Patents by Inventor Roy Clinton Ogle

Roy Clinton Ogle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for making and using laminin nanofibers
    Patent number: 8728817
    Abstract: The present invention provides methodologies and parameters for fabrication of the hybrid biomaterial by blending pure laminin or complex extracts of tissues containing laminin with biopolymers such as polycaprolactone (PCL), polylactic/polyglycolic acid copolymer (PLGA) or Polydioxanone (PDO) in fluoroalcohols (HFP, TFA), fabrication of substrates and scaffolds and devices from the hybrid biomaterial in forms such as films, nanofibers by electrospinning or microspheres, and the biological or biomedical use of the material or devices derived from it.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: May 20, 2014
    Assignee: University of Virginia Patent Foundation
    Inventors: Roy Clinton Ogle, Edward A. Botchwey, III, Rebekah A. Neal
  • COMPOSITIONS AND METHODS FOR MAKING AND USING LAMININ NANOFIBERS
    Publication number: 20110236974
    Abstract: The present invention provides methodologies and parameters for fabrication of the hybrid biomaterial by blending pure laminin or complex extracts of tissues containing laminin with biopolymers such as polycaprolactone (PCL), polylactic/polyglycolic acid copolymer (PLGA) or Polydioxanone (PDO) in fluoroalcohols (HFP, TFA), fabrication of substrates and scaffolds and devices from the hybrid biomaterial in forms such as films, nanofibers by electrospinning or microspheres, and the biological or biomedical use of the material or devices derived from it.
    Type: Application
    Filed: March 10, 2011
    Publication date: September 29, 2011
    Applicant: University of Virginia Patent Foundation
    Inventors: Roy Clinton Ogle, Edward A. Botchwey, III, Rebekah A. Neal
  • Compositions and Methods for Making and Using Laminin Nanofibers
    Publication number: 20100120115
    Abstract: The present invention encompasses methodologies and parameters for the formation of nanofibrous (to microfibrous) laminin via electrospinning. The present application discloses conditions and appropriate parameters to synthesize laminin fibers from a diameter of about 10 nM to a diameter of over 1,000 nM via electrospinning.
    Type: Application
    Filed: May 2, 2008
    Publication date: May 13, 2010
    Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Roy Clinton Ogle, Edward A. Botchwey, III
  • Production of Osteoclasts from Adipose Tissues
    Publication number: 20080187518
    Abstract: The present invention provides methods for growing and inducing osteoclastic differentiation of adipose tissue derived cells. The present invention further provides methods for administering such adipose tissue derived cells to a subject. The present invention further provides methods for treating diseases, disorders, and conditions associated with aberrant regulation or numbers of osteoclasts.
    Type: Application
    Filed: May 25, 2006
    Publication date: August 7, 2008
    Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Roy Clinton Ogle, Ashok Tholpady, Sunil Shantigodu Tholpady