Abstract: A surgical device includes a housing, a cannula, a driving handle, and a cutting blade. The housing defines a hole in which the cannula that defines a passageway extending from a distal end to a proximal end is disposed. The driving handle is movably coupled to the housing and includes a driving rod slidably received within the passageway. The cutting blade is disposed within the passageway of the cannula and includes a distal end coupled to the distal end of the cannula, a proximal end configured to engage a distal end of the driving rod, and a reversibly deformable blade region disposed between the distal and proximal ends of the cutting blade. The deformable blade region is sized and configured to be received within at least one slot defined by the cannula and bends and straightens in response to movement of the driving handle relative to the housing.

Abstract: The invention is directed toward porous composites for application to a bone defect site to promote new bone growth. The inventive porous composites comprise a biocompatible polymer and a plurality of particles of bone-derived material, inorganic material, bone substitute material or composite material. In certain embodiments, the porous composites are prepared using a method that includes a supercritical fluid (e.g., supercritical carbon dioxide) treatment. The invention also discloses methods of using these composites as bone void fillers.

Abstract: A surgical device includes a housing, a cannula, a driving handle, and a cutting blade. The housing defines a hole in which the cannula that defines a passageway extending from a distal end to a proximal end is disposed. The driving handle is movably coupled to the housing and includes a driving rod slidably received within the passageway. The cutting blade is disposed within the passageway of the cannula and includes a distal end coupled to the distal end of the cannula, a proximal end configured to engage a distal end of the driving rod, and a reversibly deformable blade region disposed between the distal and proximal ends of the cutting blade. The deformable blade region is sized and configured to be received within at least one slot defined by the cannula and bends and straightens in response to movement of the driving handle relative to the housing.