Patents by Inventor Sachin Shivaji Patil

Sachin Shivaji Patil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of dabigatran
    Patent number: 9688657
    Abstract: The present invention relates to a process for preparation of Dabigatran etexilate or pharmaceutically acceptable salt thereof. The present invention relates to novel compounds, in particular Ethyl-3-{[(2-formyl-1-methyl-1H-benzimidazole-5-yl)carbonyl]-(2-pyridinyl) amino}propanoate and Ethyl-3-{[(2-dichloromethyl-1-methyl-1H-benzimidazole-5-yl)carbonyl]-(2-pyridinyl)amino}propanoate and process for preparation thereof. The present invention further relates to the use of these novel compounds in the preparation of Dabigatran etexilate or pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: June 27, 2017
    Assignee: USV Private Limited
    Inventors: Laxmikant Narhari Patkar, Harish Kashinath Mondkar, Nitin Dnyaneshwar Arote, Sachin Shivaji Patil, Tanaji Shamrao Jadhav, Nitin Nivrutti Hagavane, Rajesh Ganpat Bhopalkar
  • SYNTHESIS OF DABIGATRAN
    Publication number: 20160060248
    Abstract: The present invention relates to a process for preparation of Dabigatran etexilate or pharmaceutically acceptable salt thereof. The present invention relates to novel compounds, in particular Ethyl-3-{[(2-formyl-1-methyl-1H-benzimidazole-5-yl)carobonyl]-(2-pyridinyl)amino}propanoate and Ethyl-3-{[(2-dichloromethyl-1-methyl-1H-benzimidazole-5-yl)carbonyl]-(2-pyridinyl)amino} propanoate and process for preparation thereof. The present invention further relates to the use of these novel compounds in the preparation of Dabigatran etexilate or pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 25, 2014
    Publication date: March 3, 2016
    Inventors: Laxmikant Narhari Patkar, Harish Kashinath Mondkar, Nitin Dnyaneshwar Arote, Sachin Shivaji Patil, Tanaji Shamrao Jadhav, Nitin Nivurtti Hagavane, Rajesh Ganpat Bhopalkar
  • Process For the Preparation of Highly Pure (E) N,N-Diethyl-2-Cyano-3-(3,4-Dihydroxy-5-Nitro Phenyl) Acrylamide (Entacapone)
    Publication number: 20080319226
    Abstract: A process for the preparation of highly pure (E)-N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide (Entacapone). It comprises condensing 3,4-dihydroxy-5-nitro benzaldehyde with N,N-diethyl cyano acetamide in an organic solvent in the presence of an organic base and an acid under reflux conditions followed by distilling off the solvent under vacuum and treating the residue with a lower aliphatic carboxylic acid at 40-8O0 C. The resulting residue is extracted with a chlorinated solvent and the solvent is distilled off under vacuum. The resulting residue is extracted with an organic solvent to obtain crude N,N-diethyl-2-cyano-3-3,4-dihydroxy-5-nitrophenyl)acrylamide. The crude product N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl) acrylamide formed is treated with a mixture of organic alcohol and organic acid in the molar ratio of the crude product to organic alcohol 1:5 to 15 and crude product to organic acid 1:1 to 3 under reflux conditions.
    Type: Application
    Filed: November 9, 2005
    Publication date: December 25, 2008
    Applicant: USV LIMITED
    Inventors: Venkatasubramanian Radhakrishnan Tarur, Dhananjay Govind Sathe, Nandu Baban Bhise, Avinash Venkatraman Naidu, Umesh Parashram Aher, Sachin Shivaji Patil