Patents by Inventor Roy D. Archibald

Roy D. Archibald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ophthalmic suspensions
    Patent number: 5192535
    Abstract: Lightly crosslinked polymers, preferably ones prepared by suspension or emulsion polymerizing at least about 90% by weight of a carboxyl-containing monoethylenically unsaturated monomer such as acrylic acid with from about 0.1% to about 5% by weight of a polyfunctional, and preferably difunctional, crosslinking agent such as divinyl glycol (3,4-dihydroxy-1,5-hexadiene), having a particle size of not more than about 50 .mu.m in equivalent spherical diameter, when formulated with an ophthalmic medicament, e.g., fluorometholone, into suspensions in aqueous medium in which the amount of polymer ranges from about 0.1% to about 6.5% by weight, based on the total weight of the aqueous suspension, the pH is from about 3.0 to about 6.
    Type: Grant
    Filed: June 27, 1990
    Date of Patent: March 9, 1993
    Assignee: InSite Vision Incorporated
    Inventors: Jeffrey P. Davis, Santosh K. Chandrasekaran, Yansheng Su, Roy D. Archibald, Joseph R. Robinson
  • Topical ophthalmic suspensions
    Patent number: 5188826
    Abstract: A topical, aqueous ophthalmic gel suspension for dry eye is administrable to the eye in drop form, remains as a gel in the eye for a prolonged time, and releases water and one or more ophthalmic demulcents or vasoconstrictors. It comprises water and from 0.1% to 6.5% by weight of lightly cross-linked carboxyl-containing polymer having a particle size of not more than about 50 .mu.m in equivalent spherical diameter. The suspension is at a pH of from 6.6 to 8.0, has an osmolality of from 50 to 400 mOsM, and a viscosity of from about 500 to about 4,000 centipoise (0.5 to 4 Pa.s).
    Type: Grant
    Filed: July 6, 1990
    Date of Patent: February 23, 1993
    Assignee: InSite Vision Incorporated
    Inventors: Santosh K. Chandrasekaran, Margaret J. Reents, John C. Babcock, Lyle M. Bowman, Roy D. Archibald, Joseph R. Robinson
  • Liquid droplet dispensing apparatus
    Patent number: 5040706
    Abstract: A disposable unit- or multi-dose liquid dispensing container device, particularly adapted for delivery of ophthalmic liquid medicament in the form of discrete droplets to the eye. The structural configuration of the device including an angularly offset leading end permits the user to employ a free hand for manipulation of the eyelid to enhance reception of the discharge opening of the dispenser into the conjunctival cul-de-sac while at the same time, enabling the user to look directly into a wall-mounted mirror for accurate placement of the medicament. A small capacity reservoir and ease of control of accurate orifice size enables the application of uniform liquid-ejection pressure by the user to deliver droplets of reproducible dosage size with the multi-dose embodiment.
    Type: Grant
    Filed: March 17, 1989
    Date of Patent: August 20, 1991
    Assignee: InSite Vision, Inc.
    Inventors: Jeffrey P. Davis, Roy D. Archibald, Christa D. Nicholas, Santosh K. Chandrasekaran
  • Thixotropic topical fluoride-phosphate gel compositions useful for the prevention of dental caries
    Patent number: 4267167
    Abstract: A thixotropic acidulated phosphate fluoride composition for the control and prevention of dental caries is disclosed.
    Type: Grant
    Filed: May 27, 1980
    Date of Patent: May 12, 1981
    Assignee: Cooper Care, Inc.
    Inventors: Stewart Weitzman, Roy D. Archibald