Abstract: A transmitting device can compress a packet prior to transmitting the packet to a receiving device, which then decompresses the packet. The packet can be combined into a single combined packet with other packets within a transmission queue of the same type and that refer to consecutive memory block addresses. A header of the packet can be replaced with a reduced-size header including a sequence number and a flag indicating the header has been replaced with the reduced-size header, if the packet has a consecutive memory block address to that of the most recently transmitted packet. A payload of the packet may also be compressed.