Patents by Inventor Ross M. Kedl

Ross M. Kedl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOSTIMULATORY COMBINATIONS
    Publication number: 20190083592
    Abstract: The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
    Type: Application
    Filed: October 22, 2018
    Publication date: March 21, 2019
    Inventors: Randolph J. NOELLE, Cory L. AHONEN, Ross M. KEDL
  • Immunostimulatory combinations
    Patent number: 10105426
    Abstract: The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: October 23, 2018
    Assignee: TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Randolph J. Noelle, Cory L. Ahonen, Ross M. Kedl
  • METHODS AND COMPOSITIONS FOR ENHANCING IMMUNE RESPONSE
    Publication number: 20170319712
    Abstract: Methods and compositions for enhancing the immune response to an IRM compound by depositing within a localized tissue region an IRM depot preparation that provides an extended residence time of active IRM within the localized tissue region.
    Type: Application
    Filed: July 27, 2017
    Publication date: November 9, 2017
    Applicant: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: RICHARD L. MILLER, MARK A. TOMAI, ROSS M. KEDL, ISIDRO ANGELO ELEAZAR ZARRAGA, RONNIE ORTIZ, JAMES D. STOESZ, PAUL D. WIGHTMAN
  • Methods and compositions for enhancing immune response
    Patent number: 9801947
    Abstract: Methods and compositions for enhancing the immune response to an IRM compound by depositing within a localized tissue region an IRM depot preparation that provides an extended residence time of active IRM within the localized tissue region.
    Type: Grant
    Filed: October 6, 2014
    Date of Patent: October 31, 2017
    Assignee: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Richard L. Miller, Mark A. Tomai, Ross M. Kedl, Isidro Angelo Eleazar Zarraga, Ronnie Ortiz, James D. Stoesz, Paul D. Wightman
  • Immunostimulatory Combinations
    Publication number: 20160129095
    Abstract: The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
    Type: Application
    Filed: September 10, 2015
    Publication date: May 12, 2016
    Inventors: Randolph J. NOELLE, Cory L. Ahonen, Ross M. Kedl
  • Immunotherapy comprising TLR9 ligand and CD40 ligand
    Patent number: 9161976
    Abstract: The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
    Type: Grant
    Filed: October 22, 2012
    Date of Patent: October 20, 2015
    Assignee: Trustees of Dartmouth College
    Inventors: Randolph J. Noelle, Cory L. Ahonen, Ross M. Kedl
  • Delivery of immune response modifier compounds
    Patent number: 8961477
    Abstract: Delivery of one or more immune response modifiers (IRMs) across a biological barrier by the use of a microneedle device.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: February 24, 2015
    Assignee: 3M Innovative Properties Company
    Inventors: James T. Wolter, Ross M. Kedl
  • METHODS AND COMPOSITIONS FOR ENHANCING IMMUNE RESPONSE
    Publication number: 20150044279
    Abstract: Methods and compositions for enhancing the immune response to an IRM compound by depositing within a localized tissue region an IRM depot preparation that provides an extended residence time of active IRM within the localized tissue region.
    Type: Application
    Filed: October 6, 2014
    Publication date: February 12, 2015
    Inventors: Richard L. Miller, Mark A. Tomai, Ross M. Kedl, Isidro Angelo Eleazar Zarraga, Ronnie Ortiz, James D. Stoesz, Paul D. Wightman
  • USE OF TLR AGONISTS AND/OR TYPE 1 INTERFERONS TO ALLEVIATE TOXICITY OF TNF-R AGONIST THERAPEUTIC REGIMENS
    Publication number: 20130302278
    Abstract: Improved (safer and more effective) methods of therapy using TNF-R agonists, e.g., CD40 agonists are provided. These methods provide for the addition of an amount of a type 1 interferon and/or a TLR agonist that is effective to prevent or reduce the toxicity (liver toxicity) that may otherwise result in some patients of the TNF-R agonist is used as a monotherapy (without the type 1 interferon and/or TLR agonist).
    Type: Application
    Filed: April 16, 2013
    Publication date: November 14, 2013
    Inventors: Randolph J. Noelle, Ross M. Kedl, Cory L. Ahonen
  • Ex vivo uses of immunostimulatory combinations
    Patent number: 8329197
    Abstract: The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
    Type: Grant
    Filed: July 29, 2010
    Date of Patent: December 11, 2012
    Assignees: 3M Innovative Properties Company, Trustees of Dartmouth
    Inventors: Randolph J. Noelle, Cory L. Ahonen, Ross M. Kedl
  • TLR9 agonist and CD40 agonist immunostimulatory combinations
    Patent number: 7993659
    Abstract: The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: August 9, 2011
    Assignees: 3M Innovative Properties Company, Trustees of Dartmouth College
    Inventors: Randolph J. Noelle, Cory L. Ahonen, Ross M. Kedl
  • IMMUNOSTIMULATORY COMBINATIONS
    Publication number: 20090123460
    Abstract: The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
    Type: Application
    Filed: March 17, 2008
    Publication date: May 14, 2009
    Applicant: 3M Innovative Properties Company
    Inventors: Randolph J. NOELLE, Cory L. Ahonen, Ross M. Kedl
  • Immunostimulatory compositions and methods of stimulating an immune response
    Patent number: 7427629
    Abstract: The present invention provides immunostimulatory compositions that include an immune response modifier portion paired with an antigenic portion.
    Type: Grant
    Filed: August 14, 2003
    Date of Patent: September 23, 2008
    Assignee: 3M Innovative Properties Company
    Inventors: Ross M. Kedl, George W. Griesgraber, Isidro Angelo E. Zarraga, Paul D. Wightman
  • Immunostimulatory combinations
    Patent number: 7387271
    Abstract: The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
    Type: Grant
    Filed: December 30, 2003
    Date of Patent: June 17, 2008
    Assignees: 3M Innovative Properties Company, Trustees of Dartmouth College
    Inventors: Randolph J. Noelle, Cory L. Ahonen, Ross M. Kedl
  • Methods and compositions for enhancing immune response
    Publication number: 20040265351
    Abstract: Methods and compositions for enhancing the immune response to an IRM compound by depositing within a localized tissue region an IRM depot preparation that provides an extended residence time of active IRM within the localized tissue region.
    Type: Application
    Filed: April 9, 2004
    Publication date: December 30, 2004
    Inventors: Richard L. Miller, Mark A. Tomai, Ross M. Kedl, Isidro Angelo Eleazar Zarraga, Ronnie Ortiz, James D. Stoesz
  • Immunostimulatory combinations
    Publication number: 20040141950
    Abstract: The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
    Type: Application
    Filed: December 30, 2003
    Publication date: July 22, 2004
    Applicant: 3M Innovative Properties Company
    Inventors: Randolph J. Noelle, Cory L. Ahonen, Ross M. Kedl
  • Immunostimulatory compositions and methods of stimulating an immune response
    Publication number: 20040091491
    Abstract: The present invention provides immunostimulatory compositions that include an immune response modifier portion paired with an antigenic portion.
    Type: Application
    Filed: August 14, 2003
    Publication date: May 13, 2004
    Applicant: 3M Innovative Properties Company
    Inventors: Ross M. Kedl, George W. Griesgraber, Isidro Angelo E. Zarraga
  • Electrospray coating apparatus and process utilizing precise control of filament and mist generation
    Patent number: 5326598
    Abstract: An electrospray coating head system for applying thin coating to a substrate comprising a slot or blade to meter a liquid onto a shaping structure which forces the liquid to have a single continuous and substantially constant radius of curvature around the shaping structure. A voltage applied to the liquid around the shaping structure causes the liquid to produce a series of filaments which are spatially and temporally fixed, the number of filaments being defined by a simple adjustment in the applied voltage. The filaments break up into a uniform mist of charge droplets and are driven to a substrate by electric fields to produce a coating.
    Type: Grant
    Filed: October 2, 1992
    Date of Patent: July 5, 1994
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Albert E. Seaver, William R. Berggren, Daniel R. Danielson, Eugene E. Harkins, Ross M. Kedl