Patents by Inventor Ryutaro IMAMURA

Ryutaro IMAMURA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11168159
    Abstract: Provided is a zwitterionic polymer that has a zwitterion that includes an effect of improving the stability of proteins. This zwitterionic polymer is a polymeric protein stabilizer that exhibits a protein stabilizing effect even at a small addition amount of addition, and at the same time has an antioxidant capability. Also provided is a method for producing this zwitterionic polymer. This problem is solved by a zwitterionic polymer containing a repeating unit represented by formula (1) and having a number-average molecular weight of 1,000 to 1,000,000. On formula (1), R1 and R2 are each independently selected from a hydrogen atom; linear, branched or cyclic alkyl groups having 1 to 6 carbons; aromatic groups having 6 to 20 carbons; or alkylene groups having 1 to 6 carbons and formed by linking R1 to R2. R3 represents a hydrogen atom or a methyl group).
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: November 9, 2021
    Assignees: NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY, NOF CORPORATION
    Inventors: Hideharu Mori, Ryutaro Imamura
  • Publication number: 20210017309
    Abstract: Provided is a zwitterionic polymer that has a zwitterion that includes an effect of improving the stability of proteins. This zwitterionic polymer is a polymeric protein stabilizer that exhibits a protein stabilizing effect even at a small addition amount of addition, and at the same time has an antioxidant capability. Also provided is a method for producing this zwitterionic polymer. This problem is solved by a zwitterionic polymer containing a repeating unit represented by formula (1) and having a number-average molecular weight of 1,000 to 1,000,000. On formula (1), R1 and R2 are each independently selected from a hydrogen atom; linear, branched or cyclic alkyl groups having 1 to 6 carbons; aromatic groups having 6 to 20 carbons; or alkylene groups having 1 to 6 carbons and formed by linking R1 to R2. R3 represents a hydrogen atom or a methyl group).
    Type: Application
    Filed: December 26, 2018
    Publication date: January 21, 2021
    Applicants: NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY, NOF CORPORATION
    Inventors: Hideharu MORI, Ryutaro IMAMURA
  • Patent number: 10435509
    Abstract: A hetero type monodispersed polyethylene glycol containing a compound represented by the following formula (1): NH2—(CH2CH2O)a—CH2CH2COOH??(1) (in the formula (1), a represents an integer from 6 to 40); wherein any of (A) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol is separated using reverse phase chromatography, (B) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol is separated using cation exchange chromatography, and (C) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol containing a compound represented by the formula (1) shown above is derivatized and separated using anion exchange chromatography satisfy specific relational expressions, respectively.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: October 8, 2019
    Assignees: TOHOKU TECHNO ARCH CO., LTD., NOF CORPORATION
    Inventors: Kazushi Kinbara, Takahiro Muraoka, Adam Marcin Wawro, Tomoyuki Ohtake, Eui-chul Kang, Tomoki Uruga, Ryutaro Imamura
  • Publication number: 20180186931
    Abstract: A hetero type monodispersed polyethylene glycol containing a compound represented by the following formula (1): NH2—(CH2CH2O)a—CH2CH2COOH??(1) (in the formula (1), a represents an integer from 6 to 40); wherein any of (A) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol is separated using reverse phase chromatography, (B) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol is separated using cation exchange chromatography, and (C) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol containing a compound represented by the formula (1) shown above is derivatized and separated using anion exchange chromatography satisfy specific relational expressions, respectively.
    Type: Application
    Filed: June 29, 2016
    Publication date: July 5, 2018
    Applicants: TOHOKU TECHNO ARCH CO., LTD., NOF CORPORATION
    Inventors: Kazushi KINBARA, Takahiro MURAOKA, Marcin Adam WAWRO, Tomoyuki OHTAKE, Eui-chul KANG, Tomoki URUGA, Ryutaro IMAMURA