Patents by Inventor Sa Liu

Sa Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240128441
    Abstract: Described herein are carbon-silicon composite structures and methods of producing such structures. A carbon-silicon composite structure comprises one or more carbon-containing structures that have pores at least partially filled with silicon-containing structures. Specifically, the silicon-containing structures are attached to the pore walls while maintaining void spaces within these pores. These void spaces can accommodate silicon expansion during lithiation. Carbon-silicon composite structures can be produced by submerging carbon-containing structures into a precursor liquid solution (comprising a precursor) and driving this solution into the pores. The silicon-containing structures are then formed (from the precursor) within the pores either electrochemically (e.g., by applying a voltage to the solution and structures) or chemically (e.g., by introducing the structures into a reducing liquid solution). In some examples, these void spaces are sealed from the environment by additional structures, e.g.
    Type: Application
    Filed: October 17, 2023
    Publication date: April 18, 2024
    Applicant: Gru Energy Lab Inc.
    Inventors: Xiaohua Liu, Xiahui Yao, Sa Zhou, Song Han
  • Publication number: 20210147583
    Abstract: Disclosed are a hyaluronic acid-based zwitterionic polymer brush, a preparation method thereof, and the use thereof. The structure of the zwitterionic polymer brush is represented by formula (I), wherein n is an integer from 60-150, x is an integer from 589-686, and y is an integer from 125-230. The above-mentioned zwitterionic polymer brush can delay the pathological progress of osteoarthritis, promote cartilage regeneration, and even treat osteoarthritis and improve conditions such as the generation of abraded fragments of implants such as joints and related diseases triggered thereby, and can be combined with cartilage repairing materials to improve the frictional mechanical properties thereof for achieving better repair results. Moreover, the above-mentioned zwitterionic polymer brush can selectively bind to proteins in cartilage and has an excellent lubricating effect. The present invention has the advantages of simple method, convenient operation, easy purification, high yield, and the like.
    Type: Application
    Filed: December 12, 2018
    Publication date: May 20, 2021
    Inventors: Li Ren, Sa Liu, Renjian Xie
  • Patent number: 10889898
    Abstract: The present invention discloses a method for improving the blood compatibility of a material surface by using a controllable grafting technique. The method involves placing a monomer NVP, an RAFT reagent and a solvent acetonitrile in a container, adding an initiator AIBN, mixing the same uniformly, removing oxygen with liquid nitrogen, making the same react in an oil bath; after polymerization, adding liquid nitrogen to quench and stop the reaction, thus obtaining PVP-COOH; mixing the PVP-COOH with DCC and NHS; adding dry dichloromethane to the mixture in a nitrogen atmosphere, adding mercaptoethylamine, and making the same react in darkness at room temperature; obtaining a crude sample; dissolving the crude sample in water, and performing dialysis with deoxygenated water in darkness, and then obtaining HS-PVP by freeze-drying. An Au—S bond chemisorption method is used to controllably graft an anti-protein high-molecular polymer onto an Au surface.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: January 12, 2021
    Inventors: Li Ren, Yingjun Wang, Jian Zheng, Lin Wang, Sa Liu
  • Patent number: 10758889
    Abstract: A medical macromolecular microsphere adsorbent for a blood perfusion apparatus and a preparation method thereof are provided. The polystyrene-divinylbenzene microspheres are graded by different pore sizes and specific surface areas, medically purified, and grafted by a bioactivity-controlled grafting technology. In the microsphere adsorbent, the volume ratio of microspheres with pore sizes of 1-10 ?m, 10-100 ?m and 100 ?m is 1:(1-10):(1-20), the content of residual monomers in the microsphere has O.D190-400 nm?0.03. The microsphere adsorbent not only can adsorb harmful micromolecules in blood but also can effectively adsorb harmful medium-molecules and macromolecules in blood, thereby meeting clinical application demands.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: September 1, 2020
    Inventors: Li Ren, Yingjun Wang, Sa Liu, Lin Wang, Jian Zheng
  • Publication number: 20200255951
    Abstract: The present invention discloses a method for improving the blood compatibility of a material surface by using a controllable grafting technique. The method involves placing a monomer NVP, an RAFT reagent and a solvent acetonitrile in a container, adding an initiator AIBN, mixing the same uniformly, removing oxygen with liquid nitrogen, making the same react in an oil bath; after polymerization, adding liquid nitrogen to quench and stop the reaction, thus obtaining PVP-COOH; mixing the PVP-COOH with DCC and NHS; adding dry dichloromethane to the mixture in a nitrogen atmosphere, adding mercaptoethylamine, and making the same react in darkness at room temperature; obtaining a crude sample; dissolving the crude sample in water, and performing dialysis with deoxygenated water in darkness, and then obtaining HS-PVP by freeze-drying. An Au—S bond chemisorption method is used to controllably graft an anti-protein high-molecular polymer onto an Au surface.
    Type: Application
    Filed: December 8, 2016
    Publication date: August 13, 2020
    Inventors: Li Ren, Yingjun Wang, Jian Zheng, Lin Wang, Sa Liu
  • Publication number: 20180280930
    Abstract: A medical macromolecular microsphere adsorbent for a blood perfusion apparatus and a preparation method thereof are provided. The polystyrene-divinylbenzene microspheres are graded by different pore sizes and specific surface areas, medically purified, and grafted by a bioactivity-controlled grafting technology. In the microsphere adsorbent, the volume ratio of microspheres with pore sizes of 1-10 ?m, 10-100 ?m and 100 ?m is 1:(1-10):(1-20), the content of residual monomers in the microsphere has O.D190-400 nm?0.03. The microsphere adsorbent not only can adsorb harmful micromolecules in blood but also can effectively adsorb harmful medium-molecules and macromolecules in blood, thereby meeting clinical application demands.
    Type: Application
    Filed: June 7, 2018
    Publication date: October 4, 2018
    Inventors: LI REN, YINGJUN WANG, SA LIU, LIN WANG, JIAN ZHENG
  • Patent number: 6341833
    Abstract: First, image data are converted to first tone data for primary color inks, and then converted to second tone data for primary color and black inks, by under color elimination. The combinations of the above tone data for primary color and black inks, in which bronzing occurs when images are printed on the printing medium, are recorded beforehand as the conditions under which bronzing occurs. The determination of whether or not the conditions under which bronzing occurs are present in the above second tone data is made according to these conditions under which bronzing occurs. If bronzing will occur, a part of the under color elimination is converted to primary color inks. In this way, it becomes possible to print images in which bronzing does not occur. This process may also be executed by using color conversion tables.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: January 29, 2002
    Assignee: Seiko Epson Corporation
    Inventors: Sa Liu, Yuko Yamamoto
  • Patent number: 6310637
    Abstract: In a printer that allows dual-way printing, a test pattern is formed to adjust the print timing with a high accuracy, or more concretely to eliminate a deviation of dots created in the course of a main scan in a backward direction from dots created in the course of the main scan in a forward direction. The test pattern is based on a normal dither matrix. The test pattern includes a plurality of dots that are regularly arranged both in a main scanning direction and in a sub-scanning direction. When the test pattern is printed at an appropriate timing, it is observed as a substantially homogeneous state without unevenness of the density. In case that the dot print timing is deviated, on the other hand, a deviation in dot interval causes unevenness of the density. The deviation of the dot print timing is accurately detected, based on the presence or the non-presence of such unevenness of the density.
    Type: Grant
    Filed: July 22, 1998
    Date of Patent: October 30, 2001
    Assignee: Seiko Epson Corporation
    Inventors: Kazumichi Shimada, Sa Liu
  • Patent number: 6293643
    Abstract: The printing apparatus of the present invention adopts the technique of effectively utilizing two or more different types of dots having different ink densities and different ink weights. The printing apparatus has a head that provides inks of different densities with respect to at least one color and creates dots of different diameters. The density per unit area is varied by changing the combination of the ink density and the dot diameter. In the half tone area, the lightness of smaller dark dots is made substantially coincident with the lightness of larger light dots. Both the smaller dark dots and the larger light dots are created in the half tone, so as to prevent the banding from occurring in a resulting printed image. The smaller dark dots and the larger light dots may be arranged according to a predetermined pattern or at random. The pattern should be set by taking into account the ink duty of the recording paper.
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: September 25, 2001
    Assignee: Seiko Epson Corporation
    Inventors: Kazumichi Shimada, Shixin Zhou, Yukimitsu Fujimori, Sa Liu