Abstract: Methods and systems are described for collecting response data, such as electroencephalography data, functional magnetic resonance imaging data, galvanic skin response data, heart rate data, body temperature data, eye tracking data, face tracking data, head tracking data, etc., as users receive a presentation of digital content and then utilizing that response data to dynamically produce or revise other digital content, such as advertisements, to elicit a specific user response and an expected engagement with the digital content, such as the advertisement.