Patents by Inventor S. William Stezoski
S. William Stezoski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8628512Abstract: Provided are methods for inducing preservation in a patient and resuscitating that patient. At least three hours of preservation, with successful resuscitation, are realized using the methods described herein. The methods involve flushing a patient with an oxygenated, cold-flush solution, such as normal saline, having an energy source. The patient may be cooled to deep or profound hypothermia to induce preservation. The patient may be resuscitated by warming to from about 33° C. to about 36° C., and then may be slowly warmed over a 24 to 72 hour period to normothermia. Kits for inducing preservation also are provided.Type: GrantFiled: October 8, 2010Date of Patent: January 14, 2014Assignee: University of Pittsburgh—Of the Commonwealth System of Higher EducationInventors: Patrick M Kochanek, Xianren Wu, Samuel Aaron Tisherman, S. William Stezoski, Lyn Yaffe
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Publication number: 20110028961Abstract: Provided are methods for inducing preservation in a patient and resuscitating that patient. At least three hours of preservation, with successful resuscitation, are realized using the methods described herein. The methods involve flushing a patient with an oxygenated, cold-flush solution, such as normal saline, having an energy source. The patient may be cooled to deep or profound hypothermia to induce preservation. The patient may be resuscitated by warming to from about 33° C. to about 36° C., and then may be slowly warmed over a 24 to 72 hour period to normothermia. Kits for inducing preservation also are provided.Type: ApplicationFiled: October 8, 2010Publication date: February 3, 2011Inventors: Patrick M. Kochanek, Xianren Wu, Samuel Aaron Tisherman, S. William Stezoski, Lyn Yaffe
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Publication number: 20100121273Abstract: Provided are methods for inducing preservation in a patient and resuscitating that patient. At least three hours of preservation, with successful resuscitation, are realized using the methods described herein. The methods involve flushing a patient with an oxygenated, cold-flush solution, such as normal saline, having an energy source. The patient may be cooled to deep or profound hypothermia to induce preservation. The patient may be resuscitated by warming to from about 33° C. to about 36° C., and then may be slowly warmed over a 24 to 72 hour period to normothermia. Kits for inducing preservation also are provided.Type: ApplicationFiled: June 21, 2006Publication date: May 13, 2010Inventors: Patrick M. Kochanek, Xianren Wu, Samuel Aaron Tisherman, S. William Stezoski, Lyn Yaffe
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Patent number: 6475186Abstract: A cardiopulmonary bypass system includes an aortic balloon cannula and a fluid flow cannula configured for connection to a cardiopulmonary bypass pump. The aortic balloon cannula includes an elongated tube device with first and second inflatable balloons mounted on the tube device and first and second lumen sized to communicate blood from the cardiopulmonary bypass pump to the patient's aorta. The cardiopulmonary bypass pump is configured to selectively deliver blood to the patient through the aortic balloon cannula and/or the fluid flow cannula at first, second and third temperatures.Type: GrantFiled: December 26, 2000Date of Patent: November 5, 2002Inventors: Peter Safar, S. William Stezoski, Miroslav Klain
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Patent number: 6165162Abstract: What is disclosed is a portable and modular cardiopulmonary bypass apparatus and method. The apparatus includes (i) a first cannula assembly for withdrawing blood from a patient, (ii) a pump connected to the first cannula assembly for receiving the withdrawn blood and for moving the blood through the apparatus, and (iii) a first tubing connected to the pump to transport the patient's blood away from the pump. The apparatus also includes (iv) an oxygenator for receiving blood from the first tubing and for oxygenating the blood and (v) a second cannula assembly connected to the oxygenator for returning the oxygenated blood to the patient. The apparatus may be portable so that it can be used by medical personnel anywhere. In addition, the apparatus is adapted to included one or more modules for conditioning the blood, such as modules that include a heat exchanger, blood purifier, plasma and blood cell apheresis device and others. An aortic balloon catheter is also provided.Type: GrantFiled: September 14, 1998Date of Patent: December 26, 2000Assignee: University of Pittsburgh of the Commonwealth System of Higher EducationInventors: Peter Safar, S. William Stezoski, Miroslav Klain
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Patent number: 5906588Abstract: The selective and differential perfusion method includes withdrawing blood through a cannula introduced into a patient's blood vessel. The temperature of such blood is controlled and flowed through an arterial cannula introduced into a selected arterial vessel of the patient for a sufficient time and at a sufficient flow rate to change the temperature of at least a portion of the patient's body. An aortic balloon catheter is introduced into the aorta of the patient to establish fluid communication through the catheter lumen between an external location and an aortic location which is disposed in a preferential flow relationship with a selected branch artery of the aorta leading to a selected region of the patient's body. A balloon mounted on the exterior of said aortic catheter is positioned at a balloon location spaced longitudinally from the aortic location and inflated to resist blood flow while a fluid is communicated through the catheter lumen between the external location and the aortic location.Type: GrantFiled: August 11, 1997Date of Patent: May 25, 1999Assignee: Cardeon CorporationInventors: Peter Safar, S. William Stezoski, Miroslav Klain
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Patent number: 5879316Abstract: The portable and modular cardiopulmonary bypass apparatus has met the above mentioned needs. The apparatus consists of (i) a first cannula assembly means for withdrawing blood from a patient, (ii) a pump means connected to the first cannula assembly means for receiving the withdrawn blood and for moving the blood through the apparatus, and (iii) a first tubing means connected to the pump means to transport the patient's blood away from the pump means. The apparatus further comprises (iv) oxygenator means for receiving blood from the first tubing means and for oxygenating the blood and (v) second cannula assembly means connected to the oxygenator means for returning the oxygenated blood to the patient. The apparatus is portable so that it can be used by medical personnel anywhere. In addition, the apparatus is adapted to include one or more modules for conditioning the blood, such as modules that include a heat exchanger, blood purifier, plasma and blood cell apheresis device and others.Type: GrantFiled: April 10, 1997Date of Patent: March 9, 1999Assignee: University of Pittsburgh of the Commonwealth System of Higher EducationInventors: Peter Safar, S. William Stezoski, Miroslav Klain
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Patent number: 5820593Abstract: An aortic balloon catheter including an elongated tube device formed with a first lumen sized to communicate blood between an aortic lumen of an adult human patient and a location external to the aortic lumen. Mounted on the tube device is an inflatable balloon which is sized to resist or block blood flow through the aortic lumen. The associated method of using the aortic balloon catheter includes introducing the catheter into the aortic lumen of an adult human, positioning the first lumen and the balloon, inflating the balloon and withdrawing and perfusing fluids through the first lumen.Type: GrantFiled: April 25, 1996Date of Patent: October 13, 1998Assignee: University of Pittsburg of the Commonwealth System of Higher EducationInventors: Peter Safar, S. William Stezoski, Miroslav Klain
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Patent number: 5383854Abstract: The portable and modular cardiopulmonary bypass apparatus has met the above mentioned needs. The apparatus consists of (i) a first cannula assembly means for withdrawing blood from a patient, (ii) a pump means connected to the first cannula assembly means for receiving the withdrawn blood and for moving the blood through the apparatus, and (iii) a first tubing means connected to the pump means to transport the patient's blood away from the pump means. The apparatus further comprises (iv) oxygenator means for receiving blood from the first tubing means and for oxygenating the blood and (v) second cannula assembly means connected to the oxygenator means for returning the oxygenated blood to the patient. The apparatus is portable so that it can be used by medical personnel anywhere. In addition, the apparatus is adapted to include one or more modules for conditioning the blood, such as modules that include a heat exchanger, blood purifier, plasma and blood cell apheresis device and others.Type: GrantFiled: August 19, 1992Date of Patent: January 24, 1995Assignee: University of Pittsburgh of the Commonwealth System of Higher EducationInventors: Peter Safar, S. William Stezoski, Miroslav Klain
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Patent number: 5308320Abstract: The portable and modular cardiopulmonary bypass apparatus has met the above mentioned needs. The apparatus consists of (i) a first cannula assembly means for withdrawing blood from a patient, (ii) a pump means connected to the first cannula assembly means for receiving the withdrawn blood and for moving the blood through the apparatus, and (iii) a first tubing means connected to the pump means to transport the patient's blood away from the pump means. The apparatus further comprises (iv) oxygenator means for receiving blood from the first tubing means and for oxygenating the blood and (v) second cannula assembly means connected to the oxygenator means for returning the oxygenated blood to the patient. The apparatus is portable so that it can be used by medical personnel anywhere. In addition, the apparatus is adapted to include one or more modules for conditioning the blood, such as modules that include a heat exchanger, blood purifier, plasma and blood cell apheresis device and others.Type: GrantFiled: December 28, 1990Date of Patent: May 3, 1994Assignee: University of Pittsburgh of the Commonwealth System of Higher EducationInventors: Peter Safar, S. William Stezoski, Miroslav Klain