Patents by Inventor Roy K. Greenberg
Roy K. Greenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8945205Abstract: The present embodiments provide a branch vessel prosthesis for placement at least partially between a main vessel and a branch vessel of a patient. The branch vessel prosthesis has a graft including a generally tubular body of a biocompatible material. At least one stent is coupled to a proximal region of the graft, and at least one stent is coupled to a distal region of the graft. The proximal region of the graft includes a generally straight configuration in an expanded deployed state that is substantially parallel to a longitudinal axis of a main vessel. The distal region of the graft includes a generally straight configuration in the expanded deployed state that is substantially parallel to a branch vessel. A curvature of a central region varies an angle in which the distal region of the graft is disposed relative to the proximal region.Type: GrantFiled: April 18, 2012Date of Patent: February 3, 2015Assignee: The Cleveland Clinic FoundationInventor: Roy K. Greenberg
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Patent number: 8915955Abstract: A small vessel stent graft with a fixation coupling that has a hyperboloid shape positioned at or near the proximal end of the graft. The coupling may be deployed within the fenestration of a fenestrated graft to provide multi-directional movement without compromising the integrity of the sealing zone.Type: GrantFiled: August 24, 2009Date of Patent: December 23, 2014Assignee: The Cleveland Clinic FoundationInventors: Karl J. West, Roy K. Greenberg
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Patent number: 8911488Abstract: A stent graft delivery device (30) has a pull wire arrangement with a pull wire (46) fastened to the distal end of a nose cone dilator (45) and extending to a wire pull mechanism (60) for the pull wire associated with a handle (52) of the stent graft delivery device. The pull wire can be pulled by the wire pull mechanism to induce a curve in a guide wire catheter (44) distally of the nose cone dilator such that the proximal end of the delivery device more closely fits the shape of a portion of the vasculature of a patient into which the device is deployed.Type: GrantFiled: August 24, 2009Date of Patent: December 16, 2014Assignees: The Cleveland Clinic Foundation, Cook Medical Technologies LLCInventors: David E. Hartley, Timothy A. Chuter, Roy K. Greenberg
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Publication number: 20140364932Abstract: An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (22) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.Type: ApplicationFiled: August 26, 2014Publication date: December 11, 2014Inventors: David Ernest Hartley, John Lennon Anderson, Roy K. Greenberg, Wolf Stelter
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Publication number: 20140364931Abstract: An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (22) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.Type: ApplicationFiled: August 26, 2014Publication date: December 11, 2014Inventors: David Ernest Hartley, John Lennon Anderson, Roy K. Greenberg, Wolf Stelter
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Publication number: 20140364933Abstract: An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (22) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.Type: ApplicationFiled: August 26, 2014Publication date: December 11, 2014Inventors: David Ernest Hartley, John Lennon Anderson, Roy K. Greenberg, Wolf Stelter
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Publication number: 20140364934Abstract: An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (22) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.Type: ApplicationFiled: August 26, 2014Publication date: December 11, 2014Inventors: David Ernest Hartley, John Lennon Anderson, Roy K. Greenberg, Wolf Stelter
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Patent number: 8864808Abstract: A stent graft delivery system in which a stent graft (6) is retained on a delivery device (2) such that a longitudinal portion of the stent graft is releasably retained on the delivery device to bend therewith. The delivery device (2) has a guide wire catheter (3) and the stent graft is retained onto the guide wire catheter by a release wire (24) which can be withdrawn. The release wire is wound around the guide wire catheter and through the stent graft or suture loops engage around the guide wire catheter and release wire.Type: GrantFiled: September 21, 2006Date of Patent: October 21, 2014Assignees: The Cleveland Clinic Foundation, Cook Medical Technologies LLCInventors: Roy K. Greenberg, David Ernest Hartley
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Patent number: 8845708Abstract: A stent graft introducer has a pusher, a nose cone, a region between the pusher and the nose cone for a stent graft, a sleeve extending over the pusher and proximally to the nose cone to cover the stent graft when retained in the region. An indwelling auxiliary catheter with a pre-curved proximal end is fitted into the introducer. The nose cone has an elongate groove and the auxiliary catheter has its proximal end in the elongate groove. In a partially retracted position of the sleeve the curved proximal end of the indwelling auxiliary catheter is exposed and uncovered by the sleeve and in an advanced position of the sleeve the curved proximal end of the indwelling auxiliary catheter is straightened, extends along the length of the groove in the nose cone and is covered by the sleeve.Type: GrantFiled: November 16, 2006Date of Patent: September 30, 2014Assignees: The Cleveland Clinic Foundation, Cook Medical Technologies LLCInventors: David Ernest Hartley, Krasnodar Ivancev, Roy K. Greenberg
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Publication number: 20140236277Abstract: A pre-loaded stent graft delivery device and stent graft, the stent graft delivery device. The stent graft has at least one fenestration or side arm and the fenestration is preloaded with an indwelling guide wire. Indwelling access sheaths are provided within auxiliary lumens of a pusher catheter and dilators are preloaded into the access sheaths along with the indwelling guide wire. A handle assembly at a distal end of the guide wire catheter. The handle includes a multiport manifold with access ports to the auxiliary lumens in the pusher catheter. Upon deployment of the stent graft into the vasculature of a patient, the indwelling guide wire can be used to facilitate cathertisation of a side branch or target vessel through the fenestration or be used to stabilise the access sheath during catheterisation, advancement of the access sheath into the target vessel and deployment of a covered or uncovered stent therein through the access sheath.Type: ApplicationFiled: April 28, 2014Publication date: August 21, 2014Applicant: Cook Medical Technologies LLCInventors: Roy K. Greenberg, Krasnodar Ivancev, David Ernest Hartley, Werner D. Ducke, Erik Rasmussen
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Patent number: 8788065Abstract: A method is provided for renal neuromodulation. One step of the method includes providing an expandable support member having a cuff-like configuration and including a main body portion (MBP). The MBP includes a lumen for engaging a wall of a blood vessel including a portion of a renal vasculature. At least one electrode connected with the MBP is arranged to selectively deliver electric current to a desired location. An insulative material is attached to at least a portion of the MBP. Next, the MBP is implanted extravascularly so that the MBP is in direct contact with a portion of the renal vasculature. At least one electrode is positioned substantially adjacent a desired location where modulation of the sympathetic nervous system (SNS) is effective to alter renal function. Electric current is then delivered to the at least one electrode to effect a change in the SNS.Type: GrantFiled: February 22, 2012Date of Patent: July 22, 2014Assignee: The Cleveland Clinic FoundationInventors: Ali R. Rezai, Roy K. Greenberg, Milind Deogaonkar
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Publication number: 20140180394Abstract: The present embodiments provide an endoluminal prosthesis having modular branches, and systems and methods for facilitating deployment of the endoluminal prosthesis. In one example, the endoluminal prosthesis comprises a graft including a bifurcated body of a biocompatible material. The bifurcated body includes distally extending limbs. Limb extensions can be longitudinally and circumferentially adjusted prior to mating with the limbs to enable an “off-the-shelf” prosthesis that can conform to various complex anatomy. When adjusted and mated, fenestrations in the limb extensions can align with branch vessels.Type: ApplicationFiled: December 23, 2013Publication date: June 26, 2014Applicant: COOK MEDICAL TECHNOLOGIES LLCInventors: Roy K. Greenberg, Blayne A. Roeder
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Patent number: 8758425Abstract: A stent graft introducer for intraluminal deployment of a stent graft (26), the introducer comprising a stent graft release mechanism (6) to allow partial release of the stent graft (26) when carried on the introducer, whereby control of the stent graft can be maintained while allowing access into the lumen of the stent graft from at least one end of the stent graft. The partial release can comprise partial release of one end of the stent graft.Type: GrantFiled: September 22, 2011Date of Patent: June 24, 2014Assignees: The Cleveland Clinic Foundation, Cook Medical Technologies LLCInventors: Roy K. Greenberg, David Ernest Hartley, Michael Lawrence-Brown
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Patent number: 8747455Abstract: An endovascular prosthetic system comprising an prosthetic device with a major lumen extending therethrough, a major wall, at least one opening in the major wall; at least one branch extending into the major lumen of the prosthetic device having a minor lumen, a minor wall, and a fenestration in the minor wall in communication with the major lumen; and at least one guide wire extending through the fenestration and out of the prosthesis through the opening.Type: GrantFiled: August 8, 2008Date of Patent: June 10, 2014Assignee: The Cleveland Clinic FoundationInventor: Roy K. Greenberg
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Patent number: 8709061Abstract: A pre-loaded stent graft delivery device and stent graft, the stent graft delivery device. The stent graft has at least one fenestration or side arm and the fenestration is preloaded with an indwelling guide wire. Indwelling access sheaths are provided within auxiliary lumens of a pusher catheter and dilators are preloaded into the access sheaths along with the indwelling guide wire. A handle assembly at a distal end of the guide wire catheter. The handle includes a multiport manifold with access ports to the auxiliary lumens in the pusher catheter. Upon deployment of the stent graft into the vasculature of a patient, the indwelling guide wire can be used to facilitate catheterization of a side branch or target vessel through the fenestration or be used to stabilize the access sheath during catheterization, advancement of the access sheath into the target vessel and deployment of a covered or uncovered stent therein through the access sheath.Type: GrantFiled: June 6, 2011Date of Patent: April 29, 2014Assignees: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: Roy K. Greenberg, Krasnodar Ivancev, David Ernest Hartley, Werner D. Ducke, Erik Rasmussen
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Patent number: 8663310Abstract: A hybrid stent graft device for treatment of a Type A dissection having a first tubular portion for placement into the ascending aorta and a second tubular portion for extending around the thoracic arch and down the descending aorta is disclosed. The first tubular portion is connectable to the aorta between the sinotubular junction and the brachiocephalic artery so that it essentially replaces the ascending aorta. A temporary bypass tube allows perfusion during an operation. The second tubular portion has an elongate recess outside of the second tubular portion and an aperture defining a fluid flow path into the recess. The recess is intended to engage an outer curve of the thoracic arch to enable blood flow into the arteries of the thoracic arch. An introduction device in combination with the hybrid stent graft described above is also disclosed.Type: GrantFiled: December 14, 2011Date of Patent: March 4, 2014Assignees: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: Roy K. Greenberg, Krasnodar Ivancev, David Ernest Hartley
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Publication number: 20130053945Abstract: A delivery system for an endoluminal device including an introducer, the introducer having a distal end intended to remain outside a patient in use and a proximal end. A stent graft having a first and second end is retained upon the introducer, the stent graft defining a fenestration disposed through a wall of the stent graft between the first and second end. A valve arrangement is disposed within an interior lumen of the stent graft about the fenestration. A retention system including a trigger wire engages and retains the valve arrangement away from the fenestration. The fenestration is in fluid communication with the interior lumen of the stent graft.Type: ApplicationFiled: August 29, 2012Publication date: February 28, 2013Applicant: CLEVELAND CLINIC FOUNDATIONInventors: Roy K. Greenberg, Karl J. West
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Publication number: 20130046371Abstract: A system for facilitating deployment of an endoluminal prosthesis may include a main tubular graft body including a proximal end opening, a distal end opening, a lumen, and a sidewall. A branch may extend from the sidewall and may include a first end opening, a second end opening, and a lumen. A fenestration may be disposed in the sidewall and positioned distal of the second end opening of the branch. A wire segment may include a proximal portion positioned proximal of the proximal end opening and a distal portion positioned distal of the distal end opening. The wire segment extend through the fenestration and through the lumen of the branch in a preloaded configuration.Type: ApplicationFiled: April 26, 2012Publication date: February 21, 2013Applicant: Cook Medical Technologies LLCInventors: Roy K. Greenberg, Karl J. West, Timothy A. Resch, Blayne A. Roeder
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Publication number: 20130046339Abstract: A sealing device is configured to seal a fenestration within a stent graft. In one example, the sealing device has a biasing member that is used to retain a sealing member adjacent to the fenestration to prevent blood from escaping from the stent graft. The biasing member is configured to pull the sealing member against the fenestration to ensure a proper seal.Type: ApplicationFiled: April 24, 2012Publication date: February 21, 2013Inventor: Roy K. Greenberg
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Publication number: 20130041456Abstract: The present embodiments provide a branch vessel prosthesis for placement at least partially between a main vessel and a branch vessel of a patient. The branch vessel prosthesis has a graft including a generally tubular body of a biocompatible material. At least one stent is coupled to a proximal region of the graft, and at least one stent is coupled to a distal region of the graft. The proximal region of the graft includes a generally straight configuration in an expanded deployed state that is substantially parallel to a longitudinal axis of a main vessel. The distal region of the graft includes a generally straight configuration in the expanded deployed state that is substantially parallel to a branch vessel. A curvature of a central region varies an angle in which the distal region of the graft is disposed relative to the proximal region.Type: ApplicationFiled: April 18, 2012Publication date: February 14, 2013Inventor: Roy K. Greenberg