Patents by Inventor Ruth Yu
Ruth Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240101962Abstract: The invention features pancreatic islet and pancreatic organoids, and cell cultures and methods that are useful for the rapid and reliable generation of pancreatic islet and pancreatic islet organoids. The invention also features methods of treating pancreatic diseases and methods of identifying agents that are useful for treatment of pancreatic diseases, such as type 2 diabetes and pancreatic cancer, using the pancreatic islet and pancreatic organoids of the invention.Type: ApplicationFiled: June 23, 2023Publication date: March 28, 2024Applicant: Salk Institute for Biological StudiesInventors: Ronald EVANS, Michael DOWNES, Annette ATKINS, Eiji YOSHIHARA, Ruth YU
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Patent number: 11760977Abstract: The invention features pancreatic islet and pancreatic organoids, and cell cultures and methods that are useful for the rapid and reliable generation of pancreatic islet and pancreatic islet organoids. The invention also features methods of treating pancreatic diseases and methods of identifying agents that are useful for treatment of pancreatic diseases, such as type 2 diabetes and pancreatic cancer, using the pancreatic islet and pancreatic organoids of the invention.Type: GrantFiled: May 24, 2017Date of Patent: September 19, 2023Assignee: SALK INSTITUTE FOR BIOLOGICAL STUDIESInventors: Ronald Evans, Michael Downes, Annette Atkins, Eiji Yoshihara, Ruth Yu
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Patent number: 11685901Abstract: The invention features pancreatic islet and pancreatic organoids, and cell cultures and methods that are useful for the rapid and reliable generation of pancreatic islet and pancreatic islet organoids. The invention also features methods of treating pancreatic diseases and methods of identifying agents that are useful for treatment of pancreatic diseases, such as type 2 diabetes and pancreatic cancer, using the pancreatic islet and pancreatic organoids of the invention.Type: GrantFiled: March 28, 2022Date of Patent: June 27, 2023Assignee: Salk Institute for Biological StudiesInventors: Ronald Evans, Michael Downes, Annette Atkins, Eiji Yoshihara, Ruth Yu
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Publication number: 20220220446Abstract: The invention features pancreatic islet and pancreatic organoids, and cell cultures and methods that are useful for the rapid and reliable generation of pancreatic islet and pancreatic islet organoids. The invention also features methods of treating pancreatic diseases and methods of identifying agents that are useful for treatment of pancreatic diseases, such as type 2 diabetes and pancreatic cancer, using the pancreatic islet and pancreatic organoids of the invention.Type: ApplicationFiled: March 28, 2022Publication date: July 14, 2022Applicant: Salk Institute for Biological StudiesInventors: Ronald EVANS, Michael DOWNES, Annette ATKINS, Eiji YOSHIHARA, Ruth YU
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Publication number: 20210363490Abstract: The invention features cells, islet-like cells, pancreatic islets and organoids (e.g., human islet-like organoids or HILOs), as well as cell cultures and methods that are useful for the rapid and reliable generation of cells and organoids, such as pancreatic islets and organoids, that are sustainable in vivo and that evade immune detection, rejection and autoimmunity. The invention also features methods of treating pancreatic diseases, such as type 2 diabetes, and pancreatic cancer, using the cells, islet-like cells, pancreatic islets and organoids (e.g., HILOs) that are designed to modulate the activity of immune cells that would otherwise react against them.Type: ApplicationFiled: October 11, 2019Publication date: November 25, 2021Applicant: SALK INSTITUTE FOR BIOLOGICAL STUDIESInventors: Eiji YOSHIHARA, Ruth YU, Michael DOWNES, Ronald EVANS, Annette ATKINS
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Publication number: 20190211310Abstract: The invention features pancreatic islet and pancreatic organoids, and cell cultures and methods that are useful for the rapid and reliable generation of pancreatic islet and pancreatic islet organoids. The invention also features methods of treating pancreatic diseases and methods of identifying agents that are useful for treatment of pancreatic diseases, such as type 2 diabetes and pancreatic cancer, using the pancreatic islet and pancreatic organoids of the invention.Type: ApplicationFiled: May 24, 2017Publication date: July 11, 2019Applicant: SALK INSTITUTE FOR BIOLOGICAL STUDIESInventors: RONALD EVANS, MICHAEL DOWNES, ANNETTE ATKINS, EIJI YOSHIHARA, RUTH YU
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Patent number: 8158224Abstract: A housing (100, 300, 600, 700) for storing and protecting items comprises a photoreactive material (106) that selectively and irreversibly changes colors upon exposure to activating radiation (124, 324); and an ultraviolet attenuation coating (102, 702) disposed over the photoreactive material (106). Radiation (124, 324) is selectively applied to the photoreactive material (106) to irreversibly change the color of the photoreactive material (106) and therefore the housing (100, 300, 600, 700). An optional patterned layer (332) may be disposed between the photoreactive material (106) and the selective application of radiation (124, 324), and a background color (108) may be included, to affect the visual presentation of the housing (100, 300, 600, 700).Type: GrantFiled: April 29, 2008Date of Patent: April 17, 2012Assignee: Motorola Mobility, Inc.Inventors: Ruth Yu-Ai Zhang, Roger Ady, Rick Latella, Louis J. Lundell, Manuel Oliver
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Publication number: 20100062178Abstract: An apparatus and method are provided for forming one dimensional nanostructures. The method comprises ink jet printing (52) a plurality of catalyst particles (36) on a substrate (32). A gas (20) is applied (54) to the catalyst particles (36) while simultaneously applying (56) microwave radiation (38).Type: ApplicationFiled: November 20, 2006Publication date: March 11, 2010Inventors: Ruth Yu-Ai Y. Zhang, George N. Maracas, Larry A. Nagahara
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Publication number: 20090269524Abstract: A housing (100, 300, 600, 700) for storing and protecting items comprises a photoreactive material (106) that selectively and irreversibly changes colors upon exposure to activating radiation (124, 324); and an ultraviolet attenuation coating (102, 702) disposed over the photoreactive material (106). Radiation (124, 324) is selectively applied to the photoreactive material (106) to irreversibly change the color of the photoreactive material (106) and therefore the housing (100, 300, 600, 700). An optional patterned layer (332) may be disposed between the photoreactive material (106) and the selective application of radiation (124, 324), and a background color (108) may be included, to affect the visual presentation of the housing (100, 300, 600, 700).Type: ApplicationFiled: April 29, 2008Publication date: October 29, 2009Applicant: MOTOROLA, INC.Inventors: Ruth Yu-Ai Zhang, Roger Ady, Rick Latella, Louis J. Lundell, Manuel Oliver
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Patent number: 7361579Abstract: A method of fabricating a nanotube structure which includes providing a substrate, providing a mask region positioned on the substrate, patterning and etching through the mask region to form at least one trench, depositing a conductive material layer within the at least one trench, depositing a solvent based nanoparticle catalyst onto the conductive material layer within the at least one trench, removing the mask region and subsequent layers grown thereon using a lift-off process, and forming at least one nanotube electrically connected to the conductive material layer using chemical vapor deposition with a methane precursor.Type: GrantFiled: May 18, 2006Date of Patent: April 22, 2008Assignee: Motorola, Inc.Inventors: Ruth Yu-Ai Zhang, Raymond K. Tsui, John Tresek, Jr., Adam M. Rawlett
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Patent number: 7074699Abstract: A method of fabricating a nanotube structure which includes providing a substrate, providing a mask region positioned on the substrate, patterning and etching through the mask region to form at least one trench, depositing a conductive material layer within the at least one trench, depositing a solvent based nanoparticle catalyst onto the conductive material layer within the at least one trench, removing the mask region and subsequent layers grown thereon using a lift-off process, and forming at least one nanotube electrically connected to the conductive material layer using chemical vapor deposition with a methane precursor.Type: GrantFiled: December 18, 2003Date of Patent: July 11, 2006Assignee: Motorola, Inc.Inventors: Ruth Yu-Ai Zhang, Raymond K. Tsui, John Tresek, Jr., Adam M. Rawlett
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Publication number: 20060040321Abstract: In accordance with the present invention, there are provided methods for identifying compounds which modulate the activity of TLX. Such compounds will find use in a wide variety of applications, e.g., methods for relieving TLX-mediated transcription repression and/or inducing processes mediated by TLX, methods for inhibiting processes mediated by TLX, methods for promoting stem cell differentiation in a system in need thereof, and the like. In accordance with additional aspects of the present invention, there are provided methods for identifying compounds which modulate the expression of TLX. Such compounds will find use in a variety of applications, e.g.Type: ApplicationFiled: March 31, 2005Publication date: February 23, 2006Inventors: Yanghong Shi, Ruth Yu, Fred Gage, Ronald Evans
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Patent number: 6764874Abstract: A method of fabricating a nanotube structure which includes providing a substrate, depositing a supporting layer and an active catalyst film layer onto the substrate, and forming at least one nanotube on the surface of the substrate using a reaction chamber having a growth temperature of less than 850° C.Type: GrantFiled: January 30, 2003Date of Patent: July 20, 2004Assignee: Motorola, Inc.Inventors: Ruth Yu-Ai Zhang, Islamshah Amlani, Jeffrey H. Baker
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Publication number: 20040132269Abstract: A method of fabricating a nanotube structure which includes providing a substrate, providing a mask region positioned on the substrate, patterning and etching through the mask region to form at least one trench, depositing a conductive material layer within the at least one trench, depositing a solvent based nanoparticle catalyst onto the conductive material layer within the at least one trench, removing the mask region and subsequent layers grown thereon using a lift-off process, and forming at least one nanotube electrically connected to the conductive material layer using chemical vapor deposition with a methane precursor.Type: ApplicationFiled: December 18, 2003Publication date: July 8, 2004Inventors: Ruth Yu-Al Zhang, Raymond K. Tsui, John Tresek, Adam M. Rawlett
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Patent number: 6689674Abstract: A method of fabricating a nanotube structure which includes providing a substrate, providing a mask region positioned on the substrate, patterning and etching through the mask region to form at least one trench, depositing a conductive material layer within the at least one trench, depositing a solvent based nanoparticle catalyst onto the conductive material layer within the at least one trench, removing the mask region and subsequent layers grown thereon using a lift-off process, and forming at least one nanotube electrically connected to the conductive material layer using chemical vapor deposition with a methane precursor.Type: GrantFiled: May 7, 2002Date of Patent: February 10, 2004Assignee: Motorola, Inc.Inventors: Ruth Yu-ai Zhang, Raymond K. Tsui, John Tresek, Jr., Adam M. Rawlett
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Publication number: 20030211322Abstract: A method of fabricating a nanotube structure which includes providing a substrate, providing a mask region positioned on the substrate, patterning and etching through the mask region to form at least one trench, depositing a conductive material layer within the at least one trench, depositing a solvent based nanoparticle catalyst onto the conductive material layer within the at least one trench, removing the mask region and subsequent layers grown thereon using a lift-off process, and forming at least one nanotube electrically connected to the conductive material layer using chemical vapor deposition with a methane precursor.Type: ApplicationFiled: May 7, 2002Publication date: November 13, 2003Inventors: Ruth Yu-ai Zhang, Raymond K. Tsui, John Tresek, Adam M. Rawlett