Abstract: Processors, systems and methods are provided for thread level parallel processing. A processor may include a plurality of columns of vector processing units arranged in a two-dimensional column array with a plurality of column stacks placed side-by-side in a first direction and each column stack having two columns stacked in a second direction and a temporary storage buffer. Each column may include a processing element (PE) that has a vector Arithmetic Logic Unit (ALU) to perform arithmetic operations in parallel threads. At a first end of the column array in the first direction, two columns in the column stack are coupled to the temporary storage buffer for one-way data flow. At a second end of the column array in the first direction, two columns are coupled to each other for one-way data flow. The column array and the temporary storage buffer may form a one-way circular data path.

Abstract: Disclosed embodiments concern interleukin receptor associated kinases (IRAK) inhibitors, such as oxazole compounds, and compositions comprising such inhibitors. Also disclosed are methods of making and using the compounds and compositions. The disclosed compounds and/or compositions may be used to treat or prevent an IRAK-associated disease or condition.

Abstract: Color-selective waveguides, methods for fabricating color-selective waveguides, and augmented reality (AR)/mixed reality (MR) applications including color-selective waveguides are described. The color-selective waveguides can advantageously reduce or block stray light entering a waveguide (e.g., red, green, or blue waveguide), thereby reducing or eliminating back-reflection or back-scattering into the eyepiece.

Abstract: The present disclosure relates to antibodies that selectively bind to B-cell maturation antigen (BCMA) and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.

Abstract: A distributed aperture radar system, apparatus, architecture, and method are provided for generating a completed virtual array aperture by using a radar control processing unit to construct a sparse forward-backward matrix from one or more sparse measurement array vectors and to generate beamforming outputs of a completed virtual array aperture by performing forward-backward matrix completion processing of the sparse forward-backward matrix to construct a completed forward-backward matrix by filling holes in the sparse MIMO virtual array aperture to suppress spurious sidelobes caused by holes in the sparse forward-backward matrix, thereby enabling computation of one or more super resolution direction of arrival (DoA) estimation values based on the completed forward-backward matrix.

Abstract: Systems and methods are disclosed to implement an endpoint command invocation system (“ECIS”). In some embodiments, ECIS can quickly dispatch a command to a large number of endpoint components, where the endpoint components are online. ECIS can receive an invocation of a command, which can include the command recipients. In some embodiments, ECIS determines that some of the command recipients are online, while some of the command recipients are offline. ECIS determines connections to the online command recipients based on a connection map, which is updated whenever an endpoint component opens a connection to ask for a command. ECIS can deliver the command to the online command recipients using the connections. ECIS can also deliver the command to dispatch queues corresponding to the offline command recipients, where the dispatch queues store the command as a pending command that can be delivered to their respective command recipients whenever they come online.

Abstract: A method of manufacturing a tower structure includes printing and depositing, via a printhead assembly of an additive printing system, one or more printed layers of a wall of the tower structure. The method also includes unwinding at least one continuous roll of a reinforcement material to form at least one continuous reinforcement ring member layer, the reinforcement material comprising a pultruded polymer material. Further, the method includes placing the at least one continuous reinforcement ring member layer atop the one or more printed layers of the wall of the tower structure. Moreover, the method includes printing and depositing, via the printhead assembly of the additive printing system, one or more additional printed layers of the wall of the tower structure atop the at least one continuous reinforcement ring member layer.

Abstract: Processors, systems and methods are provided for thread level parallel processing. A processor may include a plurality of columns of vector processing units arranged in a two-dimensional column array with a plurality of column stacks placed side-by-side in a first direction and each column stack having two columns stacked in a second direction and a temporary storage buffer. Each column may include a processing element (PE) that has a vector Arithmetic Logic Unit (ALU) to perform arithmetic operations in parallel threads. At a first end of the column array in the first direction, two columns in the column stack are coupled to the temporary storage buffer for one-way data flow. At a second end of the column array in the first direction, two columns are coupled to each other for one-way data flow. The column array and the temporary storage buffer may form a one-way circular data path.

Abstract: A processor may include a plurality of columns of vector processing units arranged in a two-dimensional column array with a plurality of column stacks placed side-by-side in a first direction and each column stack having two columns stacked in a second direction. The processor may further include a memory unit divided into two portions placed on two opposite sides of the column array in the second direction. Each portion may contain two memory blocks placed side-by-side in the first direction. Each memory block may contain two cache blocks placed along a first edge abutting an adjacent memory block and a plurality banks of memory cells placed to space from the first edge in the first direction by the two cache blocks and from a second edge abutting the column array in the second direction by routing channels.

Abstract: Processors, systems and methods are provided for thread level parallel processing. A processor may include a sequencer configured to: decode instructions that include scalar instructions and vector instructions, execute decoded scalar instructions, and package decoded vector instructions as configurations. The processor may further include a plurality of columns of vector processing units coupled to the sequencer. The plurality of columns of vector processing units may include a plurality of processing elements (PEs) and each of the PEs may include a plurality of Arithmetic Logic Units (ALUs). The sequencer may be configured to send the configurations to the plurality of columns of vector processing units.

Abstract: Provided are methods and articles of manufacture for use with cell therapy for the treatment of diseases or conditions, e.g., cancer, including for predicting and treating a toxicity. In some embodiments, the toxicity is a neurotoxicity or cytokine release syndrome (CRS), such as a severe neurotoxicity or a severe CRS. The methods generally involve detecting a marker by assaying a biological sample from a subject that is a candidate for treatment, optionally with a cell therapy, to determine if the subject is at risk for developing the toxicity, such as neurotoxicity or CRS or severe neurotoxicity or severe CRS. In some embodiments, the methods and articles of manufacture further includes a regent for assaying the biological sample and instructions for determining the percentage or number of cells positive for the marker in the biological sample.

Abstract: Semiconductor fabrication component preparation methods are described. In embodiments, the methods include forming a first layer on a surface of the semiconductor fabrication component. The first layer is characterized by a porosity of greater than or about 0.01 vol. %. The methods further include depositing a second layer on the first layer, where the second layer is characterized by a porosity of less than or about 20 vol. %. Treated semiconductor fabrication components are also described. In embodiments, the treated components include a first layer formed in the surface of the semiconductor fabrication component, where the first layer is characterized by a porosity of greater than or about 0.01 vol. %., and a second layer positioned on the first layer, where the second layer is characterized by a porosity of less than or about 20 vol. %.

Abstract: A method of manufacturing a preform, the method including positioning at least one glass tube in a glass outer cladding to form a preform precursor, the glass tube comprising a first open end and a second open end, forming a preform from the preform precursor, and thermally treating at least one of the preform precursor and the preform. The thermally treating including sealing the first open end and the second open end of the glass tube to form a closed tube and heating and/or cooling the glass tube to manipulate gas pressure within the closed glass tube.

Abstract: The present disclosure is directed to embodiments of a tower structure with at least partially additively manufactured, stacked tower sections. Embodiments of the tower structure have a plurality of stacked tower sections, wherein at least one tower section of the plurality of stacked tower sections includes a wall element having one or more printed layers, and a base holding thereon the one or more printed layers. The present disclosure also is directed to a method of manufacturing a tower structure using a stacked tower sections and additive manufacturing. Embodiments of the method include forming a base of poured concrete or cast material, printing and depositing one or more printed layers to form a wall element, and stacking the plurality of tower sections to form the tower structure.

Abstract: Provided herein are compounds, trifunctional antibody products thereof, and methods and pharmaceutical compositions for use in treatment of inflammatory and/or proliferative diseases

Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain low error rate, low phasing rate, or increased incorporation rate for a second generation ffN under reduced incorporation times, as well as methods and kits using the same.

Abstract: Described herein are systems and methods that search videos and other media content to identify items, objects, faces, or other entities within the media content. Detectors identify objects within media content by, for instance, detecting a predetermined set of visual features corresponding to the objects. Detectors configured to identify an object can be trained using a machine learned model (e.g., a convolutional neural network) as applied to a set of example media content items that include the object. The systems comprise an integrated detection unit configured to record media content, identify preferred content, and communicate the identifications of preferred content for storage in a computationally efficient manner.

Abstract: The description relates to resource aware object detection for encoded video streams that can identify frames of the video stream that include an object of interest, such as a human, without decoding the frames.

Abstract: The present disclosure relates to antibodies that selectively bind to CD3 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.

Abstract: Dental appliances and methods for expanding the lower dental arch. The appliances may be removable mandibular expander devices for efficient arch expansion while being comfortable to wear and easy to use. The appliances may include a lingual portion that is shaped and sized to apply an expansion force to lingual surfaces of one or more teeth. The shape and size of the lingual portion may be configured to distribute the forces among posterior and/or anterior teeth.