Abstract: The invention relates to methods useful in the treatment of benign, premalignant and malignant solid tumors, especially those of the skin comprising methods for the administration of pharmacologically active compositions containing catecholic butanes. The invention also relates to methods of preventing the occurrence of tumors, and the use of catecholic butanes as a sunscreening agent. The preferred catecholic butane is nordihydroguaiaretic acid. The preferred methods of application of the compositions containing catecholic butanes are by topical application and intratumor injection.

Abstract: The present invention provides new compositions comprising catecholic butanes and ionic zinc. The invention also relates to pharmacologically active compositions comprising said new compositions, which are useful in the treatment of benign, premalignant and malignant solid tumors, especially those of the skin. The ionic zinc may be in the form of a zinc salt, and the preferred catecholic butane is nordihydroguaiaretic acid.

Abstract: A mixture of an extract from a plant belonging to the Zygophyllaceae family containing phenolic compositions and a nonalkali metal salt is useful as a pharmaceutical agent, for example, in the treatment of cancer, nonmalignant tumors, osteomyelitis, psoriasis and warts.

Abstract: The growth of micro-organisms, including cells, molds, yeasts, bacteria and the like, under conditions of substantially zero gravity, is accomplished in a closed system maintained within a space vehicle in orbital flight including mechanisms for supplying oxygen of an optimum bubble size range and number density of bubbles, to a suitable culture medium, continuously dialyzing the culture medium of the micro-organism suspension against an excess of fresh culture medium to remove metabolites and replenish nutrients, supplying additional growth medium to the culture as needed, and recovering desired products of the fermentation, including, for example, enzymes, steroids and pharmaceuticals.