Patents by Inventor Rong-Tsun Wu

Rong-Tsun Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8420135
    Abstract: A method for treating immunological diseases and/or disorders associated with tumor necrosis factor-alpha (TNF-?) in a subject in need thereof is disclosed. The method comprises administering to a subject in need thereof a therapeutically effective amount of the coconut (Cocos nucifera Linn.) water extract or coconut (Cocos nucifera Linn.) shell extract through induction of transforming growth factor beta (TGF-?) or interleukin-10 (IL-10) as endogenous immunosuppressive factors.
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: April 16, 2013
    Inventor: Rong-Tsun Wu
  • Patent number: 8168236
    Abstract: Disclosed herein are processes for preparing extract products from the root of Polygonum multiflorum Thunb. and the extract products thus obtained, which are biologically active in promoting the proliferation, growth and/or differentiation of hematocytes and bone marrow cells in vitro and in vivo.
    Type: Grant
    Filed: December 31, 2007
    Date of Patent: May 1, 2012
    Assignee: National Yang-Ming University
    Inventor: Rong-Tsun Wu
  • Patent number: 8067039
    Abstract: An extract of plant Dendrobii Caulis and preparing process thereof are provided. A physiologically active extract of a plant Dendrobii Caulis and the method thereof are provided in the present invention. The extract is obtained by an extraction of the plant or parts thereof with a water miscible organic solvent or a mixture thereof with water.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: November 29, 2011
    Assignee: National Yang-Ming University
    Inventor: Rong-Tsun Wu
  • Publication number: 20110123648
    Abstract: A method for treating immunological diseases and/or disorders associated with tumor necrosis factor-alpha (TNF-?) in a subject in need thereof is disclosed. The method comprises administering to a subject in need thereof a therapeutically effective amount of the coconut (Cocos nucifera Linn.) water extract or coconut (Cocos nucifera Linn.) shell extract through induction of transforming growth factor beta (TGF-?) or interleukin-10 (IL-10) as endogenous immunosuppressive factors.
    Type: Application
    Filed: November 24, 2010
    Publication date: May 26, 2011
    Inventor: Rong-Tsun Wu
  • Patent number: 7939110
    Abstract: The present invention provides the composition and the method for treating autoimmune diseases and a mucosal disorder via oral-tolerance induction and innate immunity promotion. The composition for treating the autoimmune disease and mucosal disorder includes the polysaccharide prepared from a plant, wherein the plant belongs to Genus Dendrobium.
    Type: Grant
    Filed: September 5, 2007
    Date of Patent: May 10, 2011
    Assignee: National Yang-Ming University
    Inventor: Rong-Tsun Wu
  • Patent number: 7935684
    Abstract: The present invention relates to use of polysaccharides obtained from Dendrobium for treating an allergic disease or for reducing airway-remodeling caused by inflammation.
    Type: Grant
    Filed: July 22, 2008
    Date of Patent: May 3, 2011
    Assignee: National Yang-Ming University
    Inventor: Rong-Tsun Wu
  • Publication number: 20110003761
    Abstract: A substance having the following formula is provided. wherein R1 and R2 are selected from a group consisting of ?-Arabinose, ?-Arabinose and ?-Xylose. The substance has an effect of accelerating a phagocytosis of RPE.
    Type: Application
    Filed: March 1, 2010
    Publication date: January 6, 2011
    Inventor: Rong-Tsun WU
  • Publication number: 20100160243
    Abstract: Compounds and methods for enhancing erythropoiesis. The compound contains a chemical structure of the formula (I) indicated below, in which R is a glucosyl group. In addition to having an erythropoiesis effect, the compound of the formula (1) is effective in enhancing erythropoietin formation, and increasing kidney function and expression of hepatocyte growth factor. The method includes the step of administering an effective amount of the compound of the formula (I) to a subject in need thereof and thereby results in an enhancement of erythropoiesis.
    Type: Application
    Filed: December 24, 2008
    Publication date: June 24, 2010
    Applicant: National Yang-Ming University
    Inventor: Rong-Tsun WU
  • Publication number: 20100022470
    Abstract: The present invention relates to use of polysaccharides obtained from Dendrobium for treating an allergic disease or for reducing airway-remodeling caused by inflammation.
    Type: Application
    Filed: July 22, 2008
    Publication date: January 28, 2010
    Inventor: Rong-Tsun Wu
  • Patent number: 7645463
    Abstract: The present invention provides a method for treating diabetic vascular complications including administering to a subject in need thereof a therapeutically effective amount of an extract product of a Dioscorea species. The extract product preferably is prepared by a process which involves (a) extracting a tuber of the Dioscorea species with an alcohol-based solvent in the presence of an acetic acid solution to form an extract composition, (b) subjecting a resultant product obtained in step (a) to obtain a soluble fraction, and (c) removing solvent from the soluble fraction obtained in step (b) to obtain the extract product.
    Type: Grant
    Filed: October 18, 2006
    Date of Patent: January 12, 2010
    Assignee: National Yang-Ming University
    Inventor: Rong-Tsun Wu
  • Publication number: 20090258034
    Abstract: A method for inducing mucosal immune responses in a subject in need thereof to an antigen includes administering to the subject a vaccine composition including the antigen and a Dioscorea polysaccharides as an adjuvant. Because of the immuomodulatory effect of the Dioscorea polysaccharides, the vaccine composition is further capable of breaking immunological tolerance in the subject.
    Type: Application
    Filed: April 27, 2009
    Publication date: October 15, 2009
    Applicant: NATIONAL YANG-MING UNIVERSITY
    Inventor: Rong-Tsun WU
  • Publication number: 20090214681
    Abstract: A method for treating a disease or disorder associated with retinal pigment epithelium (RPE) disturbance, comprising administering to a human in need thereof an effective amount of a black soybean (Glycine max (L.) Merr) product is provided, wherein the black soybean product is the seed coats of black soybean or an alcoholic extract of black soybean or seed coats thereof.
    Type: Application
    Filed: February 25, 2008
    Publication date: August 27, 2009
    Inventor: Rong-Tsun Wu
  • Publication number: 20090208595
    Abstract: An extract of plant Dendrobii Caulis and preparing process thereof are provided. A physiologically active extract of a plant Dendrobii Caulis and the method thereof are provided in the present invention. The extract is obtained by an extraction of the plant or parts thereof with a water miscible organic solvent or a mixture thereof with water.
    Type: Application
    Filed: December 10, 2008
    Publication date: August 20, 2009
    Inventor: Rong-Tsun Wu
  • Publication number: 20090137631
    Abstract: Methods and pharmaceutical compositions for regulations of Guanosine- (G-) and/or Guanosine-cytosine-rich (GC-rich) nucleic acid expressions are provided. The methods include a step of interacting the G- and/or GC-rich region of the nucleic acid with thalidomide, and the pharmaceutical compositions include the thalidomide and a pharmaceutical carrier.
    Type: Application
    Filed: October 23, 2008
    Publication date: May 28, 2009
    Applicant: NATIONAL YANG-MING UNIVERSITY
    Inventor: Rong-Tsun Wu
  • Publication number: 20090136600
    Abstract: Extract fractions of Dioscorea sp. and methods of preparing the extract fractions are disclosed. The extract fractions enhance the proliferation and differentiation of bone marrow cells. Also described are a method for treatment of osteoporosis and a method for alleviation of side effects caused by chemotherapy by using the extract fractions of Dioscorea sp.
    Type: Application
    Filed: December 3, 2008
    Publication date: May 28, 2009
    Applicant: NATIONAL YANG MING UNIVERSITY
    Inventor: Rong-Tsun WU
  • Publication number: 20090099128
    Abstract: The present invention provides the composition and the method for treating autoimmune diseases and a mucosal disorder via oral-tolerance induction and innate immunity promotion. The composition for treating the autoimmune disease and mucosal disorder includes the polysaccharide prepared from a plant, wherein the plant belongs to Genus Dendrobium.
    Type: Application
    Filed: September 5, 2007
    Publication date: April 16, 2009
    Applicant: National Yang-Ming University
    Inventor: Rong-Tsun Wu
  • Publication number: 20090098229
    Abstract: A method for treating osteoporosis in a subject in need of such treatment includes administering orally to the subject an effective amount of an extract product of a Dioscorea species capable of promoting proliferation and differentiation of bone marrow cells in the subject. Particularly, the Dioscorea species is Dioscorea alata L. cv.
    Type: Application
    Filed: November 26, 2008
    Publication date: April 16, 2009
    Applicant: NATIONAL YANG MING UNIVERSITY
    Inventor: RONG-TSUN WU
  • Publication number: 20090092697
    Abstract: Disclosed herein are processes for preparing extract products from the root of Polygonum multiflorum Thunb. and the extract products thus obtained, which are biologically active in promoting the proliferation, growth and/or differentiation of hematocytes and bone marrow cells in vitro and in vivo.
    Type: Application
    Filed: December 31, 2007
    Publication date: April 9, 2009
    Applicant: National Yang-Ming University
    Inventor: Rong-Tsun Wu
  • Publication number: 20090074896
    Abstract: Disclosed herein are processes for preparing extract products from the root of Polygonum multiflorum Thunb. and the extract products thus obtained, which are biologically active in promoting the proliferation, growth and/or differentiation of hematocytes and bone marrow cells in vitro and in vivo.
    Type: Application
    Filed: August 15, 2007
    Publication date: March 19, 2009
    Applicant: National Yang-Ming University
    Inventor: Rong-Tsun Wu
  • Publication number: 20090005324
    Abstract: A substance having the following formula is provided. wherein R1 and R2 are selected from a group consisting of ?-Ara, ?-Ara and ?-Xyl. The substance has an effect of accelerating a phagocytosis of RPE.
    Type: Application
    Filed: June 29, 2007
    Publication date: January 1, 2009
    Inventor: Rong-Tsun Wu