Patents by Inventor Sabera Ruzdijic

Sabera Ruzdijic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Control of CD44 gene expression for therapeutic use
    Patent number: 5990299
    Abstract: Neoplastic cells which over-express CD44, including especially non-small cell lung cancer and melanoma cancer cells, are treated with antisense oligonucleotides to control CD44 expression. Test results show that the claimed oligonucleotides significantly decreases cell growth in a CD44 sequence specific manner of lung cancer or melanoma cells, or both, but are largely non-toxic to normal cells. Examples of dosing in a clinical setting are provided.
    Type: Grant
    Filed: August 14, 1995
    Date of Patent: November 23, 1999
    Assignee: ICN Pharmaceuticals, Inc.
    Inventors: Sabera Ruzdijic, Zbigniew Pietrzkowski, Dariusz Cieslak