Abstract: A reduced pressure delivery system for applying a reduced pressure to a tissue site includes a manifold delivery tube having at least two lumens and a manifold having a plurality of flow channels. The manifold is disposed within a first of the lumens of the manifold delivery tube. A balloon having an inner space and being capable of assuming collapsed and expanded positions is provided. The inner space of the balloon is fluidly connected to a second of the lumens of the manifold delivery tube.

Abstract: The present invention relates generally to the field of treating bacterial infections. More particularly, it relates to an antimicrobial agent and methods of eliminating biofilm and planktonic cells using the antimicrobial agent.

Abstract: A multi-layer reduced pressure delivery apparatus is provided for applying reduced pressure tissue treatment to a tissue site. The multi-layer apparatus includes a tissue contact layer, a release layer, and a manifold layer. The tissue contact layer includes a scaffold adapted to contact the tissue site, the release layer includes a water-soluble polymer and a plurality of flow channels, and the manifold layer includes a distribution manifold. The release layer is positioned between the tissue contact layer and the manifold layer to allow easy release of the manifold layer from the tissue contact layer following the administration of reduced pressure tissue treatment.

Abstract: A biocompatible wound dressing comprised of a pad for insertion substantially into a wound site and a wound drape for sealing enclosure of the foam pad at the wound site. The pad, comprised of a foam or other like material having relatively few open cells in contact with the areas upon which cell growth is to be encouraged so as to avoid unwanted adhesions, but having sufficiently numerous open cells so that drainage and negative pressure therapy may continue unimpaired, is placed in fluid communication with a vacuum source for promotion of fluid drainage, as known in the art. The pad is further comprised of an ultra-low density fused-fibrous ceramic, or a bioabsorbable branched polymer, or cell growth enhancing matrix or scaffolding.

Abstract: The present invention provides skin grafting and devices that comprise a systematic approach to the process of skin grafting, i.e., harvesting, post-excision processing and application of donor skin and pre and post-graft treatment of the recipient site.

Abstract: A multi-layer reduced pressure delivery apparatus is provided for applying reduced pressure tissue treatment to a tissue site. The multi-layer apparatus includes a tissue contact layer, a release layer, and a manifold layer. The tissue contact layer includes a scaffold adapted to contact the tissue site, the release layer includes a hydrogel-forming material and a plurality of flow channels, and the manifold layer includes a distribution manifold. The release layer is positioned between the tissue contact layer and the manifold layer to allow easy release of the manifold layer from the tissue contact layer following the administration of reduced pressure tissue treatment.

Abstract: The present invention provides skin grafting and devices that comprise a systematic approach to the process of skin grafting, i.e., harvesting, post-excision processing and application of donor skin and pre and post-graft treatment of the recipient site.

Abstract: An anisotropic wound drape for treating a wound on a patient includes a flexible sheet for placing over a tissue site. The flexible sheet includes a first isotropic zone, and a second isotropic zone. The first isotropic zone and the second isotropic zone are configured to provide the flexible sheet with anisotropic stretching properties. The anisotropic drape may used as part of a reduced-pressure wound treatment system. Other systems and methods are also presented.

Abstract: A reduced pressure therapy system includes a foam pad having a plurality of passages to distribute a reduced pressure to a tissue. The foam pad includes exterior surfaces and interior surfaces along the plurality of passages. A silver coating uniformly covers the exterior surfaces of the foam pad and the interior surfaces along the passages. A drape is adapted to be positioned over the foam pad to maintain a sealable space over the wound, and a vacuum source is in fluid communication with the sealable space to deliver the reduced pressure to the sealable space.

Abstract: A method, and apparatus for the controlled acceleration, and/or retardation of the body's inflammatory response generally comprises a foam pad for insertion substantially into a wound site, a heating, a cooling pad for application over the wound site, a wound drape or sealing enclosure of the foam pad, the heating, and cooling pad at wound site. The foam pad is placed in fluid communication with a vacuum source for promotion of the controlled acceleration or retardation of the body's inflammatory response. The heating, and cooling provision controls the local metabolic function as part of the inflammatory response.

Abstract: A method, and apparatus for the controlled acceleration, and/or retardation of the body's inflammatory response generally comprises a foam pad for insertion substantially into a wound site, a heating, a cooling pad for application over the wound site, a wound drape or sealing enclosure of the foam pad, the heating, and cooling pad at wound site. The foam pad is placed in fluid communication with a vacuum source for promotion of the controlled acceleration or retardation of the body's inflammatory response. The heating, and cooling provision controls the local metabolic function as part of the inflammatory response.

Abstract: A method and apparatus for the introduction to a wound under negative pressure therapy of a wound healing agent, generally comprises a foam pad (11) for insertion substantially into a wound site (12), and a wound drape (13) for sealing enclosure of the foam pad at the wound site. The foam pad is placed in fluid communication with a vacuum source for promotion of fluid drainage. Additionally, the foam pad is predisposed, through grafting or other techniques known to those of ordinary skill in the art, with basic fibroblast growth factor (bFGF), anti-microbial or other factors, also known to those of ordinary skill in the art, for the promotion of increased wound healing.

Abstract: Methods and systems that incorporate automated or manual control of ventilation and kinetic rotation therapy are provided. In one exemplary embodiment, an artificial ventilator is used to artificially ventilate one of the patient's lungs, the status of the artificially ventilated lung is determined by measuring one or more ventilation status measures, and one or more of the ventilation status measures is used to provide feedback for controlling the positioning of the patient. In some exemplary embodiments, the feedback is used for automated control of the positioning of the patient, while in other exemplary embodiments, the feedback is used as guidance for manual control of the positioning of the patient.

Abstract: The illustrative embodiments described herein are directed to a system and method for administering reduced pressure at a tissue site. The apparatus includes a reduced pressure source. The reduced pressure source generates a reduced pressure. The apparatus includes a tube having a plurality of lumens. The plurality of lumens includes at least one collection lumen. The reduced pressure source applies the reduced pressure to the tissue site through the plurality of lumens such that the at least one collection lumen receives fluid from the tissue site. The at least one collection lumen stores the fluid received from the tissue site.

Abstract: A method of administering a reduced pressure tissue treatment to a tissue site includes percutaneously inserting a tube through a skin tissue of a patient to place a distal end of the tube adjacent the tissue site, the tube having at least one passageway. A balloon associated with the tube is positioned adjacent the tissue site, and the balloon is inflated to dissect and form a void adjacent the tissue site. A manifold having a plurality of flow channels is delivered through the passageway to the tissue site. The manifold is positioned such that at least one of the flow channels is in contact with the tissue site, and a reduced pressure is applied to the tissue site through the flow channels of the manifold.

Abstract: A reduced pressure delivery system for applying a reduced pressure to a tissue site includes a manifold delivery tube having a passageway and a distal end, the distal end configured to be percutaneously inserted and placed adjacent the tissue site. A flowable material is provided and is percutaneously deliverable through the manifold delivery tube to the tissue site. The flowable material is capable of filling a void adjacent the tissue site to create a manifold having a plurality of flow channels in fluid communication with the tissue site. A reduced pressure delivery tube is provided that is capable of fluid communication with the flow channels of the manifold.

Abstract: A reduced pressure delivery system for applying a reduced pressure to a tissue site includes a manifold delivery tube having at least two lumens and a manifold having a plurality of flow channels. The manifold is disposed within a first of the lumens of the manifold delivery tube. A balloon having an inner space and being capable of assuming collapsed and expanded positions is provided. The inner space of the balloon is fluidly connected to a second of the lumens of the manifold delivery tube.

Abstract: A reduced pressure delivery system for applying a reduced pressure to a tissue site is provided. The system includes a manifold having a plurality of flow channels. The manifold is configured to be placed adjacent the tissue site. A first conduit is in fluid communication with the flow channels of the manifold to deliver a reduced pressure to the flow channels. A second conduit is in fluid communication with the flow channels of the manifold and is operably connected to a valve. The valve selectively purges the second conduit with ambient air when the valve is positioned in an open position, and a controller is operably connected to the valve to place the valve in the open position for a selected amount of time at a selected interval during delivery of reduced pressure through the first conduit.

Abstract: A method, and apparatus (10) for the controlled acceleration, and/or retardation of the body's inflammatory response generally comprises a foam pad (11) for insertion substantially into a wound site, a heating, a cooling pad (13) for application over the wound site (12), a wound drape (14) or sealing enclosure of the foam pad (11), the heating, and cooling pad (13) at wound site (12). The foam pad (11) is placed in fluid communication with a vacuum source for promotion of the controlled acceleration or retardation of the body's inflammatory response. The heating, and cooling provision controls the local metabolic function as part of the inflammatory response.

Abstract: A modified vacuum assisted wound closure system adapted for concurrent applications of phototherapy having a foam pad for insertion substantially into the wound site and a wound drape for sealing enclosure of the foam pad at the wound site. The foam pad includes an optical pigtail, whereby desired wavelength of light may be directed into and about the wound site. The foam pad is placed in fluid communication with a vacuum source for promotion of fluid drainage. The foam pad is made of a highly reticulated, open-cell polyurethane or polyether foam for good permeability of wound fluids while under suction and is also embedded with an optical pigtail. The optical pigtail comprises an optical fiber that has been formed to fan into a plurality of sections. The fibers of the most distal fanned sections, which are implanted in the foam pad at its base, are provided with tiny optical slots, oriented away from the foam pad and toward the wound site.