Patents by Inventor Rongxian Shen

Rongxian Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-HIV vaccine constructed based on amino acid mutations in attenuated live EIAV vaccine
    Patent number: 10251948
    Abstract: Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: April 9, 2019
    Assignee: National Center for AIDS/STD Control And Prevention, Chinese Center for Disease Control and Prevention
    Inventors: Yiming Shao, Lianxing Liu, Rongxian Shen
  • Anti-HIV Vaccine Constructed Based on Amino Acid Mutations in Attenuated Live EIAV Vaccine
    Publication number: 20150132332
    Abstract: Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
    Type: Application
    Filed: January 21, 2015
    Publication date: May 14, 2015
    Inventors: YIMING SHAO, LIANXING LIU, RONGXIAN SHEN
  • Anti-HIV vaccine constructed based on amino acid mutations in attenuated live EIAV vaccine
    Patent number: 8956620
    Abstract: Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: February 17, 2015
    Assignee: National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention
    Inventors: Yiming Shao, Lianxing Liu, Rongxian Shen
  • Anti-HIV Vaccine Constructed Based on Amino Acid Mutations in Attenuated Live EIAV Vaccine
    Publication number: 20110195084
    Abstract: Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
    Type: Application
    Filed: May 27, 2009
    Publication date: August 11, 2011
    Applicant: National Center for AIDS/STD Control and Preventio Chinese Center for Disease Control and Prevention
    Inventors: Yiming Shao, Lianxing Liu, Rongxian Shen
  • Full-gene sequence of the donkey leukocyte vaccine strain of the equine infectious anemia virus and their application
    Patent number: 6987020
    Abstract: This invention discloses the full-length proviral genome DNA sequence of Donkey Leukocyte Attenuated Equine Infectious Anemia Virus Vaccine strain, nucleotide and amino acid sequences of all functional genes, and uses of each functional gene and its expression product. The vaccine strain involved in this invention was derived from an isolate in China.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: January 17, 2006
    Assignees: National Center for Aids Prevention and Control, Harbin Veterinary Research Institute, Chinese Academy of Agriculture Science
    Inventors: Yiming Shao, Rongxian Shen, Gang Chen, Kangzhen Yu, Pinliang Pan, Bin Jia, Yi Feng, Fel Xue, Wenhua Xiang, Xiujuan Fan, Xieoling Lu, Liping Zhao