Patents by Inventor Sachin Chaugule

Sachin Chaugule has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE THERAPEUTICS FOR FIBRODYSPLASIA OSSIFICANS PROGRESSIVA
    Publication number: 20230295662
    Abstract: In some aspects, the disclosure relates to compositions and methods for treating fibrodysplasia ossificans progressiva (FOP) in a subject. In some aspects, the disclosure provides isolated nucleic acids, and vectors such as rAAV vectors, configured to express transgenes that inhibit (e.g., decrease) expression of mutated AVCR1 gene in muscle cells or connective tissues.
    Type: Application
    Filed: April 21, 2023
    Publication date: September 21, 2023
    Applicant: University of Massachusetts
    Inventors: Jae-Hyuck Shim, Guangping Gao, Jun Xie, Yeon-Suk Yang, Jung min Kim, Sachin Chaugule
  • Gene therapeutics for fibrodysplasia ossificans progressiva
    Patent number: 11674154
    Abstract: In some aspects, the disclosure relates to compositions and methods for treating fibrodysplasia ossificans progressiva (FOP) in a subject. In some aspects, the disclosure provides isolated nucleic acids, and vectors such as rAAV vectors, configured to express transgenes that inhibit (e.g., decrease) expression of mutated AVCR1 gene in muscle cells or connective tissues.
    Type: Grant
    Filed: December 2, 2021
    Date of Patent: June 13, 2023
    Assignee: University of Massachusetts
    Inventors: Jae-Hyuck Shim, Guangping Gao, Jun Xie, Yeon-Suk Yang, Jung min Kim, Sachin Chaugule
  • DEVELOPMENT OF NOVEL GENE THERAPEUTICS FOR FIBRODYSPLASIA OSSIFICANS PROGRESSIVA
    Publication number: 20220177915
    Abstract: In some aspects, the disclosure relates to compositions and methods for treating fibrodysplasia ossificans progressiva (FOP) in a subject. In some aspects, the disclosure provides isolated nucleic acids, and vectors such as rAAV vectors, configured to express transgenes that inhibit (e.g., decrease) expression of mutated AVCR1 gene in muscle cells or connective tissues.
    Type: Application
    Filed: December 2, 2021
    Publication date: June 9, 2022
    Applicant: University of Massachusetts
    Inventors: Jae-Hyuck Shim, Guangping Gao, Jun Xie, Yeon-Suk Yang, Jung Min Kim, Sachin Chaugule