Abstract: The present invention is directed towards systems and methods for generating one or more channels for the organization of content items. A method according to one embodiment comprises selecting a content item and one or more items of metadata for the selected content item. A determination is made to determine if the selected content item should be associated with a given channel on the basis of the metadata. A channel is generated on the basis of the determination, with the selected content item organized in association with the channel.

Abstract: A method comprises generating a first classification model, e.g., metadata-based, for determining whether a video belongs to a category; generating a second classification model, e.g., content-based, for determining whether the video belongs to a category, the first classification model and second classification model being based on different modalities; and generating a fusion model that blends the categorization results of the models. Each classification model may classify the video to multiple categories. During operation, a method obtains a video; uses the first classification model, the second classification model and the fusion model to determine whether the video belongs to a category; and indexes the video in a video index. The method may enable selection of a category corresponding to the video search results. The category may be identified based on a query profile, which may be learned from users' query logs or popular queries and click history.

Abstract: The present invention relates to 4-arylindolinones, as well as pharmaceutical compositions thereof, capable of modulating protein kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation. The present invention also relates to methods for treating protein kinase related disorders.

Abstract: The present invention relates to 4-arylindolinones, as well as pharmaceutical compositions thereof, capable of modulating protein kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation. The present invention also relates to methods for treating protein kinase related disorders.

Abstract: The present invention relates to 4-arylindolinones, as well as pharmaceutical compositions thereof, capable of modulating protein kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation. The present invention also relates to methods for treating protein kinase related disorders.

Abstract: The present invention relates to 4-arylindolinones, as well as pharmaceutical compositions thereof, capable of modulating protein kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation. The present invention also relates to methods for treating protein kinase related disorders.

Abstract: The invention relates to certain indolinone compounds, their method of synthesis, and a combinatorial library consisting of the indolinone compounds of the invention. The invention also relates to methods of modulating the function of protein kinases using indolinone compounds of the invention and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.

Abstract: The invention relates to certain indolinone compounds, their method of synthesis, and a combinatorial library consisting of the indolinone compounds of the invention. The invention also relates to methods of modulating the function of protein kinases using indolinone compounds of the invention and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.