environment model by combining the ecological function; acquiring a movement locus of the target fish in the bio-simulation model and determining potential habitats of the target fish according to the movement locus; and determining the preferred habitat of the target fish from the potential habitats by utilizing a preference learning model based on a density accumulation method.

Abstract: The present disclosure relates generally to systems and methods for screening sample preparation conditions and, more specifically, high throughput screening of tissue sample preparation conditions.

Abstract: The present invention discloses a determination method for a preferred habitat of fish and a terminal device, wherein the method comprises: acquiring parameter information of a water environment in which target fish is located, and establishing a 3D water environment model by utilizing the parameter information of the water environment; determining an ecological function of the target fish and constructing a bio-simulation model on the 3D water environment model by combining the ecological function; acquiring a movement locus of the target fish in the bio-simulation model and determining potential habitats of the target fish according to the movement locus; and determining the preferred habitat of the target fish from the potential habitats by utilizing a preference learning model based on a density accumulation method.

Abstract: The present invention provides a QFN packaging structure and QFN packaging method. By providing the insulating layer on the outer side of the leads of the QFN packaging structure, a short circuit between the leads and the electromagnetic shielding layer can be prevented. In addition, the grounding lead is exposed from the insulating layer, such that the electromagnetic shielding layer is grounded via the grounding lead, thereby realizing the electromagnetic shielding design of the QFN packaging structure.

Abstract: An optical device includes a range finding module. The range finding module includes a first light condenser unit, a light emitting unit and a light receiving unit. The first light condenser unit defines an optical axis and a hole disposed along the optical axis. The first light condenser unit, the light emitting unit and the light receiving unit are sequentially arranged along the optical axis. The light is emitted by the light emitting unit, passes through the hole, reaches an object, is reflected by the object, is converged by the first light condenser unit and is received by the light receiving unit to generate an electrical signal.

Abstract: Provided herein, in some embodiments, are compositions and methods for producing a molecular expression map of a biological sample using Deterministic Barcoding in Tissue for spatial omics sequencing (DBiT-seq).

Abstract: A presentation server establishes a network connection with a presentation device and a client device. The presentation server is able to receive frame data transmitted by the presentation device and pointer coordinates transmitted by the client device. Therefore, the presentation server is able to display a virtual pointer on the presentation frame according to the pointer coordinates, so that the participant can operate the pointing device of the client device to control the virtual pointer so as to participate effectively in the presentation and interact with the speaker.

Abstract: A new lattice structure design or discrimination method inspired by the crystalline structure of high-entropy alloy is described. A method for providing a high-entropy lattice (HEL) having a pseudo-random lattice structure comprises fabricating a locally distorted lattice structure and generating a high-entropy lattice (HEL) having a macroscopically ordered configuration from the locally distorted lattice structure. An article of manufacture comprising a high-entropy lattice (HEL) having a pseudo-random lattice structure, wherein the pseudo-random lattice structure is a macroscopically ordered lattice structure that includes locally distorted lattice structures, may be provided.

Abstract: A battery pack includes a battery set, a current detection circuit, a control unit, and a current adjustment circuit. The battery set is connected to an output terminal and the output terminal is configured to connect a load. The current detection circuit is configured to detect a discharge current of the battery set. The control unit is connected to the current detection circuit and configured to determine a type of the load based on the discharge current of the battery set and to output a control signal based on the type of the load. The current adjustment circuit is connected to the control unit and configured to adjust the discharge current in response to the control signal.

Abstract: The present invention relates to a system, device, and method for the high throughput multiplexed detection of a wide number of compounds. The invention comprises of a microwell array coupled to a capture agent array to form a plurality of interfaces between a microwell and a set of immobilized capture agents. The set of capture agents comprises a plurality of distinguishable features, with each feature corresponding to the detection of a particular compound of interest. In certain embodiments, each microwell is configured to contain a single cell. The invention is therefore capable of performing a high throughput analysis of single cell profiles, including profiles of secreted compounds.

Abstract: In a network (1) of communicatively interconnected (9) node devices (2-8), such as a Zigbee™ enabled mesh network, application data, such as data from or to sensors (12-17) operatively connected (17; 18) to the node devices (2-8), are periodically exchanged by attaching the application data to periodically exchanged operational messages that are to be transmitted by a node device (2-8) in the network (1), such as the link status command messages according to the Zigbee protocol.

Abstract: A method of forming a composite material includes: a) providing a substrate with fibres, lignin and hemicellulose; b) partially removing the lignin and hemicellulose from the substrate; and c) compressing the remaining substrate to form a compressed substrate. A composite material formed by the method is also provided.

Abstract: The present disclosure provides systems and methods for producing olefins via an oxidative coupling of methane (OCM) process. The systems and methods may comprise the use of a staged process comprising at least one non-adiabatic section that is in thermal communication with a heat transfer medium and at least one substantially adiabatic section. The systems and methods may also comprise the use of a diluent stream which may improve methane conversion in an OCM reactor and an ethylene/ethane ratio in a post-bed cracking unit. The methods and systems may further comprise injecting oxygen (O2) and a paraffin into a gas stream containing a radical transfer agent to provide a reaction mixture. The reaction mixture may be held in a vessel for a time period greater than an auto-ignition delay time (AIDT), such that the reaction mixture may ignite to liberate heat and convert to a product mixture comprising olefins.

Abstract: The present invention relates to a system, device, and method for the high throughput multiplexed detection of a wide number of compounds. The invention comprises of a microwell array coupled to a capture agent array to form a plurality of interfaces between a microwell and a set of immobilized capture agents. The set of capture agents comprises a plurality of distinguishable features, with each feature corresponding to the detection of a particular compound of interest. In certain embodiments, each microwell is configured to contain a single cell. The invention is therefore capable of performing a high throughput analysis of single cell profiles, including profiles of secreted compounds.