Patents by Inventor Ruby I. Nielsen

Ruby I. Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5631223
    Abstract: Novel compounds of the general composition I, Lactate (1), Glycine (1), Valine (1), Isoleucine (1), pipecolic acid (1), Aspanic acid (1), Tyrosine (1), wherein each amino acid residue independently may occur in L- or D- form, and wherein the number in parenthesis indicates the number of occurrences of each moiety, and derivatives thereof are disclosed. The compounds are producible by aerobic cultivation on suitable nutrient media under suitable conditions of a strain of the fungus Culvularia sp., subsequent recovery of the active component from the fermentation medium, and optionally modifying the active compound to obtain a compound of the desired general composition. Disclosed are also microorganisms capable of producing said compounds, compositions containing said compounds, and the use of such compositions for controlling fungi in crops, and in the preservation of wood, paints, cosmetics, and edible products.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 20, 1997
    Assignee: Novo Nordisk A/S
    Inventors: Jens Breinholt, Ruby I. Nielsen, Georg W. Jensen
  • Patent number: 5569671
    Abstract: Novel compounds of formula I ##STR1## wherein R.sup.1 is independently hydrogen, hydroxy, alkyl with 1 to 6 carbon atoms, acyloxy groups with 1 to 6 carbon atoms, alkyloxy with 1 to 6 carbon atoms or from 1 to 5 sugar moieties; and R.sup.2 is independently hydrogen, or alkyl with 1 to 6 carbon atoms.The compounds are producible by aerobic cultivation on suitable nutrient media under suitable conditions of a strain of the fungus Ascochyta sp., subsequent recovery of the active component from the fermentation medium, and optionally modifying the active compound to obtain a compound of the desired formula I.Disclosed is also microorganisms capable of producing said compounds, compositions containing said compounds, and the use of such compositions for controlling fungi in valuable crops, animals, including birds and mammals, and in the preservation of wood, paints and edible products.
    Type: Grant
    Filed: April 24, 1995
    Date of Patent: October 29, 1996
    Assignee: Novo Nordisk A/S
    Inventors: Ruby I. Nielsen, Frank W. Rasmussen
  • Patent number: 5514648
    Abstract: Novel compounds of the general composition I, Lactate (1), Glycine (1), Valine (4), Isoleucine (1), pipecolic acid (1), Aspartic acid (1), Tyrosine (1), wherein each amino acid residue independently may occur in L- or D- form, and wherein the number in parenthesis indicates the number of occurrences of each moiety, and derivatives thereof are disclosed. The compounds are producible by aerobic cultivation on suitable nutrient media under suitable conditions of a strain of the fungus Curvularia sp., subsequent recovery of the active component from the fermentation medium, and optionally modifying the active compound to obtain a compound of the desired general composition. Disclosed are also microorganisms capable of producing said compounds, compositions containing said compounds, and the use of such compositions for controlling fungi in crops, and in the preservation of wood, paints, cosmetics, and edible products.
    Type: Grant
    Filed: August 16, 1993
    Date of Patent: May 7, 1996
    Assignee: Novo Nordisk A/S
    Inventors: Jens Breinholt, Ruby I. Nielsen, Georg W. Jensen
  • Patent number: 5491122
    Abstract: The present invention provides fungicidal and insecticidal active compounds and derivatives thereof, fungicidal and insecticidal compositions comprising said compounds, processes for producing said compounds and the use of said compounds for controlling fungi and/or insects.
    Type: Grant
    Filed: December 7, 1994
    Date of Patent: February 13, 1996
    Assignees: Novo Nordisk A/S, Novo Nordisk Entotech, Inc.
    Inventors: Denise C. Manker, Connie N. Rosendahl, Morten Heide, Torben L. Bachmann, Ruby I. Nielsen
  • Patent number: 5409951
    Abstract: Novel compounds of formula I ##STR1## wherein R.sup.1 is independently hydrogen, hydroxy, alkyl with 1 to 6 carbon atoms, acyloxy groups with 1 to 6 carbon atoms, alkyloxy with 1 to 6 carbon atoms or from 1 to 5 sugar moleties; and R.sup.2 is independently hydrogen, or alkyl with 1 to 6 carbon atoms.The compounds are producible by aerobic cultivation on suitable nutrient media under suitable conditions of a strain of the fungus Ascochyta sp., subsequent recovery of the active component from the fermentation medium, and optionally modifying the active compound to obtain a compound of the desired formula I.Disclosed is also microorganisms capable of producing said compounds, compositions containing said compounds, and the use of such compositions for controlling fungi in valuable crops, animals, including birds and mammals, and in the preservation of wood, paints and edible products.
    Type: Grant
    Filed: July 22, 1993
    Date of Patent: April 25, 1995
    Assignee: Novo Nordisk A/S
    Inventors: Ruby I. Nielsen, Frank W. Rasmussen
  • Patent number: 5288624
    Abstract: The present invention relates to a funcidally active principle (fungicidal agent) obtainable by cultivation of fungi of the genus Phaeoramularia or Cercospora. The principle can be used for controlling fungi in plants and animals, including mammals.
    Type: Grant
    Filed: June 13, 1991
    Date of Patent: February 22, 1994
    Assignee: Novo Nordisk A/S
    Inventor: Ruby I. Nielsen
  • Patent number: 5288627
    Abstract: An endoprotease preparation, comprising an isolated endoprotease is disclosed. The endoprotease is a serine protease, shows immunochemical idenity to a protease derived from Fusarium oxysporum DSM 2672, hydrolyzes the oxidized beta-chain of bovine insulin at the peptide bonds Arg (22)-Gly (23) and Lys (29)-Ala(30), has optimum activity towards casein in the pH range of 8.5-11.0 with nearly constant activity in the pH range, has optimum activity at a temperature of about 45.degree. C., and has an isolectric point of about 9.0-10.0. The preferred microorganism that the enzyme is isolated from is Fusarium oxysporum DSM 2672.
    Type: Grant
    Filed: November 17, 1992
    Date of Patent: February 22, 1994
    Assignee: Novo Nordisk A/S
    Inventors: Ruby I. Nielsen, Dorrit A. Aaslyng, Georg W. Jensen, Palle Schneider