Patents by Inventor Roxanne Croze

Roxanne Croze has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADENO-ASSOCIATED VARIANTS, FORMULATIONS AND METHODS FOR PULMONARY DELIVERY
    Publication number: 20240067987
    Abstract: The present disclosure provides a variant AAV capsid protein that confers tropism to lung cells and recombinant adeno-associated viruses comprising the variant A.AV and pharmaceutical compositions comprising same and their use in the delivery of heterologous nucleic acids to lung cells for the treatment of pulmonary disorders.
    Type: Application
    Filed: September 15, 2023
    Publication date: February 29, 2024
    Applicant: 4D MOLECULAR THERAPEUTICS INC.
    Inventors: Melissa Kotterman, Peter Francis, Melissa Calton, Johnny Gonzales, Roxanne Croze, Christopher Schmitt
  • Adeno-associated variants, formulations and methods for pulmonary delivery
    Patent number: 11807868
    Abstract: The present disclosure provides a variant AAV capsid protein that confers tropism to lung cells and recombinant adeno-associated viruses comprising the variant AAV and pharmaceutical compositions comprising same and their use in the delivery of heterologous nucleic acids to lung cells for the treatment of pulmonary disorders.
    Type: Grant
    Filed: October 6, 2022
    Date of Patent: November 7, 2023
    Assignee: 4D Molecular Therapeutics Inc.
    Inventors: Melissa Kotterman, Peter Francis, Melissa Calton, Johnny Gonzales, Roxanne Croze, Christopher Schmitt
  • ADENO-ASSOCIATED VARIANTS, FORMULATIONS AND METHODS FOR PULMONARY DELIVERY
    Publication number: 20230257772
    Abstract: The present disclosure provides a variant AAV capsid protein that confers tropism to lung cells and recombinant adeno-associated viruses comprising the variant AAV and pharmaceutical compositions comprising same and their use in the delivery of heterologous nucleic acids to lung cells for the treatment of pulmonary disorders.
    Type: Application
    Filed: October 6, 2022
    Publication date: August 17, 2023
    Applicant: 4D Molecular Therapeutics Inc.
    Inventors: Melissa Kotterman, Peter Francis, Melissa Calton, Johnny Gonzales, Roxanne Croze, Christopher Schmitt
  • Adeno-associated variants, formulations and methods for pulmonary delivery
    Patent number: 11499166
    Abstract: The present disclosure provides a variant AAV capsid protein that confers tropism to lung cells and recombinant adeno-associated viruses comprising the variant AAV and pharmaceutical compositions comprising same and their use in the delivery of heterologous nucleic acids to lung cells for the treatment of pulmonary disorders.
    Type: Grant
    Filed: April 26, 2021
    Date of Patent: November 15, 2022
    Assignee: 4D Molecular Therapeutics Inc.
    Inventors: Melissa Kotterman, Peter Francis, Melissa Calton, Johnny Gonzales, Roxanne Croze, Christopher Schmitt
  • ADENO-ASSOCIATED VARIANTS, FORMULATIONS AND METHODS FOR PULMONARY DELIVERY
    Publication number: 20210395772
    Abstract: The present disclosure provides a variant AAV capsid protein that confers tropism to lung cells and recombinant adeno-associated viruses comprising the variant AAV and pharmaceutical compositions comprising same and their use in the delivery of heterologous nucleic acids to lung cells for the treatment of pulmonary disorders.
    Type: Application
    Filed: April 26, 2021
    Publication date: December 23, 2021
    Applicant: 4D MOLECULAR THERAPEUTICS INC.
    Inventors: Melissa KOTTERMAN, Peter FRANCIS, Melissa CALTON, Johnny GONZALES, Roxanne CROZE, Christopher SCHMITT
  • Methods and compositions for the rapid production of retinal pigmented epithelial cells from pluripotent cells
    Patent number: 9458428
    Abstract: The invention relates to the field of cell culture, specifically, the derivation of retinal pigmented epithelial cells from pluripotent cells. The invention comprises the use of various cell culture medium supplements, medium formulations, and methods of using such medium supplements and formulations, in order to effect the rapid differentiation of pluripotent cells into retinal pigmented epithelial cells with very high yields. The invention further includes cell culture media formulations for the efficient maintenance, propagation, and maturation of cultured retinal pigmented epithelial cells.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: October 4, 2016
    Assignee: The Regents of the University of California
    Inventors: Dennis Clegg, David Buchholz, Roxanne Croze, Britney Pennington, Peter Coffey, Lyndsay Leach
  • Methods and Compositions for the Rapid Production of Retinal Pigmented Epithelial Cells from Pluripotent Cells
    Publication number: 20150175964
    Abstract: The invention relates to the field of cell culture, specifically, the derivation of retinal pigmented epithelial cells from pluripotent cells. The invention comprises the use of various cell culture medium supplements, medium formulations, and methods of using such medium supplements and formulations, in order to effect the rapid differentiation of pluripotent cells into retinal pigmented epithelial cells with very high yields. The invention further includes cell culture media formulations for the efficient maintenance, propagation, and maturation of cultured retinal pigmented epithelial cells.
    Type: Application
    Filed: June 5, 2013
    Publication date: June 25, 2015
    Inventors: Dennis Clegg, David Buchholz, Roxanne Croze, Britney Pennington, Peter Coffey, Lyndsay Leach