Patents by Inventor S. Michal Jazwinski

S. Michal Jazwinski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lag 1:gene for increasing the longevity of eukaryotes
    Patent number: 5817782
    Abstract: The present invention provides a unique eukaryotic gene, called LAG1, which controls the longevity of eukaryotic cells. According to the present invention, overexpression of LAG1 in older cells has a rejuvenating effect which not only increases cellular life span but also reproductive capacity and cellular tolerance to stress factors such as starvation and low pH. Moreover, the present invention identifies two domains in LAG1 one having a life span limiting function and the other a life span extending function. Hence, according to the present invention, the longevity and tolerance to stress of cells is increased when provided with the wild type polypeptide or mutant LAG1 polypeptides which, for example, lack the "life span limiting domain.
    Type: Grant
    Filed: November 8, 1994
    Date of Patent: October 6, 1998
    Assignee: Research Corporation Technologies, Inc.
    Inventor: S. Michal Jazwinski