Patents by Inventor S. Edward Lee

S. Edward Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Viral delivery systems and related manufacture and use
    Publication number: 20040197914
    Abstract: The invention relates to viral delivery systems and methods for infecting cells with viruses. The viral delivery systems may be cryogenically preserved and they may be used in the manufacture of vaccines, polypeptides, and polynucleotides. The invention includes a cryogenically protected viral delivery system for infecting host cells that comprises a cryogenic vessel and a plurality of virally infected cells in admixture with a cryo-protective agent contained in the cryogenic vessel.
    Type: Application
    Filed: November 3, 2003
    Publication date: October 7, 2004
    Applicant: Pfizer Inc.
    Inventors: David J. Wasilko, S. Edward Lee, William R. Hermans
  • Process for production of avermectins
    Patent number: 5583015
    Abstract: Streptomyces avermitilis lacking branched-chain amino acid transaminase activity and/or branched-chain 2-oxo acid dehydrogenase activity, methods for preparation thereof, and use thereof to produce natural and non-natural avermectins useful as parasiticides.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: December 10, 1996
    Assignee: Pfizer Inc.
    Inventors: Edmund W. Hafner, Kelvin S. Holdom, S. Edward Lee
  • Process for production of B avermectins
    Patent number: 5576199
    Abstract: Streptomyces avermitilis lacking branched-chain 2-oxo acid dehydrogenase activity and avermectin B O-methyltransferase activity, method for preparation thereof, and use thereof to produce natural and non-natural B avermectins useful as parasiticides.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: November 19, 1996
    Assignee: Pfizer Inc.
    Inventors: Edmund W. Hafner, Kelvin S. Holdom, S. Edward Lee
  • Cultures for production of B avermectins
    Patent number: 5565359
    Abstract: Streptomyces avermitilis lacking branched-chain 2-oxo acid dehydrogenase activity and avermectin B O-methyltransferase activity, method for preparation thereof, and use thereof to produce natural and non-natural B avermectins useful as parasiticides.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: October 15, 1996
    Assignee: Pfizer Inc.
    Inventors: Edmund W. Hafner, Kelvin S. Holdom, S. Edward Lee
  • Process for production of avermectins and cultures therefor
    Patent number: 5525506
    Abstract: Streptomyces avermitilis lacking branched-chain amino acid transaminase activity and/or branched-chain 2-oxo acid dehydrogenase activity, methods for preparation thereof, and use thereof to produce natural and non-natural avermectins useful as parasiticides.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: June 11, 1996
    Assignee: Pfizer Inc.
    Inventors: Edmund W. Hafner, Kelvin S. Holdom, S. Edward Lee
  • Ethylated avermectins
    Patent number: 5387509
    Abstract: Avermectins wherein one or both of the 3'- and 3"-positions of the oleandrose disaccharide moiety is substituted by an ethoxy rather than a methoxy group, process for their preparation; and their use as antiparasitic agents.
    Type: Grant
    Filed: June 26, 1989
    Date of Patent: February 7, 1995
    Assignee: Pfizer Inc.
    Inventors: Steven J. Hawrylik, S. Edward Lee
  • Cultures for production of avermectins
    Patent number: 5238848
    Abstract: Streptomyces avermitilis lacking branched-chain amino acid transaminase activity and/or branched-chain 2-oxo acid dehydrogenase activity, methods for preparation thereof, and use thereof to produce natural and non-natural avermectins useful as parasiticides.
    Type: Grant
    Filed: February 27, 1991
    Date of Patent: August 24, 1993
    Assignee: Pfizer Inc
    Inventors: Edmund W. Hafner, Kelvin S. Holdom, S. Edward Lee
  • Cultures for production of B avermectins
    Patent number: 5234831
    Abstract: Streptomyces avermitilis lacking branched-chain 2-oxo acid dehydrogenase activity and avermectin B O-methyltransferase activity, method for preparation thereof, and use thereof to produce natural and non-natural B avermectins useful as parasiticides.
    Type: Grant
    Filed: February 26, 1991
    Date of Patent: August 10, 1993
    Assignee: Pfizer Inc
    Inventors: Edmund W. Hafner, Kelvin S. Holdom, S. Edward Lee
  • Non-natural demethylavermectins compositions and method of use
    Patent number: 5077278
    Abstract: Non-natural demethylavermectins useful as parasiticides and process therefor.
    Type: Grant
    Filed: November 30, 1987
    Date of Patent: December 31, 1991
    Assignee: Pfizer Inc.
    Inventors: Edmund W. Hafner, Kelvin S. Holdom, S. Edward Lee