Abstract: Provided herein are compounds of the Formula I: and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, wherein R1, R2, R9, X1 and G are as defined herein, which are inhibitors of one or more TAM kinases and/or c-Met kinase, and are useful in the treatment and prevention of diseases which can be treated with a TAM kinase inhibitor and/or a c-Met kinase inhibitor.

Abstract: In a method for applying deterministic logic to select resources for resource genomes in a genetic algorithm, a logic engine identifies resources associated with an objective and an overall task population to be completed by one or more of the identified resources. The logic engine then selects a deterministic logical framework from one or more deterministic logical frameworks based on the objective. Following the selection of a deterministic logical framework, the logic engine selects one or more resources from the one or more identified resources based on the selected deterministic logical framework. The logic engine compiles the one or more selected resources into a resource genome, assigns one or more tasks from the task population to the one or more selected resources, and sends instructions to the one or more selected resources to execute the one or more tasks. The logic engine determines a value score for the resource genome.

Abstract: A diesel exhaust treatment system for treating exhaust gas from a diesel engine comprising at least one diesel oxidation catalyst (DOC), at least one diesel particulate filter (DPF), at least one diesel exhaust fluid mixing chamber and at least one selective catalytic reduction converter (SCR). In one desirable embodiment, two DOCs, two DPFs, two SCRs, and two diesel exhaust fluid mixing chambers are arranged in parallel. The disclosed system is configured to reduce back pressure and increase urea vaporization while effectively using available space and providing improved access to components. The system can be coupled to a vehicle frame rail, such as the frame rail of a heavy duty truck.

Abstract: Compositions and methods for editing, e.g., altering a DNA sequence, within a LAG3 gene are provided. Compositions and methods for immunotherapy are provided.

Abstract: Compositions and methods for editing, e.g., altering a DNA sequence, within a 2B4 gene are provided. Compositions and methods for immunotherapy are provided.

Abstract: Compositions and methods for editing, e.g., altering a DNA sequence, within a TIM3 gene are provided. Compositions and methods for immunotherapy are provided.

Abstract: A system, method, and graphical user interface for playing games and/or executing applications on a tablet-based client. One embodiment of a graphical user interface (GUI) for playing a video game on a tablet-based client device comprises: a virtual controller rendered on a display of the tablet computer, the virtual controller substantially mimicking the control provided by a thumb stick of a physical game controller and providing omnidirectional, free-form movement in a synchronous direction in which a user moves a finger on the display of the tablet-based client.

Abstract: A system, method, and graphical user interface for playing games and/or executing applications on a tablet-based client. One embodiment of a graphical user interface (GUI) for playing a video game on a tablet-based client device comprises: a virtual controller rendered on a display of the tablet computer, the virtual controller substantially mimicking the control provided by a thumb stick of a physical game controller and providing omnidirectional, free-form movement in a synchronous direction in which a user moves a finger on the display of the tablet-based client.

Abstract: The invention provides anti-MIC antibodies and methods of using the same.

Abstract: A multi-line electrical assembly that includes a multi-line cable (14), including a multiplicity of insulated conductive wires (59); and a multi-line electrical plug (16), physically connected to the cable. The plug has a housing (56) and a plurality of spaced-apart printed circuit hoards (PCBs, 48), housed in the housing and having a first end (47) that is connected to the cable and having a second end (46), separated from the first end. Further, the PCBs bear a plurality of conductive traces (50), at least some of the traces being electrically connected to the wires proximal to the first end. The traces terminate proximal to the second end.

Abstract: A diesel exhaust treatment system for treating exhaust gas from a diesel engine comprising at least one diesel oxidation catalyst (DOC), at least one diesel particulate filter (DPF), at least one diesel exhaust fluid mixing chamber and at least one selective catalytic reduction converter (SCR). In one desirable embodiment, two DOCs, two DPFs, two SCRs, and two diesel exhaust fluid mixing chambers are arranged in parallel. The disclosed system is configured to reduce back pressure and increase urea vaporization while effectively using available space and providing improved access to components. The system can be coupled to a vehicle frame rail, such as the frame rail of a heavy duty truck.

Abstract: A diesel exhaust treatment system for treating exhaust gas from a diesel engine comprising at least one diesel oxidation catalyst (DOC), at least one diesel particulate filter (DPF), at least one diesel exhaust fluid mixing chamber and at least one selective catalytic reduction converter (SCR). In one desirable embodiment, two DOCs, two DPFs, two SCRs, and two diesel exhaust fluid mixing chambers are arranged in parallel. The disclosed system is configured to reduce back pressure and increase urea vaporization while effectively using available space and providing improved access to components. The system can be coupled to a vehicle frame rail, such as the frame rail of a heavy duty truck.

Abstract: A diesel exhaust treatment system for treating exhaust gas from a diesel engine comprising at least one diesel oxidation catalyst (DOC), at least one diesel particulate filter (DPF), at least one diesel exhaust fluid mixing chamber and at least one selective catalytic reduction converter (SCR). In one desirable embodiment, two DOCs, two DPFs, two SCRs, and two diesel exhaust fluid mixing chambers are arranged in parallel. The disclosed system is configured to reduce back pressure and increase urea vaporization while effectively using available space and providing improved access to components. The system can be coupled to a vehicle frame rail, such as the frame rail of a heavy duty truck.

Abstract: A system, method, and graphical user interface for playing games and/or executing applications on a tablet-based client. One embodiment of a graphical user interface (GUI) for playing a video game on a tablet-based client device comprises: a virtual controller rendered on a display of the tablet computer, the virtual controller substantially mimicking the control provided by a thumb stick of a physical game controller and providing omnidirectional, free-form movement in a synchronous direction in which a user moves a finger on the display of the tablet-based client.

Abstract: A system, method, and graphical user interface for playing games and/or executing applications on a tablet-based client. One embodiment of a graphical user interface (GUI) for playing a video game on a tablet-based client device comprises: a virtual controller rendered on a display of the tablet computer, the virtual controller substantially mimicking the control provided by a thumb stick of a physical game controller and providing omnidirectional, free-form movement in a synchronous direction in which a user moves a finger on the display of the tablet-based client.

Abstract: A system, method, and graphical user interface for playing games and/or executing applications on a tablet-based client. One embodiment of a graphical user interface (GUI) for playing a video game on a tablet-based client device comprises: a virtual controller rendered on a display of the tablet computer, the virtual controller substantially mimicking the control provided by a thumb stick of a physical game controller and providing omnidirectional, free-form movement in a synchronous direction in which a user moves a finger on the display of the tablet-based client.

Abstract: The invention provides anti-MIC antibodies and methods of using the same.

Abstract: A system, method, and graphical user interface for playing games and/or executing applications on a tablet-based client. One embodiment of a graphical user interface (GUI) for playing a video game on a tablet-based client device comprises: a virtual controller rendered on a display of the tablet computer, the virtual controller substantially mimicking the control provided by a thumb stick of a physical game controller and providing omnidirectional, free-form movement in a synchronous direction in which a user moves a finger on the display of the tablet-based client.

Abstract: In one aspect, a device includes a processor, a display accessible to the processor, and storage accessible to the processor. The storage bears instructions executable by the processor to present a user interface (UI) on the display and present at least a first option on the display and a second option on the display. The first option is selectable to present at the device, at least a first representation of first user input of a first input type. The second option is selectable to present, at the device, at least a second representation of second user input of a second input type. The first user input and the second user input pertain to the UI, and the first input type is different from the second input type.

Abstract: A multi-line electrical assembly that includes a multi-line cable (14), including a multiplicity of insulated conductive wires (59); and a multi-line electrical plug (16), physically connected to the cable. The plug has a housing (56) and a plurality of spaced-apart printed circuit boards (PCBs, 48), housed in the housing and having a first end (47) that is connected to the cable and having a second end (46), separated from the first end. Further, the PCBs bear a plurality of conductive traces (50), at least some of the traces being electrically connected to the wires proximal to the first end. The traces terminate proximal to the second end.