Patents by Inventor Ruth Elizabeth TenBrink

Ruth Elizabeth TenBrink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INDAZOLE DERIVATIVES
    Publication number: 20110028447
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for the treatment of a condition mediated by CB1 receptor activity in a mammalian subject including a human, which comprises administering to a mammal in need of such treatment a therapeutically effective amount of the compound of formula (I) wherein R1, R2 and R3 are as defined in this specification.
    Type: Application
    Filed: February 26, 2009
    Publication date: February 3, 2011
    Inventors: Ingrid Price Buchler, Michael Joseph Hayes, Shridhar Gajanan Hegde, Susan Landis Hockerman, Darin Eugene Jones, Steven Wade Kortum, Joseph Gerace Rico, Ruth Elizabeth TenBrink, Kun Ken Wu
  • 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors
    Publication number: 20080200475
    Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: (I) wherein A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2a, Rx, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
    Type: Application
    Filed: March 20, 2006
    Publication date: August 21, 2008
    Inventors: Michael Dalton Ennis, Steven Wade Kortum, Ruth Elizabeth Tenbrink
  • 4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors
    Publication number: 20080194590
    Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) wherein A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, X2k, R2l, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
    Type: Application
    Filed: March 20, 2006
    Publication date: August 14, 2008
    Inventors: Michael Dalton Ennis, Steven Wade Kortum, Ruth Elizabeth Tenbrink
  • 4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors
    Publication number: 20080176857
    Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: wherein A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
    Type: Application
    Filed: March 20, 2006
    Publication date: July 24, 2008
    Inventors: Michael Dalton Ennis, Steven Wade Kortum, Ruth Elizabeth Tenbrink
  • Oxazinocarbazoles for the treatment of CNS diseases
    Patent number: 6932961
    Abstract: The present invention provides isotopically labeled oxazinocarbazole derivatives having a ring connecting position 8 (C-8) and position 9 (N-9), and more specifically, provides compounds of formula (I) wherein R1, R2, R3 and R4 are described herein. These compounds are useful in the diagnostic analysis of diseases wherein modulation of 5-HT activity is desired.
    Type: Grant
    Filed: April 8, 2003
    Date of Patent: August 23, 2005
    Assignee: Pharmacia & Upjohn Company
    Inventors: Ruth Elizabeth TenBrink, Kalpana M. Merchant, Timothy J. McCarthy
  • Oxazinocarbazoles for the treatment of CNS diseases
    Patent number: 6821970
    Abstract: The present invention provides oxazinocarbazole derivatives having a ring connecting position 8 (C-8) and position 9 (N-9), and more specifically, provides compounds of formula (I) wherein R1, R2, R3 and R4 are described herein. These compounds are 5-HT ligands, and are useful for treating diseases wherein modulation of 5-HT activity is desired.
    Type: Grant
    Filed: May 16, 2002
    Date of Patent: November 23, 2004
    Assignee: Pharmacia & Upjohn Company
    Inventor: Ruth Elizabeth TenBrink
  • Aminoalkoxy carbazoles for the treatment of cns diseases
    Patent number: 6514968
    Abstract: The present invention provides aminoalkoxy carbazole derivatives, and more specifically, provides compounds of formula (I) wherein R1, R2, R3, R4, R8 and R9 are described herein. These compounds are 5-HT ligands, and are useful for treating diseases wherein modulation of 5-HT activity is desired.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: February 4, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventor: Ruth Elizabeth TenBrink
  • Oxazinocarbazoles for the treatment of CNS diseases
    Publication number: 20020169317
    Abstract: The present invention provides oxazinocarbazole derivatives having a ring connecting position 8 (C-8) and position 9 (N-9), and more specifically, provides compounds of formula (I) wherein R1, R2, R3 and R4 are described herein.
    Type: Application
    Filed: May 16, 2002
    Publication date: November 14, 2002
    Inventor: Ruth Elizabeth TenBrink
  • Oxazinocarbazoles for the treatment of CNS diseases
    Patent number: 6448397
    Abstract: The present invention provides oxazinocarbazole derivatives having a ring connecting position 8 (C-8) and position 9 (N-9), and more specifically, provides compounds of formula (I) wherein R1, R2, R3 and R4 are described herein. These compounds are 5-HT ligands, and are useful for treating diseases wherein modulation of 5-HT activity is desired.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: September 10, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventor: Ruth Elizabeth TenBrink
  • Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac diseases
    Patent number: 6013654
    Abstract: The present invention relates to imidazo[1,2-a]pyridine compounds of formula I which are dopamine D-4 antagonists and useful as anti-psychotic agents.
    Type: Grant
    Filed: December 30, 1998
    Date of Patent: January 11, 2000
    Assignee: Pharmacia & Upjohn Company
    Inventor: Ruth Elizabeth TenBrink
  • Imidazo?1,5-a!quinolines for treatment of anxiety and sleep disorders
    Patent number: RE35840
    Abstract: The present invention is to imidazo?1,5-a!quinolines (I) which are useful pharmaceutical agents for the treatment of anxiety, sleep disorders, panic states, convulsions and muscle disorders.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: July 7, 1998
    Assignee: Pharmacia & Upjohn Company
    Inventors: Eric Jon Jacobsen, Ruth Elizabeth TenBrink