Abstract: The present disclosure includes litter platform support and positioning systems described generally comprising at least one lift column mounted to an interior floor in an emergency vehicle or structure. The lift column is connected to at least one support assembly, the at least one support assembly adapted to receive and position a litter assembly. In some implementations, the support assembly is connected to the lift column and adapted to independently adjust the litter assembly vertically, laterally, longitudinally, and rotate 360°. The litter platform support and positioning system further includes at least one individual motor associated with each lift column which is operatively connected to a drive screw to independently adjust and control the location of each support assembly to individually position a corresponding litter platform assembly.