Patents by Inventor Russell DEORAZIO

Russell DEORAZIO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2,5-methano- and 2,5-ethano-tetrahydrobenzazepine derivatives and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
    Patent number: 9045468
    Abstract: The compounds of the present invention are represented by the following 2,5-methano- and 2,5-ethano-tetrahydrobenzazepine derivatives having formula (I): where the carbon atom designated * is in the R or S configuration when n is 1 and the substituents X and R1-R7 are as defined herein.
    Type: Grant
    Filed: August 17, 2011
    Date of Patent: June 2, 2015
    Assignees: Albany Molecular Research, Inc., Bristol-Myers Squibb Company
    Inventors: Peter R. Guzzo, Shuang Liu, Kristen N. Ryan, Bruce F. Molino, Russell DeOrazio, Richard E. Olson, John E. Macor
  • 2,5-Methano- and 2,5-Ethano-Tetrahydrobenzazepine Derivatives And Use Thereof To Block Reuptake Of Norepinephrine, Dopamine, and Serotonin
    Publication number: 20120046271
    Abstract: The compounds of the present invention are represented by the following 2,5-methano- and 2,5-ethano-tetrahydrobenzazepine derivatives having formula (I): where the carbon atom designated * is in the R or S configuration when n is 1 and the substituents X and R1-R7 are as defined herein.
    Type: Application
    Filed: August 17, 2011
    Publication date: February 23, 2012
    Applicants: BRISTOL-MYERS SQUIBB COMPANY, ALBANY MOLECULAR RESEARCH, INC.
    Inventors: Peter R. GUZZO, Shuang LIU, Kristen N. RYAN, Bruce F. MOLINO, Russell DEORAZIO, Richard E. OLSON, John E. MACOR
  • SGLT-2 INHIBITORS, METHODS OF MAKING THEM, AND USES THEREOF
    Publication number: 20110237527
    Abstract: The present invention relates to compounds which are inhibitors of sodium dependent glucose co-transporter-2 (SGLT-2). These compounds are used in the treatment of various disorders, including diabetes, impaired glucose tolerance, insulin resistance, retinopathy, nephropathy, neuropathy, cataracts, hyperglycemia, hyperinsulinemia, hyperchlolesterolemia, elevated blood level of free fatty acids or glycerol, hyperlipidemia, hypertriglyceridemia, obesity, wound healing, tissue ischemia, atherosclerosis, and hypertension. These compounds and compositions are also useful for treating and preventing kidney stones, hyperuricemia, gout, and hyponatremia. Methods of making these compounds are also described in the present invention.
    Type: Application
    Filed: March 21, 2011
    Publication date: September 29, 2011
    Applicant: ALBANY MOLECULAR RESEARCH, INC.
    Inventors: Shuang LIU, Cheng GUO, Min HU, Douglas B. KITCHEN, Peter R. GUZZO, Russell DEORAZIO