Patents by Inventor Ruth PHILLIPS

Ruth PHILLIPS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11926827
    Abstract: Provided herein are MAPT RNAi agents and compositions comprising a MAPT RNAi agent. Also provided herein are methods of using the MAPT RNAi agents or compositions comprising a MAPT RNAi agent for reducing MAPT expression and/or treating tauopathy in a subject.
    Type: Grant
    Filed: May 3, 2023
    Date of Patent: March 12, 2024
    Assignee: ELI LILLY AND COMPANY
    Inventors: Barbara Calamini, Sarah Katharina Fritschi, Rebecca Ruth Miles, Andrew Peter McCarthy, Douglas Raymond Perkins, Keith Geoffrey Phillips, Kaushambi Roy, Isabel Cristina Gonzalez Valcarcel, Jibo Wang, Shih-Ying Wu, Jeremy S. York
  • Patent number: 11819313
    Abstract: Continuous temperature monitors can be used to collect frequent temperature data over large periods of time. A machine learning system trained with collected temperature data can be used to predict future temperature data for patients. Such predictions can be clinically beneficial for disease states in which fever can be fatal, particularly for those fevers having fast onset. For example, patients undergoing chimeric antigen receptor T-cell (CAR-T) therapy may suffer fevers caused by cytokine release syndrome (CRS). Accordingly, a continuous temperature monitor is used to collect temperature data from CAR-T patients with high risk of CRS (or like patients with high fever risk), and the collected temperature data processed by a machine learning system to predict the patient's future temperature profiles. Results of analysis of the predicted temperature profiles may then be provided to the patient and/or clinician.
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: November 21, 2023
    Assignee: BLUE SPARK INNOVATIONS, LLC
    Inventors: John Gannon, Matt Ream, Frank Feddrix, Ruth Phillips, Adam Perer, Sashi Kolli
  • Publication number: 20210100454
    Abstract: Continuous temperature monitors can be used to collect frequent temperature data over large periods of time. A machine learning system trained with collected temperature data can be used to predict future temperature data for patients. Such predictions can be clinically beneficial for disease states in which fever can be fatal, particularly for those fevers having fast onset. For example, patients undergoing chimeric antigen receptor T-cell (CAR-T) therapy may suffer fevers caused by cytokine release syndrome (CRS). Accordingly, a continuous temperature monitor is used to collect temperature data from CAR-T patients with high risk of CRS (or like patients with high fever risk), and the collected temperature data processed by a machine learning system to predict the patient's future temperature profiles. Results of analysis of the predicted temperature profiles may then be provided to the patient and/or clinician.
    Type: Application
    Filed: October 7, 2020
    Publication date: April 8, 2021
    Inventors: John GANNON, Matt REAM, Frank FEDDRIX, Ruth PHILLIPS, Adam PERER, Sashi KOLLI