Abstract: The present invention is intended to provide a compound or a pharmacologically acceptable salt thereof which is useful in the treatment of a tumor through its ROS1 kinase enzyme activity inhibitory effect and NTRK kinase enzyme inhibitory effect. The present invention provides a compound having an imidazo[1,2-b]pyridazine structure represented by the general formula (I) or a pharmacologically acceptable salt thereof, and a pharmaceutical composition comprising the compound. In the formula, R1, G, T, Y1, Y2, Y3, and Y4 are as defined herein.

Abstract: An inside-door-handle device for a vehicle is provided with a base part and a cover. A swinging space is provided between the base part and the cover. The cover has a locking section; the base part has a lock-receiving section. A swing motion of the cover relative to the base part is regulated by the elastic locking between the locking section and the lock-receiving section. If the cover swings relative to the base part due to pushing operation toward the cover, the lock between the locking section and the lock-receiving section is released, and the cover can be separated from the base part.

Abstract: According to an embodiment, a medical image processing apparatus includes an extraction unit, a calculation unit, and a selection unit. The extraction unit extracts an image region having an image element value larger than a predetermined value from a first image of at least one time phase and second images of a plurality of time phases. The calculation unit calculates a feature quantity that fluctuates in accordance with motion of the image region for the first image of at least the one time phase and the second images of the time phases. The selection unit selects the first image and the second image having similar image features of the image region based on the feature quantity from among the first image of at least the one time phase and the second images of the time phases.

Abstract: An ink jet recording apparatus records an image on a recording material by ejecting a first ink composition through at least one first liquid ejecting nozzle having an open end. The ink jet recording apparatus also includes a platen having a surface on which the recording medium is placed. The surface is away from the open end at a distance PG satisfying the relationship 0.5 mm<PG<2.5 mm. The first ink composition that has been ejected through the first liquid ejecting nozzle is split into a main droplet having a flying velocity Vm and at least one satellite droplet including a satellite droplet having a flying velocity Vs. The flying velocities Vm and Vs satisfy the relationship Vm?Vs<3 m/s.

Abstract: A liquid container capable of containing a liquid has a flow passage that is formed in the liquid container and through which the liquid flows, and a filter 166 provided in the middle of the flow passage. The filter 166 inclines in a direction with respect to the horizontal direction.

Abstract: The present invention is intended to provide a compound or a pharmacologically acceptable salt thereof which is useful in the treatment of a tumor through its ROS1 kinase enzyme activity inhibitory effect and NTRK kinase enzyme inhibitory effect. The present invention provides a compound having an imidazo[1,2-b]pyridazine structure represented by the general formula (I) or a pharmacologically acceptable salt thereof, and a pharmaceutical composition comprising the compound. In the formula, R1, G, T, Y1, Y2, Y3, and Y4 are as defined herein.

Abstract: A liquid container capable of containing a liquid has a flow passage that is formed in the liquid container and through which the liquid flows, and a filter 166 provided in the middle of the flow passage. The filter 166 inclines in a direction with respect to the horizontal direction.

Abstract: The present invention is intended to provide a compound or a pharmacologically acceptable salt thereof which is useful in the treatment of a tumor through its ROS1 kinase enzyme activity inhibitory effect and NTRK kinase enzyme inhibitory effect. The present invention provides a compound having an imidazo[1,2-b]pyridazine structure represented by the general formula (I) or a pharmacologically acceptable salt thereof, and a pharmaceutical composition comprising the compound. In the formula, R1, G, T, Y1, Y2, Y3, and Y4 are as defined herein.

Abstract: A printing apparatus includes a first head that forms a first dot group and a second head that forms a second dot group. The first head has a first nozzle row for a first chromatic ink and a second nozzle row for a second chromatic ink. The second head has a third nozzle row for the first chromatic ink and a fourth nozzle row for the second chromatic ink. With respect to at least the first chromatic ink or the second chromatic ink, in a case in which the number of dots that configure dot rows that are lined up in the main scanning direction, is 3500 or more, a rational number, which is expressed using a number of dots included in the first dot group and a number of dots included in the second dot group in the dot rows, is a value other than zero.

Abstract: An ink jet recording apparatus records an image on a recording material by ejecting a first ink composition through at least one first liquid ejecting nozzle having an open end. The ink jet recording apparatus also includes a platen having a surface on which the recording medium is placed. The surface is away from the open end at a distance PG satisfying the relationship 0.5 mm<PG<2.5 mm. The first ink composition that has been ejected through the first liquid ejecting nozzle is split into a main droplet having a flying velocity Vm and at least one satellite droplet including a satellite droplet having a flying velocity Vs. The flying velocities Vm and Vs satisfy the relationship Vm?Vs<3 m/s.

Abstract: A bicycle cleat positioning kit includes a first section and a second section. The first section has a first shoe attachment portion that is configured to be detachably coupled to a first bicycle shoe. The first section being configured to adjustably position a first cleat on a first sole of the first bicycle shoe. The second section has a second shoe attachment portion that is configured to be detachably coupled to a second bicycle shoe different from the first bicycle shoe. The second section being configured to adjustably position a second cleat on a second sole of the second bicycle shoe.

Abstract: An ink jet recording apparatus records an image on a recording material by ejecting a first ink composition through at least one first liquid ejecting nozzle having an open end. The ink jet recording apparatus also includes a platen having a surface on which the recording medium is placed. The surface is away from the open end at a distance PG satisfying the relationship 0.5 mm<PG<2.5 mm. The first ink composition that has been ejected through the first liquid ejecting nozzle is split into a main droplet having a flying velocity Vm and at least one satellite droplet including a satellite droplet having a flying velocity Vs. The flying velocities Vm and Vs satisfy the relationship Vm?Vs<3 m/s.

Abstract: A liquid holding container includes a liquid accommodating chamber, a flow path, and a filter. The liquid accommodating chamber is configured and arranged to hold liquid. The flow path is communicated with the liquid accommodating chamber via a first through hole and a second through hole. The filter is disposed in the flow path. The first through hole and the second through hole are each communicated with the flow path.

Abstract: To reduce the number of nozzles in an unstable state after a nozzle inspection, a fluid discharge device includes a discharge head capable of discharging a fluid from nozzle, a nozzle inspection process for inspecting a state of discharging of the fluid from the nozzle, and a controller for subjecting the nozzle to a pre-process for discharging the fluid under a discharge condition that a nozzle in an unstable state be put into a dot omission state, subsequently discharging the fluid for the sake of inspection, and executing an inspection process by the nozzle inspection part.

Abstract: An inside door handle device includes: a handle base (10) fixed to an inner panel that composes a door interior of an automobile; an opening portion (11) formed of a through hole formed on one side of the handle base (10); an operation recessed portion (12) that has a recessed shape and is arranged adjacent to the opening portion (11) on the other side of the handle base (10); fixation portions (17) formed in the operation recessed portion (12) and fixed to the inner panel; a handle body (20) in which a grip portion (22) located on a tip end side is urged and held onto the operation recessed portion (12) while a base end side is being swingably supported on the opening portion (11) with handle support portions (14a) interposed therebetween; and a support beam (13) protruded on the opening portion (11) and formed into a fixed-fixed beam shape bent into an L-shape.

Abstract: Compounds exhibiting an osteogenesis-promoting action having the general formula (I) or a pharmacologically acceptable salt thereof: wherein A is selected from among a 3- to 10-membered heterocyclyl group, B is selected from among an amino group, and X is selected from N and CH.

Abstract: A fluid ejection device comprising: a first mid-recording flushing unit for ejecting fluid from the plurality of nozzles and carrying out flushing under a first fluid ejection condition during a recording process in accordance with the recording data; and a second mid-recording flushing unit for ejecting the fluid from the nozzles on the head part and carrying out flushing under a second fluid ejection condition in which at least one of the ejection frequency and quantity of the droplets of fluid ejected from the nozzles is greater than with the first fluid ejection condition when the head part is in a recording initiation part of an image that is formed on the recording medium during the recording process.

Abstract: A printing apparatus includes a first head that forms a first dot group and a second head that forms a second dot group. The first head has a first nozzle row for a first chromatic ink and a second nozzle row for a second chromatic ink. The second head has a third nozzle row for the first chromatic ink and a fourth nozzle row for the second chromatic ink. With respect to at least the first chromatic ink or the second chromatic ink, in a case in which the number of dots that configure dot rows that are lined up in the main scanning direction, is 3500 or more, a rational number, which is expressed using a number of dots included in the first dot group and a number of dots included in the second dot group in the dot rows, is a value other than zero.

Abstract: A liquid ejecting apparatus includes a liquid ejecting head having a nozzle that ejects liquid and a pressure chamber in communication with the nozzle. A pressure generator causes pressure fluctuation in the liquid retained in the pressure chamber. The liquid ejecting head is capable of ejecting the liquid from the nozzle as a result of operation of the pressure generator. A driving signal generating section generates a driving signal having an ejection pulse for driving the pressure generator to eject the liquid from the nozzle. The ejection pulse is a voltage waveform four waveform portions having, respectively, voltage levels V1, V2, V3 and V4 that satisfy the following conditions (A) and (B). 0?V3?0.4×V2??(A) 0.

Abstract: Liquid ejecting apparatus and related methods of operation are disclosed. A liquid ejecting apparatus includes an ejecting head having liquid-ejecting nozzles, a platen disposed to support a recording medium and face the ejecting head, a movement section that moves the ejecting head relative to the platen, a heater that heats the platen, a temperature sensor to detect a temperature of the ejecting head, a driving waveform generation section that generates a driving waveform to drive the ejecting head in accordance with the detected temperature, and a liquid ejection control section that supplies the driving waveform to the ejecting head to eject liquid for printing on the recording medium in a printing area. The driving waveform is generated according to a temperature of the ejecting head that is detected when the ejecting head has come to an area outside the printing area.