Patents by Inventor Rudolph P. Reckel

Rudolph P. Reckel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4595654
    Abstract: Method and test kit for detecting Clq-containing complexes in human serum containing native serum Cl. The method uses a monoclonal antibody which selectively reacts with human Clq in the presence of native human serum Cl. Preparation of hybridomas generating such antibodies is also disclosed. The method is applicable to detection of autoimmune diseases and AIDS.
    Type: Grant
    Filed: November 7, 1983
    Date of Patent: June 17, 1986
    Assignee: Immunomedics Inc.
    Inventors: Rudolph P. Reckel, Joanne L. Harris, Ralph Wellerson, Jr., Sally M. Shaw, Paul M. Kaplan
  • Patent number: 4427779
    Abstract: Method for detecting circulating immune complexes containing endogenously bound Clq. Capillary tubes are filled with a mixture of Clq coated GPO reagent cells, rabbit anti-Clq antibodies, and precipitate from the biological fluid sample containing immune complexes. The mixture is allowed to react and the tubes read for the presence or absence of agglutination indicative of the absence or presence of said immune complexes respectively.
    Type: Grant
    Filed: May 26, 1982
    Date of Patent: January 24, 1984
    Assignee: Ortho Diagnostic Systems Inc.
    Inventors: Rudolph P. Reckel, Joanne L. Harris
  • Patent number: 4420461
    Abstract: Kit for detecting circulating immune complexes containing endogenously bound Clq. Capillary tubes are filled with a mixture of Clq coated GPO reagent cells, rabbit anti-Clq antibodies, and precipitate from the biological fluid sample containing immune complexes. The mixture is allowed to react and the tubes read for the presence or absence of agglutination indicative of the absence or presence of said immune complexes respectively.
    Type: Grant
    Filed: May 26, 1982
    Date of Patent: December 13, 1983
    Assignee: Ortho Diagnostic Systems Inc.
    Inventors: Rudolph P. Reckel, Joanne L. Harris
  • Patent number: 4140662
    Abstract: A two-step process for achieving a covalent bond between latex polymers and immunological substances, the first of which involves reacting latex particles having a reactive carboxyl group with a diamine in the presence of an appropriate carbodiimide as the condensing agent. The resulting product, which can be designated as the modified latex, is an amide terminating in primary or secondary amino groups. This product is then reacted with the appropriate immunological reagent such as an antigen or antibody modified if necessary to contain amino groups, in the presence of a bifunctional aldehyde to result in the condensation of the amino groups of the immunological reagent to the amino groups of the modified latex via an intermediate aldehyde bridging moiety.
    Type: Grant
    Filed: March 25, 1977
    Date of Patent: February 20, 1979
    Assignee: Ortho Diagnostics, Inc.
    Inventors: Rudolph P. Reckel, Joanne L. Harris
  • Patent number: 4046871
    Abstract: New serological albumin compositions are provided which have greater potentiating capabilities than existing compositions in agglutination reactions of the IgG class of immune globulins. The essential component is at least one covalently bonded serum albumin polymer. The novel polymers are those containing from two to about eight or more monomeric albumin units which are joined to each other through a covalent peptide bond. Serological compositions may be prepared by polymerization of a dilute aqueous albumin solution, quenching of the reaction, precipitation of the products as solids, dissolution of albumin solids with or without separation of polymers in physiological or isotonic solutions. The compositions are useful as diluents for reagent preparation and for titration media, and as antibody detecting media.
    Type: Grant
    Filed: April 8, 1975
    Date of Patent: September 6, 1977
    Assignee: Ortho Diagnostics Inc.
    Inventor: Rudolph P. Reckel