Patents by Inventor Sabina Wunschmann

Sabina Wunschmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Full-length GB virus C (hepatitis G virus) RNA transcripts are infectious in primary CD4 positive T cells
    Patent number: 6870043
    Abstract: GB virus C (GBV-C or hepatitis G virus) is a recently described flavivirus that frequently leads to chronic viremia in humans. Although associated with acute post-transfusion hepatitis, it is not clear if GBV-C is pathogenic for humans. A full-length cDNA was constructed from the plasma of a person with chronic GBV-C viremia. Peripheral blood mononuclear cells (PBMCs) transfected with full-length RNA transcripts from this GBV-C clone resulted in viral replication, demonstrating an isolated infectious GBV-C nucleic acid molecule. In addition to composition involving an isolated infectious GBV-C nucleic acid molecule, the present invention concerns methods of inhibiting and treating HIV infections.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: March 22, 2005
    Assignee: The University of Iowa Research Foundation
    Inventors: Jinhua Xiang, Sabina Wünschmann, Warren Schmidt, Jack Stapleton
  • Full-length GB virus C (hepatitis G virus) RNA transcripts are infectious in primary CD4 positive T cells and methods of treating HIV
    Publication number: 20030170870
    Abstract: GB virus C (GBV-C or hepatitis G virus) is a recently described flavivirus that frequently leads to chronic viremia in humans. Although associated with acute post-transfusion hepatitis, it is not clear if GBV-C is pathogenic for humans. A full-length cDNA was constructed from the plasma of a person with chronic GBV-C viremia. Peripheral blood mononuclear cells (PBMCs) transfected with full-length RNA transcripts from this GBV-C clone resulted in viral replication, demonstrating an isolated infectious GBV-C nucleic acid molecule. In addition to composition involving an isolated infectious GBV-C nucleic acid molecule, the present invention concerns methods of inhibiting and treating HIV infections.
    Type: Application
    Filed: April 5, 2001
    Publication date: September 11, 2003
    Inventors: Jinhua Xiang, Sabina Wunschmann, Warren Schmidt, Jack Stapleton