Patents by Inventor Roshan Thapa

Roshan Thapa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA VIRUS VECTORS CARRYING DAI AND RIPK3
    Publication number: 20220348959
    Abstract: RNA virus vectors comprising a gene encoding the DNA-dependent activator of interferon-regulatory factors (DAI) protein, and optionally further comprising a gene encoding the receptor-interacting serine; threonine-protein kinase 3 (RIPK3) may be used therapeutically to induce cell death, as well as an inflammatory immune response, against tumors and virally-infected cells.
    Type: Application
    Filed: April 18, 2022
    Publication date: November 3, 2022
    Inventors: Siddharth Balachandran, Roshan Thapa
  • RNA virus vectors carrying DAI and RIPK3
    Patent number: 11332756
    Abstract: RNA virus vectors comprising a gene encoding the DNA-dependent activator of interferon-regulatory factors (DAI) protein, and optionally further comprising a gene encoding the receptor-interacting serine/threonine-protein kinase 3 (RIPK3) may be used therapeutically to induce cell death, as well as an inflammatory immune response, against tumors and virally-infected cells.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: May 17, 2022
    Assignee: Institute For Cancer Research
    Inventors: Siddharth Balachandran, Roshan Thapa
  • RNA VIRUS VECTORS CARRYING DAI AND RIPK3
    Publication number: 20190211359
    Abstract: RNA virus vectors comprising a gene encoding the DNA-dependent activator of interferon-regulatory factors (DAI) protein, and optionally further comprising a gene encoding the receptor-interacting serine/threonine-protein kinase 3 (RIPK3) may be used therapeutically to induce cell death, as well as an inflammatory immune response, against tumors and virally-infected cells.
    Type: Application
    Filed: July 5, 2017
    Publication date: July 11, 2019
    Applicant: Institute For Cancer Research d/b/a The Research Institute Of Fox Chase Cancer Center
    Inventors: Siddharth Balachandran, Roshan Thapa