Patents by Inventor Sabina Mariotti

Sabina Mariotti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Retro-inverso analogues of thymopentin and the method for their synthesis
    Patent number: 5218089
    Abstract: New analogues of thymopentin (TP5) and of its tetrapeptide fragment (TP5.sup.1-4) containing two non-contiguous retro-inverted bonds in the peptide chain are described which are of the general formula (I) ##STR1## where R is hydrogen or an acyl radical, and R.sup.1 is an --OR.sup.2 group or an ##STR2## group where R.sup.2 is a hydrogen atom or a hydrocarbon radical, and R.sup.3 is a hydrogen atom or a hydroxyl group, and the corresponding pharmaceutically acceptable salts of acid or basic addition, possess immunomodulating activity.
    Type: Grant
    Filed: November 26, 1991
    Date of Patent: June 8, 1993
    Assignee: Sclavo S.p.A.
    Inventors: Sabina Mariotti, Alessandro Sisto, Luciano Nencioni, Luigi Villa, Antonio S. Verdini
  • Retro-inverso analogues of thymopentin, and their use in the preparation of pharmaceutical compositions
    Patent number: 5091510
    Abstract: New analogues of thymopentin (TP5) and of its tetrapeptide fragment (TP5.sup.1-4) containing two non-contiguous retro-inverted bonds in the peptide chain are described.The new compounds, of general formula (I) ##STR1## where R is hydrogen or an acyl radical, andR.sup.1 is an --OR.sup.2 group or an ##STR2## group where R.sup.2 is a hydrogen atom or a hydrocarbon radical, and R.sup.3 is a hydrogen atom or a hydroxyl group,and the corresponding pharmaceutically acceptable salts of acid or basic addition, possess immunomodulating activity.
    Type: Grant
    Filed: December 21, 1989
    Date of Patent: February 25, 1992
    Assignee: Scalvo, S.p.A.
    Inventors: Sabina Mariotti, Alessandro Sisto, Luciano Nencioni, Luigi Villa, Antonio S. Verdini