Abstract: A method and apparatus for dissolving urea. In one embodiment, the method comprises the steps of providing a mixing container, depositing a predetermined amount of urea into the mixing container, and depositing a predetermined amount of water into the mixing chamber to achieve a predetermined urea/water concentration. In a preferred embodiment, the predetermined urea/water concentration is about 50/50 wt/wt. The method further comprises the steps of mixing the urea and water to form a mixture, allowing the mixture to stand until the temperature of the mixture reaches a predetermined temperature, and thereafter, resuming mixing of the mixture until the urea completely dissolves in the water.

Abstract: A disposable cold pack comprising a durable flexible container having an interior region, a breakable envelope contained within the interior region, a predetermined amount of liquid contained within the envelope wherein the liquid consists of water, and solid materials contained within the interior region. The solid materials consist of a predetermined amount of urea and a predetermined amount of potassium chloride. When the envelope is broken so as to release water into the interior region, the water dissolves a substantial amount of the solid materials thereby producing an endothermic reaction which cools the water.

Abstract: A process for preparing a compounds of the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof, which comprises reacting a piperazine salt of the formula ##STR2## with an alkyl halide containing compound of the formula ##STR3## in water with a reagent to neutralize the hydrohalic acid and heating the mixture under conditions which are suitable to effect the coupling of said piperazine salt with said alkyl halide containing compound.

Abstract: The monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydr o-2H-indole-2-one hydrochloride has advantageous stability for formulation as a neuroleptic agent.

Abstract: A removable wheel and handle apparatus for use with trash receptacles such as garbage cans or the like includes a handle adapted to engage the open edge of the trash receptacle, a bracket affixed to the bottom of the receptacle and a wheel assembly adapted to removably receive an extending portion of the bracket. The handle permits easy tilting of the trash receptacle on to the wheel assembly, thereby permitting the receptacle to be readily moved from one place to another. The handle and the wheel assembly may then be removed and applied to another receptacle in a like manner.